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pdfINTERLABORATORY COMPARISON PROGRAM
FOR METALS IN BIOLOGICAL MATRICES
(PCI)
Centre de toxicologie/INSPQ
REPORT FOR ROUND:
2014-01
PTMS SHIPPING DATE:
2014-01-20
DATE OF PUBLICATION:
2014-03-19
945, Ave Wolfe
Quebec, QC
Canada, G1V 5B3
Phone: (418) 650-5115 Ext. 5254
Fax : (418) 654-2148
E-mail : [email protected]
http://www.inspq.qc.a/ctq
Interlaboratory Comparison Program for Metals in
Biological Matrices (PCI)
TABLE OF CONTENTS
INTRODUCTION
1
BLOOD
Cadmium
2
Lead
5
Mercury
9
SERUM
Aluminium
12
Copper
15
Manganese
18
Selenium
21
Zinc
24
URINE
Cadmium
27
Chromium
30
Copper
33
Fluoride
36
Inorganic arsenic
39
Iodide
42
Lead
45
Mercury
48
Selenium
51
Total arsenic
54
Zinc
57
ASSIGNED VALUES
60
GROUPING OF ANALYTICAL METHODS FOR STATISTICS
61
Centre de toxicologie/INSPQ
945, Ave Wolfe
Quebec, QC
Canada, G1V 5B3
Phone: (418) 650-5115 Ext. 5254
Fax : (418) 654-2148
E-mail : [email protected]
http://www.inspq.qc.a/ctq
Interlaboratory Comparison Program for Metals in
Biological Matrices (PCI)
INTRODUCTION
Dear PCI participants:
This report includes the results and performance evaluations of round 2014-01.
Participating laboratories are identified only by their unique subscription number.
Identity of participants will be kept strictly confidential by the PCI organizer.
All analytes meet the homogeneity criteria as per ISO/CEI 17043 and 13528
guidelines.
A study had been previously performed to demonstrate that all the analytes are
stable for the duration of the PT exercise and meet the stability criteria according
to ISO/CEI 17043 and 13528 guidelines.
Please note that the appendices containing statistical approaches are no longer
included in the reports. You will find them within the “Participant’s Guide”.
We are available to assist you at any time. If you have any questions or concerns
regarding our program, do not hesitate to contact us. Your comments help us
enhance the quality of our schemes.
Best regards,
David Bisson, M.Sc. Chemist
Program Coordinators
External Quality Assessment Schemes and Reference Materials
Centre de toxicologie du Québec / INSPQ
Tel.: (418) 650-5115, extension 4649
E-mail: [email protected]
Web Site: www.inspq.qc.ca/CTQ/paqe
Centre de toxicologie/INSPQ
945, Ave Wolfe
Quebec, QC
Canada, G1V 5B3
Phone: (418) 650-5115 Ext. 5254
Fax : (418) 654-2148
E-mail : [email protected]
http://www.inspq.qc.a/ctq
1
Individual results
Blood Cadmium (nmol/L)
Round #2014-01
Participant
PC-B-C1401
z’-score
PC-B-C1402
z’-score
PC-B-C1403
z’-score
Method
176
7.12
-1.01
98.7
-0.60
22.2
-0.35
ICP-MS
194
10.1
0.70
113
1.03
29.9
2.43
ND
217
8.27
-0.35
103
-0.14
21.4
-0.64
ICP-MS
323
11.0
1.22
88.0
-1.83
22.0
-0.43
GFAAS
744
11.0
1.23
93.9
-1.15
25.1
0.69
ND
747
8.25
-0.36
101
-0.34
22.0
-0.43
ICP-MS
1095
9.00
0.07
114
1.14
24.0
0.29
ICP-MS (C/R)
1109
10.7
1.03
117
1.43
27.6
1.59
ND
1188
9.87
0.57
103
-0.11
24.1
0.33
ICP-MS (C/R)
1418
8.63
-0.14
107
0.31
23.8
0.20
ICP-MS (C/R)
1865
8.45
-0.25
108
0.42
22.9
-0.12
ICP-MS (C/R)
2305
98.6
51.61
2.19
-11.64
6.67
-5.99
ND
2991
8.27
-0.35
113
1.08
27.2
1.46
ND
3187
8.01
-0.50
103
-0.11
21.9
-0.47
ICP-MS
3211
6.10
-1.60
98.7
-0.61
19.9
-1.20
GFAAS
3215
7.10
-1.02
104
0.00
26.8
1.30
GFAAS
3248
9.70
0.47
74.5
-3.37
35.3
4.39
GFAAS
3853
11.5
1.51
105
0.15
25.1
0.70
ICP-MS
4708
8.30
-0.33
106
0.23
22.6
-0.22
ICP-MS
4953
8.10
-0.45
107
0.31
22.2
-0.38
ICP-MS
5591
7.80
-0.62
97.8
-0.71
22.3
-0.33
ICP-MS
5654
9.43
0.32
92.0
-1.37
23.0
-0.06
ICP-MS (C/R)
5691
9.00
0.07
112
0.91
24.0
0.29
ICP-MS
6511
8.90
0.01
104
0.01
22.2
-0.35
ND
6545
4.14
-2.73
71.5
-3.71
20.8
-0.87
ICP-MS
6689
12.4
2.00
113
1.00
26.2
1.07
ND
6794
9.70
0.47
95.0
-1.03
23.5
0.10
GFAAS
6858
4.55
-2.49
105
0.13
18.4
-1.74
ICP-MS
7760
8.60
-0.16
108
0.48
25.2
0.73
ICP-MS
9777
11.1
1.29
115
1.30
21.9
-0.45
GFAAS
PC-B-C1401
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
8.88
0.382
1.70
5.40 - 12.4
Accepted
---
PC-B-C1402
104
1.98
8.51
86.5 - 121
Accepted
---
PC-B-C1403
23.2
0.440
