ICR#0923-0043_Justification for change-_June 2012

OMB ICR# 0923-0043

Expiration Date: 04/30/2014

Title of Approved Information Collection: Creation of State and Metropolitan Area Based Surveillance Projects for Amyotrophic Sclerosis (ALS)

Justification for change:

We are requesting a non-substantive change to OMB 0923-0043, Creation of State and Metropolitan Area Based Surveillance Projects for Amyotrophic Lateral Sclerosis (ALS), expiration date April 30, 2014, to allow the inclusion of two additional metropolitan areas, Baltimore and Las Vegas, in the project.

The original protocol specified the participation of 3 states and 4-6 metropolitan areas. OMB has approved the inclusion of Florida, New Jersey, and Texas and the metropolitan areas of Atlanta, Chicago, Detroit, Los Angeles, Philadelphia, and San Francisco. The original burden estimate was based on the inclusion of New York City as one of the 6 metropolitan areas. The original burden estimate of 703 hours per year (2109 total) was based on 2250 cases per year (6750 total). The expected cases from these 3 states and 6 metropolitan areas is 6384. Because New York City did not participate in the project, we did not achieve the expected number of cases (burden hours) anticipated. To maximize the data available to evaluate the completeness of the National ALS Registry and have a highly diverse population, we are requesting the approval to add two additional metropolitan areas, Baltimore (Baltimore City, Baltimore and Howard Counties) and Las Vegas. The addition of these two sites brings the expected number of cases for the entire project, 3 states and 8 metropolitan areas to 6677.

No change to burden or number of respondents.