Attachment 2 - 60 Day Federal Register Notice

21021

Federal Register / Vol. 72, No. 81 / Friday April 27, 2007 / Notices
Affected Public: Not-for-profit
institutions.
Annual Number of Respondents: 833.
Total Annual Responses: 833.
Average Burden per Response: 34
minutes.
Total Annual Hours: 472.
To obtain copies of the supporting
statement and any related forms for the
proposed paperwork collections
referenced above, e-mail your request,
including your address, phone number,
OMB number, and OS document
identifier, to
[email protected], or call
the Reports Clearance Office on (202)
690–6162. Written comments and
recommendations for the proposed
information collections must be
received within 30 days of this notice
directly to the Desk Officer at the
address below: OMB Desk Officer: John
Kraemer, OMB Human Resources and
Housing Branch, Attention: (OMB
#0990–New), New Executive Office
Building, Room 10235, Washington, DC
20503.
Dated: April 17, 2007.
Alice Bettencourt,
Office of the Secretary, Paperwork Reduction
Act Reports Clearance Officer.
[FR Doc. E7–8050 Filed 4–26–07; 8:45 am]
BILLING CODE 4150–33–P

DEPARTMENT OF HEALTH AND
HUMAN SERVICES

request more information on the
proposed projects or to obtain a copy of
the data collection plans and
instruments, call 404–639–5960 and
send comments to Joan Karr, CDC
Acting Reports Clearance Officer, 1600
Clifton Road, MS–D74, Atlanta, GA
30333 or send an e-mail to
[email protected].
Comments are invited on: (a) Whether
the proposed collection of information
is necessary for the proper performance
of the functions of the agency, including
whether the information shall have
practical utility; (b) the accuracy of the
agency’s estimate of the burden of the
proposed collection of information; (c)
ways to enhance the quality, utility, and
clarity of the information to be
collected; and (d) ways to minimize the
burden of the collection of information
on respondents, including through the
use of automated collection techniques
or other forms of information
technology. Written comments should
be received within 60 days of this
notice.
Proposed Project
Experimental and Theoretical Study
of Early Detection and Isolation of
Influenza—NEW—The National
Institute for Occupational Safety and
Health (NIOSH), Centers for Disease
Control and Prevention (CDC).
Background and Brief Description

Centers for Disease Control and
Prevention
[60Day–07–07AW]

Proposed Data Collections Submitted
for Public Comment and
Recommendations
In compliance with the requirement
of Section 3506(c)(2)(A) of the
Paperwork Reduction Act of 1995 for
opportunity for public comment on
proposed data collection projects, the
Centers for Disease Control and
Prevention (CDC) will publish periodic
summaries of proposed projects. To

The Federal Occupational Safety and
Health Act of 1970, section 501, enables
NIOSH to carry out research relevant to
the health and safety of workers. Some
diseases like influenza and Severe
Acute Respiratory Syndrome (SARS)
can be spread when people produce
clouds of droplets (called aerosols) by
coughing or sneezing. Aerosol
transmission of infectious diseases is of
particular interest today because of
increased concern over a possible global
influenza pandemic. The possible
airborne spread of influenza is
especially important to health-care
workers and emergency responders,
who face a much greater risk of

exposure than does the general public.
However, substantial gaps exist in our
understanding of the generation and
spread of infectious aerosols containing
influenza. This lack of information
hampers the ability of health scientists
to model and predict the transmission of
influenza by airborne particles and to
understand whether or not aerosols are
likely to be an important route of
transmission of influenza during a
pandemic.
The purpose of this study is to gain
a better understanding of the production
and dissemination of aerosols
containing the influenza virus. The
results of this research will give
scientists and health professional’s
greater insight into the airborne
transmission of influenza and allow
them to better assess the potential
effectiveness of preventive measures.
The first part of this study will
measure the quantity and size
distribution of aerosol droplets
produced by people with influenza
when they cough. To accomplish this,
volunteers with influenza-like illness
will be asked to provide an oral swab for
influenza testing, and then will cough
into a spirometer. The aerosol produced
by each person will be measured using
commercially-available instrumentation.
The oral swabs will be processed after
the aerosol experiments are completed.
The second part of this study will
determine the amount and size of
airborne particles containing influenza
virus that are present in a hospital
emergency department during influenza
season. Health care workers will be
recruited to wear small aerosol
collection devices as they go about their
normal duties. The collected samples
will then be analyzed for influenza
virus. Adult patients in the emergency
department with influenza-like illness
will be asked to provide an oral swab to
test for the flu virus in order to estimate
the number of potential sources of viralladen airborne particles. There will be
no costs to study participants other than
their time.

ESTIMATED ANNUALIZED BURDEN HOURS
Number of
respondents

cprice-sewell on PROD1PC66 with NOTICES

Respondents

Average
burden per
response
(in hours)

Number of
responses per
respondent

Part 1 participants ..........................................................................................
Part 2 health care workers ............................................................................
Part 2 patients ...............................................................................................

40
30
15

2
1
1

1
1
0.5

Total ........................................................................................................

........................

........................

........................