2.72
17.7 - 28.7
Accepted
---
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
2
Statistics
Blood Cadmium (nmol/L)
All methods
PC-B-C1401
PC-B-C1402
29
29
30
Robust mean Algo A
8.88
104
23.2
Robust STDev
1.64
8.55
1.93
Median
8.63
104
23.0
STDev from MAD
1.58
7.98
1.63
Arithmetic mean
8.80
102
23.3
STDev
1.89
10.9
4.51
CV or Variability
18.5%
8.2%
8.3%
PC-B-C1401
PC-B-C1402
PC-B-C1403
6
6
6
Robust mean Algo A
9.21
96.6
23.5
Robust STDev
2.17
14.1
3.18
Median
9.70
96.9
22.7
STDev from MAD
2.02
11.9
2.70
Arithmetic mean
9.12
95.9
24.9
STDev
2.07
14.0
5.59
CV or Variability
23.5%
14.6%
13.5%
PC-B-C1401
PC-B-C1402
PC-B-C1403
N
Graphite furnace-AAS
N
ICP-MS
N
PC-B-C1403
12
12
12
Robust mean Algo A
8.10
104
22.2
Robust STDev
0.701
4.70
1.04
Median
8.17
104
22.2
STDev from MAD
0.595
4.26
0.860
Arithmetic mean
7.80
102
22.3
STDev
1.93
10.3
1.86
CV or Variability
8.6%
4.5%
4.7%
PC-B-C1401
PC-B-C1402
PC-B-C1403
ICP-MS (collision/reaction cell)
N
5
5
5
Robust mean Algo A
9.08
106
23.6
Robust STDev
0.659
6.56
0.603
Median
9.00
107
23.8
STDev from MAD
0.637
5.56
0.516
Arithmetic mean
9.08
105
23.6
STDev
0.581
8.12
0.565
CV or Variability
7.3%
6.2%
2.6%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
3
Distribution
Blood Cadmium (nmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
4
Individual results
Blood Lead (µmol/L)
Round #2014-01
Participant
PC-B-L1401
z’-score
PC-B-L1402
z’-score
PC-B-L1403
z’-score
Method
194
1.06
-2.74
0.307
0.44
2.89
-3.42
ND
217
1.39
0.74
0.300
0.18
4.20
1.15
ICP-MS
226
1.28
-0.43
0.285
-0.38
3.72
-0.54
ICP-MS
317
1.37
0.53
0.299
0.15
3.75
-0.42
GFAAS
323
1.35
0.36
0.392
3.58
3.21
-2.30
GFAAS
387
1.31
-0.06
0.275
-0.74
3.71
-0.57
GFAAS
636
5.56
44.61
0.330
1.29
4.15
0.98
ICP-MS
744
1.57
2.64
0.316
0.78
3.96
0.32
ND
747
1.32
0.00
0.299
0.15
3.88
0.03
ICP-MS
1095
1.38
0.63
0.300
0.18
4.33
1.60
GFAAS
1109
0.138
-12.44
0.0304
-9.76
0.411
-12.07
ND
1188
1.26
-0.63
0.280
-0.56
3.61
-0.91
ICP-MS (C/R)
1418
1.31
-0.10
0.300
0.19
4.10
0.82
ND
1761
1.33
0.09
0.268
-0.98
3.78
-0.30
GFAAS
1855
1.29
-0.28
0.290
-0.20
4.03
0.54
ICP-MS
1865
1.31
-0.08
0.304
0.33
3.85
-0.08
ICP-MS (C/R)
2305
4.43
32.72
1.55
46.29
0.0500
-13.32
ND
2397
1.29
-0.34
0.275
-0.74
3.73
-0.51
GFAAS
2516
1.55
2.40
0.368
2.69
4.70
2.88
GFAAS
2580
1.31
-0.11
0.220
-2.77
3.72
-0.52
GFAAS
2629
1.45
1.37
0.330
1.29
4.36
1.71
ICP-MS (C/R)
2635
1.42
1.05
0.300
0.18
4.25
1.33
ND
2907
1.12
-2.11
0.248
-1.75
3.29
-2.03
ICP-MS
2937
1.36
0.42
0.319
0.89
---
---
GFAAS
2982
1.10
-2.36
0.236
-2.18
2.79
-3.76
GFAAS
2991
1.23
-0.93
0.311
0.58
3.23
-2.22
ND
3150
1.38
0.63
0.300
0.18
4.13
0.91
GFAAS
3167
1.37
0.53
0.340
1.66
4.26
1.36
GFAAS
3187
1.35
0.32
0.300
0.18
4.02
0.52
ICP-MS
3211
1.38
0.63
0.290
-0.18
3.85
-0.07
GFAAS
3215
1.30
-0.21
0.280
-0.55
>LL
---
GFAAS
3248
1.25
-0.74
0.290
-0.18
3.96
0.31
GFAAS
3423
1.16
-1.73
0.294
-0.05
3.62
-0.86
GFAAS
3513
1.38
0.63
0.330
1.29
3.94
0.24
ICP-MS
3853
1.36
0.42
0.320
0.92
4.21
1.19
ICP-MS
3970
1.50
1.85
0.280
-0.56
4.39
1.80
GFAAS
4082
1.38
0.63
0.287
-0.30
4.04
0.59
ICP-MS
4090
1.25
-0.74
0.270
-0.92
3.84
-0.10
ICP-MS (C/R)
4708
1.32
0.00
0.297
0.07
3.93
0.21
ICP-MS
4953
1.40
0.84
0.275
-0.73
4.09
0.78
GFAAS
5291
1.18
-1.47
0.230
-2.40
3.85
-0.07
ND
5432
1.31
-0.13
0.372
2.83
4.62
2.63
GFAAS
5491
1.35
0.34
0.289
-0.22
3.76
-0.37
GFAAS
5556
1.35
0.33
0.345
1.83
3.85
-0.08
GFAAS
5591
1.22
-1.05
0.280
-0.55
3.64
-0.80
ICP-MS
5654
1.26
-0.58
0.301
0.23
3.71
-0.55
ICP-MS (C/R)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
5
Individual results
Blood Lead (µmol/L)
Round #2014-01
Participant
PC-B-L1401
z’-score
PC-B-L1402
z’-score
PC-B-L1403
z’-score
Method
5691
1.32
0.00
0.290
-0.18
3.85
-0.07
ICP-MS
6200
1.31
-0.07
0.294
-0.03
3.93
0.21
ICP-MS
6276
1.28
-0.38
0.280
-0.56
3.64
-0.81
ICP-MS
6511
1.29
-0.33
0.295
0.01
4.00
0.44
ND
6545
1.28
-0.42
0.280
-0.55
3.62
-0.87
ICP-MS
6794
1.39
0.77
0.302
0.24
4.46
2.06
GFAAS
7111
1.30
-0.17
0.289
-0.22
3.82
-0.18
ICP-MS
7269
1.33
0.11
0.330
1.29
3.76
-0.38
GFAAS
7311
1.33
