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pdfAMAP RING TEST FOR PERSISTENT ORGANIC
POLLUTANTS IN HUMAN SERUM
(AMAP)
Scope of accreditation:
REPORT FOR ROUND:
2014-01
PTMS SHIPPING DATE:
2014-01-27
DATE OF PUBLICATION:
2014-04-11
The concentrations of PCB IUPAC # 138 in material AM-S-W1403,
PCB IUPAC # 153 in material AM-S-W1402, p,p’-DDE in material
AM-S-W1401, PBDE IUPAC 153 in material AM-S-W1401, PFHxA in material
AM-S-Y1402 and PFHxS in material AM-S-Y1403 exceed the level of our
scope of accreditation.
Total cholesterol, total lipids and triglycerides are not included in our
scope of accreditation.
Centre de toxicologie/INSPQ
945, Ave Wolfe
Québec, QC
Canada, G1V 5B3
Phone: (418) 650-5115 Ext. 5254
Fax : (418) 654-2148
E-mail : [email protected]
http://www.inspq.qc.ca/ctq
AMAP Ring Test for Persistent Organic
Pollutants in Human Serum
TABLE OF CONTENTS
INTRODUCTION
1
SERUM
Dieldrin
2
ß-HCH
5
Heptachlor
8
Heptachlor epoxide
11
Hexachlorobenzene
14
Oxychlordane
17
p,p’-DDE
20
p,p’-DDT
23
PBDE IUPAC # 28
26
PBDE IUPAC # 47
29
PBDE IUPAC # 99
32
PBDE IUPAC # 100
35
PBDE IUPAC # 153
38
PBDE IUPAC # 154
41
PBDE IUPAC # 183
44
PBDE IUPAC # 209
47
PCB IUPAC # 28
50
PCB IUPAC # 74
53
PCB IUPAC # 99
56
PCB IUPAC # 105
59
PCB IUPAC # 118
62
PCB IUPAC # 138
65
PCB IUPAC # 153
68
PCB IUPAC # 170
71
PCB IUPAC # 180
74
Centre de toxicologie/INSPQ
945, Ave Wolfe
Quebec, QC
Canada, G1V 5B3
Phone: (418) 650-5115 Ext. 5254
Fax : (418) 654-2148
E-mail : [email protected]
http://www.inspq.qc.a/ctq
AMAP Ring Test for Persistent Organic
Pollutants in Human Serum
TABLE OF CONTENTS
PFHxA
77
PFHxS
80
PFNA
83
PFOA
86
PFOS
89
PFUdA
92
Total Cholesterol
95
Total lipids
98
Toxaphene Parlar # 26
101
Toxaphene Parlar # 50
104
trans-nonachlor
107
Triglycerides
110
ASSIGNED VALUES
113
GROUPING OF ANALYTICAL METHODS FOR STATISTICS
115
Centre de toxicologie/INSPQ
945, Ave Wolfe
Quebec, QC
Canada, G1V 5B3
Phone: (418) 650-5115 Ext. 5254
Fax : (418) 654-2148
E-mail : [email protected]
http://www.inspq.qc.a/ctq
AMAP Ring Test for Persistent Organic
Pollutants in Human Serum
INTRODUCTION
Dear AMAP participants:
This report includes the results and performance evaluations of round 2014-01.
Participating laboratories are identified only by their unique subscription number.
Identity of participants will be kept strictly confidential by the AMAP organizer.
For this PT exercise, all analytes meet the homogeneity criteria as per ISO/CEI 17043
and 13528 guidelines with the exception of heptachlor in materials AM-S-W1401,
AM-S-W1402 and AM-S-W1403. A note concerning the homogeneity of heptachlor has
been included in the corresponding section.
A study had been previously performed to demonstrate that all the analytes are stable
for the duration of the PT exercise and meet the stability criteria according to ISO/CEI
17043 and 13528 guidelines.
Please note that the appendices containing statistical approaches are no longer
included in the reports. You will find them within the “Participant’s Guide”.
We are available to assist you at any time. If you have any questions or concerns
regarding our program, do not hesitate to contact us. Your comments help us enhance
the quality of our schemes.