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27APN1

Total burden
(in hours)
80
30
8.0
118

21022

Federal Register / Vol. 72, No. 81 / Friday April 27, 2007 / Notices

Dated: April 23, 2007.
Joan F. Karr,
Acting Reports Clearance Officer, Centers for
Disease Control and Prevention.
[FR Doc. E7–8073 Filed 4–26–07; 8:45 am]

National Institute for Occupational
Safety and Health (NIOSH), Centers for
Disease Control and Prevention (CDC).

BILLING CODE 4163–18–P

Beryllium is a lightweight metal with
many applications. Exposed workers
may be found in the primary
production, nuclear power and
weapons, aerospace, scrap metal
reclamation, specialty ceramics, and
electronics industries, among others.
The size of the USA workforce at risk
of chronic beryllium disease (CBD),
from either current or past work-related
exposure to the metal, may be as high
as one million. Demand for beryllium is
growing worldwide, which means that
increasing numbers of workers are likely
to be exposed.
Exposure to beryllium can lead to
sensitization and cause an immunologic
granulomatous lung disease.
Sensitization is a cell-mediated allergictype response that may be detected in
the peripheral blood with the beryllium
lymphocyte proliferation test (BeLPT),
which is used by the industry as a
surveillance tool. Workers found to be
sensitized may be clinically evaluated
for CBD with tests including
bronchoalveolar lavage and
transbronchial biopsy. Cross-sectional
studies in various beryllium workplace
populations have identified
sensitization in the range of less than
1% to 14% of workers. The proportion
of sensitized workers who have
beryllium disease at initial clinical
evaluation has varied from 10 to 100%
in different workplaces. Sensitized
workers not initially diagnosed with
CBD are often diagnosed with the
disease upon follow-up, but whether all
sensitized workers will eventually
develop beryllium disease is unknown.
Industry screening programs have
enabled the identification of CBD in
persons without apparent symptoms,
often early in disease progression (often
referred to as ‘‘subclinical disease’’).
Progression from sensitization to
subclinical disease to clinical
impairment, while difficult to predict
for any one individual, is not
uncommon.

DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Centers for Disease Control and
Prevention
[60Day–07–07AY]

Proposed Data Collections Submitted
for Public Comment and
Recommendations
In compliance with the requirement
of section 3506(c)(2)(A) of the
Paperwork Reduction Act of 1995 for
opportunity for public comment on
proposed data collection projects, the
Centers for Disease Control and
Prevention (CDC) will publish periodic
summaries of proposed projects. To
request more information on the
proposed projects or to obtain a copy of
the data collection plans and
instruments, call 404–639–5960 and
send comments to Joan Karr, CDC
Acting Reports Clearance Officer, 1600
Clifton Road, MS–D74, Atlanta, GA
30333 or send an e-mail to
[email protected].
Comments are invited on: (a) Whether
the proposed collection of information
is necessary for the proper performance
of the functions of the agency, including
whether the information shall have
practical utility; (b) the accuracy of the
agency’s estimate of the burden of the
proposed collection of information; (c)
ways to enhance the quality, utility, and
clarity of the information to be
collected; and (d) ways to minimize the
burden of the collection of information
on respondents, including through the
use of automated collection techniques
or other forms of information
technology. Written comments should
be received within 60 days of this
notice.
Proposed Project
Long-Term Efficacy of a Program to
Prevent Beryllium Disease—New—

Currently, there are no preventive
programs that have been demonstrated
to have long-term effectiveness in
preventing beryllium sensitization and
CBD among beryllium-exposed workers.
In the United States, recent short-term
evidence (i.e., average work tenure 16
months, maximum four years) at one
facility suggests that the comprehensive
preventive program that was
implemented by company management
beginning in 2000 has successfully
reduced the incidence of beryllium
sensitization, as defined by the
occurrence of confirmed abnormal
BeLPTs. However, the follow-up has
thus far been limited to current workers,
the duration has been too short to
document a reduced incidence of CBD,
and it is possible that sensitization has
been delayed, rather than prevented.
Evaluation of this program’s
effectiveness would therefore be more
complete by including individuals who
have left employment and documenting
whether: (1) The program was effective
at two other facilities at which it was
implemented, (2) the program prevented
beryllium sensitization over a longer
period of time (i.e., up to eight years);
and (3) the program prevented CBD,
which generally takes longer to develop.

Background and Brief Description

Study Design
This proposed study is designed to
evaluate the effectiveness of a
comprehensive preventive program at
three beryllium plants. Eligible workers
for this survey include those hired
between implementation of a
comprehensive program (2000–01) and
December 31, 2008, including any
already known to be sensitized. NIOSH
will offer all eligible current and former
workers the BeLPT to identify
sensitization and administer a work and
medical history questionnaire.
There are no costs to former worker
respondents except their time to
participate in the interview. Current
workers will participate during work
hours, and will thus be compensated for
their time by their employer. Former
workers will participate during their
own time.

ESTIMATE OF ANNUALIZED BURDEN HOURS
Number of
respondents

cprice-sewell on PROD1PC66 with NOTICES

Respondents
Current Workers ..............................................................................................
Former Workers ...............................................................................................

239
340

Total ..........................................................................................................

579

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Number of
responses/respondent

E:\FR\FM\27APN1.SGM

1
1

Avg. burden/
response
(in hours)
45/60
45/60

Total burden
(in hours)
179
255
434

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