0.11
0.300
0.18
3.88
0.03
ICP-MS
7760
1.24
-0.82
0.274
-0.79
4.09
0.76
ICP-MS
7804
0.813
-5.33
0.231
-2.35
3.85
-0.06
ND
7932
1.25
-0.74
0.315
0.74
3.14
-2.56
GFAAS
8701
1.22
-1.05
0.270
-0.92
3.55
-1.12
ND
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-B-L1401
1.32
0.0137
0.0937
1.13 - 1.51
Rejected
---
PC-B-L1402
0.295
0.00399
0.0268
0.241 - 0.349
Rejected
---
PC-B-L1403
3.87
0.0518
0.282
3.30 - 4.44
Accepted
---
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
6
Statistics
Blood Lead (µmol/L)
All methods
PC-B-L1401
PC-B-L1402
60
59
56
1.32
0.295
3.87
0.0848
0.0245
0.310
1.31
0.295
3.85
0.0838
0.0229
0.297
Arithmetic mean
1.41
0.313
3.80
STDev
0.705
0.170
0.594
CV or Variability
6.4%
8.3%
8.0%
PC-B-L1401
PC-B-L1402
PC-B-L1403
24
24
22
1.34
0.300
3.89
0.0583
0.0333
0.393
1.35
0.296
3.82
0.0585
0.0316
0.348
N
Robust mean Algo A
Robust STDev
Median
STDev from MAD
Graphite furnace-AAS
N
Robust mean Algo A
Robust STDev
Median
STDev from MAD
Arithmetic mean
STDev
1.34
0.302
3.89
0.0928
0.0405
0.471
4.3%
11.1%
10.1%
PC-B-L1401
PC-B-L1402
PC-B-L1403
CV or Variability
ICP-MS
N
19
19
19
1.32
0.292
3.91
0.0594
0.0143
0.196
Robust mean Algo A
Robust STDev
PC-B-L1403
Median
1.32
0.290
3.93
STDev from MAD
0.0593
0.0148
0.166
Arithmetic mean
1.53
0.293
3.89
STDev
0.978
0.0194
0.232
CV or Variability
4.5%
4.9%
5.0%
PC-B-L1401
PC-B-L1402
PC-B-L1403
ICP-MS (collision/reaction cell)
N
6
5
5
1.27
0.297
3.83
0.0163
0.0265
0.220
Robust mean Algo A
Robust STDev
Median
1.26
0.301
3.84
STDev from MAD
0.0141
0.0315
0.191
Arithmetic mean
1.30
0.297
3.87
0.0765
0.0233
0.289
1.3%
8.9%
5.7%
STDev
CV or Variability
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
7
Distribution
Blood Lead (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
8
Individual results
Blood Mercury (nmol/L)
Round #2014-01
Participant
PC-B-M1401
z’-score
PC-B-M1402
z’-score
PC-B-M1403
z’-score
Method
176
19.9
-0.32
<19,9
---
419
1.22
ICP-MS
217
14.0
-2.51
12.0
2.33
451
1.92
ICP-MS
323
21.0
0.07
8.00
-0.87
328
-0.76
CV
428
22.9
0.79
9.77
0.55
318
-0.99
ICP-MS
744
19.7
-0.42
8.59
-0.40
388
0.55
ND
ICP-MS
747
20.6
-0.07
8.73
-0.29
353
-0.22
1095
19.0
-0.67
8.00
-0.87
354
-0.20
CV
1109
79.9
21.84
123
90.90
357
-0.13
ND
1156
39.9
7.07
7.26
-1.47
384
0.45
ND
1188
20.3
-0.18
8.38
-0.57
361
-0.04
ICP-MS (C/R)
1418
18.9
-0.70
8.48
-0.49
306
-1.25
ND
1865
22.7
0.71
9.87
0.63
384
0.47
CV
ICP-MS
2907
LL
---
GFAAS
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-S-A1401
1.46
0.0425
0.200
1.05 - 1.87
Accepted
---
PC-S-A1402
0.643
0.0279
0.107
0.421 - 0.865
Accepted
---
PC-S-A1403
6.27
0.180
0.744
4.74 - 7.80
Accepted
---
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
12
Statistics
Serum Aluminium (µmol/L)
All methods
PC-S-A1401
PC-S-A1402
31
31
31
Robust mean Algo A
1.46
0.643
6.27
Robust STDev
0.189
0.124
0.803
Median
1.45
0.660
6.31
STDev from MAD
0.200
0.118
0.838
Arithmetic mean
1.47
0.629
6.16
STDev
0.212
0.142
1.16
CV or Variability
13.0%
19.3%
12.8%
PC-S-A1401
PC-S-A1402
PC-S-A1403
14
14
13
Robust mean Algo A
1.49
0.640
6.43
Robust STDev
0.176
0.142
0.886
Median
1.52
0.660
6.46
STDev from MAD
0.162
0.153
0.863
Arithmetic mean
1.47
0.637
6.37
STDev
0.188
0.130
0.905
CV or Variability
11.8%
22.3%
13.8%
PC-S-A1401
PC-S-A1402
PC-S-A1403
N
Graphite furnace-AAS
N
ICP-MS
N
7
7
7
1.43
0.624
6.06
0.0646
0.134
0.536
Robust mean Algo A
Robust STDev
PC-S-A1403
Median
1.45
0.593
6.09
STDev from MAD
0.0525
0.129
0.512
Arithmetic mean
1.43
0.625
6.06
0.0995
0.119
0.473
4.5%
21.4%
8.9%
PC-S-A1401
PC-S-A1402
PC-S-A1403
STDev
CV or Variability
ICP-MS (collision/reaction cell)
N
4
4
5
Robust mean Algo A
1.37
0.598
6.26
Robust STDev
0.150
0.0365
0.821
Median
1.35
0.597
6.25
STDev from MAD
0.124
0.0278
0.628
Arithmetic mean
1.52
0.651
5.67
STDev
0.417
0.133
2.46
CV or Variability
10.9%
6.1%
13.1%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
13
Distribution
Serum Aluminium (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
14
Individual results
Serum Copper (µmol/L)
Round #2014-01
