4 Crosswalk of PATH Study Objectives, Data Sources, Domains, and Analysis

Population Assessment of Tobacco and Health (PATH) Study (NIDA)

Attachment 4
Crosswalk of PATH Objectives, Data Sources,
Domains, and Analysis
June 18, 2013

Population Assessment of Tobacco and Health (PATH) Study (NIDA)

Objective

1. Identify and
explain trends in
tobacco use
patterns

2. Identify and
explain trends in
risk perceptions

Data Source

Crosswalk of PATH Study Objectives, Data Sources, Domains, and Analysis
Domain / Questionnaire Component
Analysis

Adult, Youth, Parent,
Screener, Tobacco Use
Form, Biospecimen

Demographics, tobacco use, cigarette section, ecigarette section, cigar section, pipe section,
waterpipe section, snus section, smokeless section,
dissolvable section, poly use section, nicotine
dependence section, secondhand smoke exposure
section

Examine the prevalence of each product
cross sectionally and examine rates of
quitting, initiation, and relapse
longitudinally overall and by demographics
and other subgroups such as dependence
and the presence of comorbidities.

Adult, Youth, Parent

Demographics, tobacco use, cigarette section, ecigarette section, cigar section, pipe section,
waterpipe section, snus section, smokeless section,
dissolvable section, poly use section, nicotine
dependence section, packaging and health warnings
section, product regulation, modified risk product
section, media utilization section, industry
advertising and promotion section

Examine the levels of risk perceptions of
different tobacco products cross-sectionally
and to assess change prospectively overall
and by demographics and other subgroups.

3. Characterize the
natural history of Adult, Youth, Parent,
cessation and
Screener, Tobacco Use
relapse
Form, Biospecimen

Demographics, tobacco use, cigarette section, ecigarette section, cigar section, pipe section,
waterpipe section, snus section, smokeless section,
dissolvable section, poly use section, nicotine
dependence section, secondhand smoke exposure
section

4. Compare
intermediate
endpoints and
health outcomes
by tobacco user
status

Demographics, tobacco use, cigarette section, ecigarette section, cigar section, pipe section,
waterpipe section, snus section, smokeless section,
dissolvable section, poly use section, nicotine
dependence section, secondhand smoke exposure
section, health effects section

Adult, Youth, Parent,
Screener, Tobacco Use
Form, Biospecimen

1

Longitudinally examine rates of quit
attempts, brand and product switching, and
actual cessation and relapse overall and by
subgroup.
Examine rates of adverse health outcomes
cross-sectionally and compare between
different types of tobacco product users /
nonusers. Longitudinally examine the rate
of onset of adverse health outcomes by
tobacco product user status (user, recent
quitter, product switcher, poly-product
user)

Population Assessment of Tobacco and Health (PATH) Study (NIDA)

Objective

Domain / Questionnaire Component

Analysis

5. Evaluate the
Adult, Youth, Parent,
effects of FSPTCA Screener, Tobacco Use
regulations
Form, Biospecimen

(All sections used) Demographics, tobacco use,
cigarette section, e-cigarette section, cigar section,
pipe section, waterpipe section, snus section,
smokeless section, dissolvable section, poly use
section, nicotine dependence section, packaging and
health warnings section, product
regulation/modified risk product section, peer and
family influences section, health effects section,
industry advertising and promotion section

Utilize regulatory conceptual models to
identify changes in regulatory-specific
intermediate variables and behaviors (see
Attachment 3b).

6. Assess
differences in
attitudes,
behaviors, and
health outcomes
by subgroup

Adult, Youth, Parent,
Screener, Tobacco Use
Form, Biospecimen

Demographics, tobacco use, cigarette section, ecigarette section, cigar section, pipe section,
waterpipe section, snus section, smokeless section,
dissolvable section, poly use section, nicotine
dependence section, peer and family influences
section, health effects outcome section

This is essentially the analysis plan for
Objectives 1, 2, and 4 but broken down by
subgroup. Subgroups of particular interest
are demographic subgroups and persons
with comorbidities such other substance
use or physical or mental health problems.

Adult, Youth, Parent,
Screener, Tobacco Use
Form, Biospecimen

(All sections used) Demographics, tobacco use,
cigarette section, e-cigarette section, cigar section,
pipe section, waterpipe section, snus section,
smokeless section, dissolvable section, poly use
section, nicotine dependence section, packaging and
health warnings section, product
regulation/modified risk product section, media
utilization section, secondhand smoke section, peer
and family influences section, health effects section,
industry advertising and promotion section

This is essentially the analysis plan for
Objectives 1, 2, and 4 but broken down by
subgroup. The main subgroups of interest
for this objective are persons with different
tobacco use statuses (nonuser, users of each
type of product, poly tobacco product users,
quitters by length of time quit)

7. Compare nonusers and former
users trends in
use, risk
perceptions, and
health outcomes

Data Source

2