Best regards,
David Bisson, M.Sc. Chemist
Programs Coordinator
External Quality Assessment Schemes and Reference Materials
Centre de toxicologie du Québec / INSPQ
Tel.: (418) 650-5115, extension 4649
E-mail: [email protected]
Web Site: www.inspq.qc.ca/CTQ/paqe
Centre de toxicologie/INSPQ
945, Ave Wolfe
Québec, QC
Canada, G1V 5B3
Phone: (418) 650-5115 Ext. 5254
Fax : (418) 654-2148
E-mail : [email protected]
http://www.inspq.qc.ca/ctq
1
Individual results
Serum Dieldrin (µg/L)
Round #2014-01
Participant
AM-S-W1401
z’-score
AM-S-W1402
z’-score
AM-S-W1403
z’-score
Method
754
1.40
0.07
0.238
4.23
1.28
0.00
GC
1042
1.38
0.00
0.0965
-0.30
1.23
-0.20
GC-MS CI
2446
1.59
0.71
0.0700
-1.15
1.34
0.23
GC-MS EI
4336
1.13
-0.84
LL
---
1.24
-1.30
4.34
-1.71
ND
8559
59.8
-0.70
1.52
0.05
5.59
-0.07
ND
8916
60.8
-0.59
1.33
-0.87
5.18
-0.61
GC
9301
79.7
1.42
1.88
1.79
6.43
1.04
GC-MS EI
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
AM-S-W1401
66.4*
3.33
8.77
47.6 - 85.2
Accepted
---
AM-S-W1402
1.51
0.0545
0.199
1.10 - 1.92
Accepted
---
AM-S-W1403
5.64
0.159
0.745
4.12 - 7.16
Accepted
---
The assigned value is outside the concentration range of our scope of accreditation.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
20
Statistics
Serum p,p'-DDE (µg/L)
All methods
AM-S-W1401
AM-S-W1402
16
17
17
Robust mean Algo A
66.4
1.51
5.64
Robust STDev
10.7
0.180
0.523
Median
65.6
1.50
5.59
STDev from MAD
9.62
0.163
0.534
Arithmetic mean
66.2
1.52
5.62
STDev
10.5
0.199
0.559
CV or Variability
16.1%
11.9%
9.3%
AM-S-W1401
AM-S-W1402
AM-S-W1403
3
3
3
Robust mean Algo A
74.6
1.58
5.68
Robust STDev
1.87
0.150
0.526
Median
75.0
1.61
5.78
STDev from MAD
1.48
0.119
0.460
Arithmetic mean
70.6
1.54
5.68
STDev
8.48
0.190
0.464
CV or Variability
2.5%
9.5%
9.3%
AM-S-W1401
AM-S-W1402
AM-S-W1403
N
GC
N
GC-MS EI
N
AM-S-W1403
4
4
4
Robust mean Algo A
79.4
1.62
6.14
Robust STDev
4.08
0.175
0.588
Median
79.6
1.60
6.22
STDev from MAD
3.13
0.145
0.489
Arithmetic mean
73.6
1.64
6.13
STDev
14.9
0.183
0.541
CV or Variability
5.1%
10.8%
9.6%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
21
Distribution
Serum p,p'-DDE (µg/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
22
Individual results
Serum p,p'-DDT (µg/L)
Round #2014-01
Participant
AM-S-W1401
z’-score
AM-S-W1402
z’-score
AM-S-W1403
z’-score
748
0.396
0.24
0.604
-0.21
0.861
0.34
Method
ND
754
0.389
0.18
0.588
-0.30
0.775
-0.10
GC
1003
0.361
-0.03
0.669
0.17
0.802
0.04
GC-MS-MS
1042
0.349
-0.12
0.675
0.20
0.822
0.14
GC-MS CI
2446
0.290
-0.57
0.540
-0.58
0.680
-0.58
GC-MS EI
2968
0.342
-0.18
0.693
0.31
0.825
0.16
GC-MS EI
4336
| File Type | application/pdf |
| Author | David Bisson |
| File Modified | 2014-04-11 |
| File Created | 2014-04-11 |