Participant
PC-S-E1401
z’-score
PC-S-E1402
z’-score
PC-S-E1403
z’-score
217
17.9
1.06
28.0
0.56
10.8
1.37
Method
FAAS
226
17.6
0.80
27.7
0.35
9.47
-0.24
ICP-MS (C/R)
387
18.7
1.76
28.2
0.68
10.0
0.45
GFAAS
428
17.9
1.02
29.3
1.35
10.1
0.49
ICP-MS (C/R)
636
15.5
-1.03
24.7
-1.48
8.61
-1.29
ICP-MS
744
16.4
-0.31
26.9
-0.10
9.89
0.27
ND
747
16.8
0.09
27.4
0.19
9.73
0.07
ICP-MS
1095
17.2
0.44
28.0
0.56
9.70
0.04
FAAS
1109
16.8
0.09
27.9
0.53
9.62
-0.06
ND
1188
17.0
0.25
27.6
0.31
9.73
0.07
ICP-MS (C/R)
1300
16.8
0.12
27.5
0.27
9.60
-0.09
FAAS
1855
15.8
-0.75
25.8
-0.80
9.77
0.12
ICP-MS
2305
15.6
-1.01
9.35
-11.05
25.2
18.81
ND
2516
11.1
-4.92
19.4
-4.79
6.90
-3.37
ND
2580
17.6
0.79
29.0
1.18
10.5
1.01
FAAS
2763
16.7
0.00
27.0
-0.06
9.52
-0.18
ICP-MS (C/R)
2907
16.4
-0.31
26.9
-0.11
9.43
-0.30
ICP-MS
2982
16.8
0.12
26.5
-0.39
9.43
-0.30
FAAS
3150
16.6
-0.09
26.6
-0.31
9.10
-0.69
FAAS
3211
16.1
-0.53
26.4
-0.44
9.30
-0.45
FAAS
3423
16.1
-0.57
27.6
0.33
8.78
-1.09
FAAS
3513
17.3
0.53
28.6
0.93
10.2
0.64
ICP-MS
3773
19.2
2.18
30.3
2.02
11.4
2.13
ICP-MS (C/R)
3853
19.1
2.09
28.9
1.11
10.8
1.36
ICP-MS
4082
16.7
0.00
27.6
0.31
9.50
-0.21
ICP-MS
4090
16.1
-0.52
27.0
-0.08
8.90
-0.94
ICP-MS (C/R)
4953
17.8
0.95
29.1
1.26
10.4
0.87
ICP-MS
5291
17.7
0.88
29.3
1.37
10.5
1.01
ND
5556
17.0
0.26
26.0
-0.71
10.4
0.87
FAAS
5591
17.2
0.44
28.7
1.00
9.80
0.16
GFAAS
5596
14.8
-1.71
24.6
-1.56
8.88
-0.95
ICP-MS (C/R)
5654
15.4
-1.14
25.0
-1.33
8.63
-1.26
ICP-MS (C/R)
5691
15.9
-0.70
24.8
-1.43
9.30
-0.45
ICP-MS
5881
17.0
0.26
27.2
0.06
9.76
0.11
ICP-MS (C/R)
5955
16.9
0.18
27.7
0.37
9.69
0.02
ND
6511
16.4
-0.31
27.0
-0.04
9.13
-0.66
ND
6711
16.2
-0.47
26.1
-0.65
9.73
0.08
ND
7311
16.4
-0.24
27.2
0.08
9.79
0.15
ICP-MS
7804
24.4
6.73
19.0
-5.05
6.35
-4.03
ND
8376
18.8
1.84
31.8
2.92
11.3
1.98
FAAS
8454
16.4
-0.26
26.1
-0.62
9.71
0.05
FAAS
8981
15.9
-0.70
24.9
-1.37
9.43
-0.29
ND
9677
14.6
-1.86
23.8
-2.06
8.34
-1.61
ICP-OES
9759
15.9
-0.71
27.0
-0.07
9.65
-0.03
FAAS
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-S-E1401
16.7
0.193
1.12
14.4 - 19.0
Rejected
---
PC-S-E1402
27.1
0.315
1.57
23.9 - 30.3
Rejected
---
PC-S-E1403
9.67
0.120
0.814
8.02 - 11.3
Rejected
---
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
15
Statistics
Serum Copper (µmol/L)
All methods
PC-S-E1401
PC-S-E1402
44
44
44
Robust mean Algo A
16.7
27.1
9.67
Robust STDev
1.02
1.67
0.636
Median
16.8
27.1
9.70
STDev from MAD
1.00
1.53
0.572
Arithmetic mean
16.8
26.5
9.93
STDev
1.77
3.51
2.52
CV or Variability
6.1%
6.2%
6.6%
PC-S-E1401
PC-S-E1402
PC-S-E1403
12
12
12
Robust mean Algo A
16.9
27.3
9.80
Robust STDev
0.823
1.19
0.730
Median
16.8
27.3
9.67
STDev from MAD
0.872
1.14
0.702
Arithmetic mean
16.9
27.5
9.85
STDev
0.847
1.62
0.742
CV or Variability
4.9%
4.3%
7.4%
PC-S-E1401
PC-S-E1402
PC-S-E1403
N
Flame-AAS
N
ICP-MS
N
PC-S-E1403
10
10
10
Robust mean Algo A
16.7
27.1
9.76
Robust STDev
0.959
1.79
0.593
Median
16.6
27.3
9.75
STDev from MAD
1.03
2.07
0.574
Arithmetic mean
16.8
27.1
9.75
STDev
1.06
1.58
0.611
CV or Variability
5.8%
6.6%
6.1%
PC-S-E1401
PC-S-E1402
PC-S-E1403
ICP-MS (collision/reaction cell)
N
9
9
9
Robust mean Algo A
16.8
27.2
9.51
Robust STDev
1.38
0.884
0.724
Median
17.0
27.2
9.52
STDev from MAD
1.29
0.700
0.818
Arithmetic mean
16.8
27.3
9.60
STDev
1.33
1.82
0.833
CV or Variability
8.2%
3.2%
7.6%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
16
Distribution
Serum Copper (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
17
Individual results
Serum Manganese (nmol/L)
Round #2014-01
Participant
PC-S-G1401
z’-score
PC-S-G1402
z’-score
PC-S-G1403
z’-score
Method
217
36.0
1.49
17.0
2.78
58.0
0.59
ICP-MS
323
28.0
-0.46
8.00
-1.77
49.0
-0.62
GFAAS
ICP-MS
747
29.3
-0.15
13.0
0.76
54.6
0.13
1109
34.6
1.14
17.3
2.92
71.0
2.34
ND
1188
31.1
0.29
11.5
0.00
55.5
0.26
ICP-MS (C/R)
2629
19.7
-2.50
10.9
-0.29
31.3
-3.00
GFAAS
2763
26.7
-0.78
9.94
-0.79
46.1
-1.01
ICP-MS (C/R)
2978
32.2
0.57
11.7
0.09
62.3
1.17
ICP-MS (C/R)
6511
29.7
-0.06
11.5
-0.02
52.4
-0.16
ND
8376
