The request does
not constitute a "nonsubstantive change" and will need to be
resubmitted as a regular change request.
Inventory as of this Action
Requested
Previously Approved
10/31/2011
10/31/2011
10/31/2011
6,861
0
6,861
4,140
0
4,140
0
0
0
The Agricultural Health Study (AHS) is
a cohort study of 89,568 licensed pesticide applicators and their
spouses in Iowa and North Carolina to be followed for 20 years or
more. The focus of the phase III follow-up period (2005-2008) is to
update exposure information and health histories by means of a
computer assisted telephone interview, and to follow the cohort to
determine disease incidence and mortality. This request is to
complete the follow-up for phase III for 20,583 enrolled subjects
who were not contacted previously due to a slow release of funding
to the field centers resulting in an unexpected slow rate of data
collection. The stimulus for this prospective investigation comes
from the growing evidence that, despite a low mortality overall,
farmers experience an excess of several cancers. A small sub-set of
the cohort (N=993) will be asked to participate in the buccal cell
collection to assess the effect of inherited polymorphisms and the
interaction of environment and genomic predisposition.
US Code:
42
USC 285a-2 Name of Law: Public Health Service Act
The phase III collection was
scheduled for 3 years (November 2005 through October 2008). As it
was stated in the prior submission, it was anticipated that "it may
be necessary to extend data collection to a fourth year." The Field
Stations have always been aware that conducting CATI interviews of
farmers during the planting and harvesting season was potentially
burdensome to the study participants, so data collection is
suspended during those time periods, which vary from year to year
depending on the weather. Budgetary issues created circumstances
that made fewer resources available in a timely manner than
anticipated for phase III, so questionnaire administration will
take additional time rather than the three years required during
phase II. Funding for the project was slowed down so it has become
necessary to extend the length of time for data collection. Though
this request represents respondents that were not interviewed,
burden hours that were not used, and costs that were not spent
during the 2005-2008 data collection period, a revision to this
request is being ask due to a reduction in burden hours from the
previous OMB approval. This request will allow the Agricultural
Health Study to complete phase III of its research.
On behalf of this Federal agency, I certify that
the collection of information encompassed by this request complies
with 5 CFR 1320.9 and the related provisions of 5 CFR
1320.8(b)(3).
The following is a summary of the topics, regarding
the proposed collection of information, that the certification
covers:
(i) Why the information is being collected;
(ii) Use of information;
(iii) Burden estimate;
(iv) Nature of response (voluntary, required for a
benefit, or mandatory);
(v) Nature and extent of confidentiality; and
(vi) Need to display currently valid OMB control
number;
If you are unable to certify compliance with any of
these provisions, identify the item by leaving the box unchecked
and explain the reason in the Supporting Statement.
Form 1 Phase III CATI v. 2 Instrument for Agricultural Health Study
AHS Biomarker Study - OMB memo 01-07-10.doc
Phase III CATI v. 2 Instrument for Agricultural Health Study