28.0
-0.46
9.10
-1.21
47.3
-0.85
GFAAS
9759
30.9
0.25
10.9
-0.29
56.4
0.38
GFAAS
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-S-G1401
29.9
1.09
3.95
21.7 - 38.1
Accepted
---
PC-S-G1402
11.5
0.912
1.76
7.54 - 15.5
Rejected
---
PC-S-G1403
53.6
3.03
6.78
38.8 - 68.4
Accepted
---
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
18
Statistics
Serum Manganese (nmol/L)
All methods
PC-S-G1401
PC-S-G1402
11
11
11
Robust mean Algo A
29.9
11.5
53.6
Robust STDev
2.90
2.42
8.03
Median
29.7
11.5
54.6
STDev from MAD
2.48
2.27
8.30
Arithmetic mean
29.7
11.9
53.1
STDev
4.35
2.92
10.1
CV or Variability
9.7%
21.1%
15.0%
PC-S-G1401
PC-S-G1402
PC-S-G1403
4
4
4
Robust mean Algo A
27.9
9.74
47.7
Robust STDev
2.87
1.63
8.57
Median
28.0
10.0
48.2
STDev from MAD
2.18
1.35
6.75
Arithmetic mean
26.7
9.74
46.0
STDev
4.87
1.44
10.6
CV or Variability
10.3%
16.8%
18.0%
PC-S-G1401
PC-S-G1402
PC-S-G1403
N
Graphite furnace-AAS
N
ICP-MS (collision/reaction cell)
N
PC-S-G1403
3
3
3
Robust mean Algo A
30.6
11.4
54.6
Robust STDev
2.09
0.348
9.20
Median
31.1
11.5
55.5
STDev from MAD
1.66
0.276
10.0
Arithmetic mean
30.0
11.0
54.6
STDev
2.92
0.959
8.11
CV or Variability
6.8%
3.0%
16.8%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
19
Distribution
Serum Manganese (nmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
20
Individual results
Serum Selenium (µmol/L)
Round #2014-01
Participant
PC-S-E1401
z’-score
PC-S-E1402
z’-score
PC-S-E1403
z’-score
217
1.95
1.71
2.39
0.96
1.50
1.23
Method
ICP-MS
226
1.77
0.55
2.27
0.34
1.34
0.02
ICP-MS (C/R)
428
1.65
-0.21
2.20
0.02
1.32
-0.18
ICP-MS (C/R)
636
1.61
-0.44
2.17
-0.15
1.30
-0.31
ICP-MS
747
1.56
-0.76
2.14
-0.30
1.28
-0.46
ICP-MS
1095
1.58
-0.63
2.09
-0.55
1.40
0.46
GFAAS
1109
1.82
0.88
2.27
0.34
1.61
2.04
ND
1188
1.84
1.01
2.43
1.16
1.47
1.00
ICP-MS (C/R)
1300
1.89
1.31
2.20
0.02
1.29
-0.37
HG-AAS
1855
1.62
-0.37
2.28
0.40
1.47
0.99
ICP-MS (C/R)
2305
1.75
0.44
1.90
-1.51
1.33
-0.08
ND
2516
1.87
1.20
2.50
1.51
1.59
1.92
ND
2763
1.59
-0.57
2.08
-0.61
1.23
-0.84
ICP-MS (C/R)
3150
1.58
-0.63
2.11
-0.45
1.40
0.46
GFAAS
3513
1.50
-1.14
1.92
-1.41
1.25
-0.69
ICP-MS (C/R)
3773
1.74
0.36
2.34
0.71
1.35
0.11
ICP-MS (C/R)
3853
1.83
0.95
2.28
0.40
1.41
0.54
ICP-MS (C/R)
4082
1.70
0.13
2.33
0.66
1.33
-0.08
ICP-MS
4590
1.40
-1.79
1.99
-1.06
1.11
-1.78
GFAAS
4953
1.60
-0.53
2.10
-0.49
1.24
-0.80
ICP-MS (C/R)
5291
1.53
-0.95
2.18
-0.10
1.35
0.08
ND
5556
1.38
-1.89
2.05
-0.75
1.24
-0.78
GFAAS
5596
1.75
0.42
2.37
0.84
1.38
0.27
ICP-MS (C/R)
5654
1.86
1.14
2.39
0.98
1.38
0.31
ICP-MS (C/R)
5691
1.53
-0.95
1.92
-1.41
1.18
-1.23
ICP-MS
5881
1.68
0.00
2.22
0.10
1.32
-0.15
ICP-MS (C/R)
5955
1.63
-0.32
2.19
-0.05
1.30
-0.31
ND
6511
1.75
0.43
2.29
0.44
1.32
-0.16
ND
6545
1.74
0.38
2.27
0.35
1.37
0.23
ICP-MS
7311
1.86
1.14
2.43
1.16
1.43
0.69
ICP-MS
7804
1.40
-1.77
1.80
-2.02
1.23
-0.84
ND
8376
1.63
-0.33
2.16
-0.22
1.38
0.30
GFAAS
8454
1.59
-0.57
2.05
-0.76
1.32
-0.15
GFAAS
9759
1.84
1.02
2.40
1.01
1.56
1.67
GFAAS
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-S-E1401
1.68
0.0329
0.155
1.36 - 2.00
Accepted
---
PC-S-E1402
2.20
0.0379
0.195
1.80 - 2.60
Accepted
---
PC-S-E1403
1.34
0.0202
0.129
1.08 - 1.60
Accepted
---
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
21
Statistics
Serum Selenium (µmol/L)
All methods
PC-S-E1401
PC-S-E1402
34
34
34
Robust mean Algo A
1.68
2.20
1.34
Robust STDev
0.153
0.177
0.0942
Median
1.66
2.20
1.34
STDev from MAD
0.141
0.176
0.0890
N
PC-S-E1403
Arithmetic mean
1.68
2.20
1.35
STDev
0.149
0.170
0.111
CV or Variability
9.1%
8.0%
7.0%
PC-S-E1401
PC-S-E1402
PC-S-E1403
7
7
7
1.57
2.09
1.36
0.0871
0.0714
0.107
1.58
2.09
1.38
0.0703
0.0593
0.0878
Graphite furnace-AAS
N
Robust mean Algo A
Robust STDev
Median
STDev from MAD
Arithmetic mean
1.57
2.12
1.34
STDev
0.155
0.134
0.142
CV or Variability
5.5%
3.4%
7.9%
PC-S-E1401
PC-S-E1402
PC-S-E1403
ICP-MS
N
7
7
7
Robust mean Algo A
1.71
2.25
1.34
Robust STDev
0.177
0.172
0.0917
Median
1.70
2.27
1.33
STDev from MAD
0.208
0.178
0.0742
Arithmetic mean
1.71
2.24
1.34
STDev
0.156
0.175
0.104
CV or Variability
10.4%
7.7%
6.9%
PC-S-E1401
PC-S-E1402
PC-S-E1403
ICP-MS (collision/reaction cell)
N
12
12
12
Robust mean Algo A
1.70
2.26
1.35
Robust STDev
0.128
0.132
0.0845
Median
1.71
2.27
1.35
STDev from MAD
0.148
0.120
0.0701
Arithmetic mean
1.70
2.24
1.35
STDev
0.114
0.147
0.0815
CV or Variability
7.5%
5.9%
6.3%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
22
Distribution
Serum Selenium (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
23
Individual results
Serum Zinc (µmol/L)
Round #2014-01
Participant
PC-S-E1401
z’-score
PC-S-E1402
z’-score
PC-S-E1403
z’-score
217
21.2
1.14
29.3
0.89
14.4
1.62
Method
FAAS
226
19.7
0.38
25.2
-0.62
13.0
0.48
ICP-MS (C/R)
428
19.6
0.30
28.4
0.54
12.9
0.43
ICP-MS (C/R)
636
17.3
-0.89
26.5
-0.15
12.0
-0.30
ICP-MS
744
17.5
-0.77
26.9
-0.01
11.4
-0.77
ND
747
19.0
0.00
27.1
0.07
12.3
-0.08
ICP-MS
1095
16.8
-1.15
24.2
-1.00
10.9
-1.21
FAAS
1109
21.4
1.26
29.0
0.80
14.1
1.38
ND
1188
19.0
-0.03
26.6
-0.11
12.5
0.08
ICP-MS (C/R)
1300
20.3
0.70
28.1
0.46
13.0
0.48
FAAS
1855
16.9
-1.11
24.1
-1.05
12.6
0.17
ICP-MS
2305
17.4
-0.86
24.8
-0.77
11.8
-0.52
ND
2516
19.6
0.31
28.6
0.63
13.2
0.64
ND
2580
19.2
0.10
27.3
0.15
12.6
0.16
FAAS
2763
18.3
-0.37
25.8
-0.41
11.8
-0.48
ICP-MS (C/R)
2907
20.4
0.73
26.9
-0.01
12.7
0.23
ICP-MS
2982
15.8
-1.66
23.3
-1.35
9.88
-2.03
FAAS
3150
18.9
-0.05
26.6
-0.11
12.1
-0.24
FAAS
3211
19.5
0.26
28.0
0.41
12.6
0.16
FAAS
3423
18.1
-0.45
27.0
0.05
11.9
-0.39
FAAS
3513
18.8
-0.10
27.7
0.30
12.2
-0.16
ICP-MS
3773
21.4
1.27
29.6
1.00
14.5
1.72
ICP-MS (C/R)
3853
21.4
1.28
28.5
0.61
13.7
1.01
ICP-MS
4082
19.2
0.10
27.9
0.37
12.3
-0.08
ICP-MS (C/R)
4090
18.0
-0.51
25.5
-0.54
11.1
-1.05
ICP-MS (C/R)
4953
20.5
0.77
28.8
0.71
13.5
0.89
ICP-MS
5291
22.9
2.04
32.2
1.97
15.0
2.10
ND
5556
18.8
-0.10
25.4
-0.57
11.9
-0.38
FAAS
5591
18.8
-0.10
25.8
-0.41
12.7
0.24
FAAS
5596
18.0
-0.51
25.7
-0.44
12.2
-0.19
ICP-MS (C/R)
5654
17.5
-0.78
25.3
-0.60
11.3
-0.88
ICP-MS (C/R)
5691
17.8
-0.63
24.6
-0.85
11.9
-0.40
ICP-MS
5881
19.2
0.12
27.4
0.19
12.4
0.02
ICP-MS (C/R)
5955
18.6
-0.21
26.7
-0.07
12.2
-0.16
ND
6511
19.2
0.09
27.1
0.07
12.1
-0.25
ND
7311
19.8
0.41
28.1
0.45
12.9
0.42
ICP-MS
7804
16.5
-1.31
21.1
-2.16
6.90
-4.43
ND
8376
20.0
0.54
28.5
0.61
13.4
0.82
FAAS
8454
17.4
-0.84
25.5
-0.52
12.0
-0.32
FAAS
8981
20.5
0.79
28.1
0.45
13.3
0.73
ND
9677
16.9
-1.10
24.2
-1.02
10.7
-1.40
ICP-OES
9759
21.1
1.07
29.8
1.08
14.3
1.51
FAAS
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-S-E1401
19.0
0.320
1.88
15.2 - 22.8
Accepted
---
PC-S-E1402
26.9
0.379
2.66
21.5 - 32.3
Accepted
---
PC-S-E1403
12.4
0.177
1.23
9.91 - 14.9
Accepted
---
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
24
Statistics
Serum Zinc (µmol/L)
All methods
PC-S-E1401
PC-S-E1402
42
42
42
Robust mean Algo A
19.0
26.9
12.4
Robust STDev
1.66
1.96
0.918
Median
19.0
27.0
12.4
STDev from MAD
1.65
2.12
0.841
Arithmetic mean
19.0
26.8
12.4
STDev
1.57
2.04
1.37
CV or Variability
8.7%
7.3%
7.4%
PC-S-E1401
PC-S-E1402
PC-S-E1403
13
13
13
Robust mean Algo A
19.0
26.9
12.5
Robust STDev
1.70
2.14
1.10
Median
18.9
27.0
12.6
STDev from MAD
1.67
2.21
1.00
Arithmetic mean
18.9
26.8
12.4
STDev
1.59
1.95
1.24
CV or Variability
9.0%
7.9%
8.8%
PC-S-E1401
PC-S-E1402
PC-S-E1403
N
Flame-AAS
N
ICP-MS
N
PC-S-E1403
9
9
9
Robust mean Algo A
19.1
27.0
12.6
Robust STDev
1.77
1.64
0.676
Median
19.0
27.1
12.6
STDev from MAD
2.07
1.50
0.612
Arithmetic mean
19.1
26.9
12.6
STDev
1.56
1.66
0.619
CV or Variability
9.3%
6.1%
5.4%
PC-S-E1401
PC-S-E1402
PC-S-E1403
ICP-MS (collision/reaction cell)
N
10
10
10
Robust mean Algo A
18.9
26.6
12.3
Robust STDev
1.06
1.43
0.875
Median
19.1
26.2
12.4
STDev from MAD
1.05
1.39
0.841
Arithmetic mean
19.0
26.7
12.4
STDev
1.13
1.51
0.971
CV or Variability
5.6%
5.4%
7.1%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
25
Distribution
Serum Zinc (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
26
Individual results
Urine Cadmium (nmol/L)
Round #2014-01
Participant
PC-U-D1401
z’-score
PC-U-D1402
z’-score
PC-U-D1403
z’-score
Method
217
91.6
-0.20
18.7
-0.30
64.1
2.42
ICP-MS
744
89.4
-0.51
16.0
-1.55
49.0
-0.84
ND
747
89.1
-0.55
19.3
0.00
46.8
-1.32
ICP-MS
1095
107
1.91
23.0
1.76
60.0
1.54
ICP-MS (C/R)
1109
99.2
0.84
20.1
0.38
60.8
1.70
ND
1418
93.9
0.12
19.7
0.21
53.6
0.16
ICP-MS (C/R)
1865
93.4
0.04
18.9
-0.21
61.3
1.82
ICP-MS (C/R)
2937
73.1
-2.75
13.2
-2.91
53.6
0.15
ICP-MS
2991
91.2
-0.26
21.5
1.06
50.2
-0.59
ND
3187
92.2
-0.12
18.6
-0.33
46.0
-1.50
ICP-MS
3211
94.6
0.21
17.5
-0.86
50.3
-0.56
GFAAS
3215
>LL
---
19.6
0.14
56.4
0.76
GFAAS
3423
87.9
-0.72
20.0
0.34
51.4
-0.32
GFAAS
3853
91.0
-0.29
16.0
-1.57
44.0
-1.93
ICP-MS
4466
84.9
-1.13
11.4
-3.78
41.2
-2.55
GFAAS
4708
93.4
0.04
19.3
0.00
52.2
-0.15
ICP-MS
4953
97.9
0.65
19.4
0.04
56.2
0.72
ICP-MS
5591
94.1
0.14
19.2
-0.05
50.4
-0.54
ICP-MS
5654
94.5
0.19
19.9
0.30
60.8
1.70
ICP-MS (C/R)
5691
93.0
-0.01
19.0
-0.14
54.0
0.24
ICP-MS
5881
93.4
0.04
19.7
0.21
53.2
0.06
ICP-MS (C/R)
6511
93.4
0.04
19.1
-0.08
56.9
0.87
ND
6545
50.0
-5.93
20.3
0.48
42.1
-2.34
ICP-MS
6689
96.2
0.42
19.7
0.17
49.4
-0.77
ND
6794
93.9
0.12
18.7
-0.29
54.0
0.24
GFAAS
6858
86.1
-0.96
17.4
-0.92
48.4
-0.98
ICP-MS
6920
99.0
0.81
21.4
1.00
53.5
0.13
ND
7760
101
1.14
20.5
0.57
61.2
1.80
ICP-MS
8701
101
1.02
19.4
0.06
52.5
-0.08
ND
9759
89.0
-0.57
22.2
1.40
48.9
-0.86
GFAAS
9777
638
74.95
4220
2002.08
845
171.79
GFAAS
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-U-D1401
93.1
1.06
7.18
78.6 - 108
Accepted
---
PC-U-D1402
19.3
0.254
2.09
15.1 - 23.5
Accepted
---
PC-U-D1403
52.9
1.35
4.40
43.7 - 62.1
Accepted
---
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
27
Statistics
Urine Cadmium (nmol/L)
All methods
PC-U-D1401
PC-U-D1402
29
30
30
Robust mean Algo A
93.1
19.3
52.9
Robust STDev
4.58
1.11
5.93
Median
93.4
19.3
52.9
STDev from MAD
4.09
0.991
5.47
Arithmetic mean
91.5
19.0
52.7
STDev
10.0
2.37
5.83
CV or Variability
4.9%
5.8%
11.2%
PC-U-D1401
PC-U-D1402
PC-U-D1403
5
6
6
Robust mean Algo A
90.1
19.0
51.0
Robust STDev
4.68
2.24
4.44
Median
89.0
19.1
50.9
STDev from MAD
5.99
1.87
3.76
Arithmetic mean
90.1
18.2
50.4
STDev
4.12
3.72
5.25
CV or Variability
5.2%
11.8%
8.7%
PC-U-D1401
PC-U-D1402
PC-U-D1403
N
Graphite furnace-AAS
N
ICP-MS
N
PC-U-D1403
12
12
12
Robust mean Algo A
91.5
19.0
51.4
Robust STDev
4.46
0.818
7.18
Median
91.9
19.1
51.3
STDev from MAD
3.71
0.682
6.99
Arithmetic mean
87.7
18.4
51.6
STDev
13.7
2.04
6.69
CV or Variability
4.9%
4.3%
14.0%
PC-U-D1401
PC-U-D1402
PC-U-D1403
ICP-MS (collision/reaction cell)
N
5
5
5
Robust mean Algo A
94.1
19.8
59.3
Robust STDev
0.837
0.330
2.27
Median
93.9
19.7
60.0
STDev from MAD
0.792
0.264
1.92
Arithmetic mean
96.4
20.3
57.8
STDev
5.92
1.59
4.01
CV or Variability
0.9%
1.7%
3.8%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
28
Distribution
Urine Cadmium (nmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
29
Individual results
Urine Chromium (nmol/L)
Round #2014-01
Participant
PC-U-B1401
z’-score
PC-U-B1402
z’-score
PC-U-B1403
z’-score
Method
176
23.1
0.17
235
-0.25
30.8
-0.51
ICP-MS (C/R)
744
17.1
-0.85
247
0.34
38.1
0.58
ND
747
21.7
-0.07
242
0.09
36.7
0.38
ICP-MS (C/R)
1095
28.0
1.01
245
0.23
36.0
0.27
GFAAS
1109
23.5
0.23
255
0.67
38.7
0.67
ND
1418
19.0
-0.52
223
-0.78
31.2
-0.46
ICP-MS (C/R)
1865
31.2
1.55
256
0.73
48.5
2.14
ICP-MS (C/R)
2982
LL
---
2.13
-0.04
>LL
---
GFAAS
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-U-R1401
4.01
0.0757
0.314
3.36 - 4.66
Accepted
---
PC-U-R1402
2.14
0.0320
0.170
1.79 - 2.49
Accepted
---
PC-U-R1403
14.6
0.205
1.13
12.3 - 16.9
Accepted
---
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
33
Statistics
Urine Copper (µmol/L)
All methods
PC-U-R1401
PC-U-R1402
27
28
27
Robust mean Algo A
4.01
2.14
14.6
Robust STDev
0.315
0.135
0.851
Median
4.01
2.15
14.7
STDev from MAD
0.280
0.141
0.742
14.7
N
PC-U-R1403
Arithmetic mean
4.02
2.11
STDev
0.440
0.193
1.25
CV or Variability
7.9%
6.3%
5.8%
PC-U-R1401
PC-U-R1402
PC-U-R1403
3
4
3
Robust mean Algo A
3.84
2.17
16.5
Robust STDev
0.909
0.199
0.959
Median
4.01
2.19
16.7
STDev from MAD
0.784
0.165
0.760
15.7
Graphite furnace-AAS
N
Arithmetic mean
3.84
2.03
STDev
0.802
0.438
2.29
CV or Variability
23.7%
9.2%
5.8%
PC-U-R1401
PC-U-R1402
PC-U-R1403
ICP-MS
N
10
10
10
Robust mean Algo A
3.97
2.20
14.4
Robust STDev
0.168
0.0768
0.392
Median
3.98
2.20
14.4
STDev from MAD
0.174
0.0701
0.371
Arithmetic mean
3.96
2.18
14.4
STDev
0.162
0.108
0.345
CV or Variability
4.2%
3.5%
2.7%
PC-U-R1401
PC-U-R1402
PC-U-R1403
ICP-MS (collision/reaction cell)
N
7
7
7
Robust mean Algo A
3.96
2.15
14.7
Robust STDev
0.333
0.122
0.457
Median
3.98
2.16
14.7
STDev from MAD
0.282
0.133
0.438
Arithmetic mean
3.98
2.15
14.6
STDev
0.345
0.108
0.588
CV or Variability
8.4%
5.7%
3.1%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
34
Distribution
Urine Copper (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
35
Individual results
Urine Fluoride (µmol/L)
Round #2014-01
Participant
PC-U-F1401
z’-score
PC-U-F1402
z’-score
PC-U-F1403
z’-score
Method
176
26.9
-0.23
57.4
0.01
253
-0.18
FSE
1095
28.0
0.09
58.0
0.14
259
0.19
FSE
1418
28.4
0.21
57.4
0.01
257
0.06
ND
1476
26.0
-0.49
58.0
0.14
258
0.13
FSE
2629
27.1
-0.18
54.1
-0.64
226
-1.95
FSE
4604
30.4
0.77
57.1
-0.04
244
-0.76
ND
5132
28.1
0.10
57.3
-0.01
249
-0.45
ND
5881
27.4
-0.09
58.4
0.22
274
1.19
FSE
6200
27.4
-0.09
56.3
-0.19
243
-0.83
FSE
6234
26.4
-0.37
55.3
-0.40
254
-0.16
ND
6545
30.6
0.83
59.5
0.44
261
0.31
FSE
6702
29.4
0.49
60.1
0.56
270
0.90
FSE
7269
28.0
0.09
60.0
0.54
259
0.19
FSE
8701
15.4
-3.53
13.2
-8.75
16.3
-15.49
ND
9759
5.26
-6.42
10.0
-9.39
44.7
-13.65
FSE
9908
30.3
0.75
60.5
0.64
263
0.46
FSE
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-U-F1401
27.7
0.550
3.45
20.7 - 34.7
Rejected
---
PC-U-F1402
57.3
0.773
4.98
47.2 - 67.4
Rejected
---
PC-U-F1403
256
2.89
15.2
225 - 287
Accepted
---
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
36
Statistics
Urine Fluoride (µmol/L)
All methods
PC-U-F1401
PC-U-F1402
16
16
14
Robust mean Algo A
27.7
57.3
256
Robust STDev
1.76
2.47
8.65
Median
27.7
57.4
257
STDev from MAD
1.54
2.32
7.42
Arithmetic mean
25.9
52.0
255
STDev
6.52
15.9
12.1
CV or Variability
6.3%
4.3%
3.4%
PC-U-F1401
PC-U-F1402
PC-U-F1403
11
11
10
Robust mean Algo A
27.5
57.9
259
Robust STDev
1.16
2.49
8.85
Median
27.4
58.0
259
STDev from MAD
0.933
2.49
7.42
Arithmetic mean
26.0
53.8
257
STDev
7.04
14.7
13.8
CV or Variability
4.2%
4.3%
3.4%
N
Fluoride specific electrode
N
PC-U-F1403
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
37
Distribution
Urine Fluoride (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
38
Individual results
Urine Inorganic arsenic (µmol/L)
Round #2014-01
Participant
PC-U-S1401
z’-score
PC-U-S1402
z’-score
PC-U-S1403
z’-score
Method
217
0.540
1.25
1.31
-0.86
0.620
-0.44
GFAAS
317
0.427
-0.63
1.35
-0.60
0.668
0.18
GFAAS
428
0.483
0.30
1.36
-0.52
0.625
-0.38
ICP-MS (C/R)
747
0.451
-0.23
1.48
0.26
0.692
0.50
ICP-MS (C/R)
1095
0.450
-0.25
1.44
0.00
0.660
0.08
GFAAS
1418
0.426
-0.65
1.47
0.19
0.780
1.64
HG-AAS
1476
0.410
-0.92
1.01
-2.85
0.520
-1.75
ICP-MS
1820
0.474
0.15
1.39
-0.33
0.679
0.33
GFAAS
1827
0.536
1.18
1.55
0.73
0.670
0.21
ICP-MS (C/R)
1865
0.416
-0.81
1.57
0.86
0.727
0.96
HG-AAS
2580
0.398
-1.12
1.45
0.07
0.716
0.81
GFAAS
2978
0.490
0.41
1.47
0.19
0.654
0.00
ICP-MS
3215
0.450
-0.25
1.48
0.26
0.670
0.21
GFAAS
3423
0.414
-0.85
1.28
-1.05
0.601
-0.70
HG-AAS
3853
0.505
0.67
1.49
0.33
0.650
-0.05
ICP-MS (C/R)
4953
0.522
0.95
1.95
3.37
0.715
0.80
ICP-MS (C/R)
5375
0.491
0.43
1.47
0.20
0.671
0.22
ICP-MS
5495
0.574
1.81
1.43
-0.10
0.576
-1.01
ICP-MS (C/R)
5691
0.450
-0.25
1.38
-0.40
0.590
-0.83
ND
5881
0.379
-1.43
1.19
-1.63
0.626
-0.37
HG-AAS
6511
0.529
1.06
1.53
0.63
0.622
-0.42
ND
7162
0.414
-0.85
1.44
-0.01
0.641
-0.17
ND
8701
0.502
0.62
1.45
0.09
0.647
-0.09
ND
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
0.465
0.0146
0.0581
0.345 - 0.585
Accepted
DMAA added
PC-U-S1402
1.44
0.0242
0.149
1.14 - 1.74
Rejected
Workers Profile
PC-U-S1403
0.654
0.0124
0.0757
0.501 - 0.807
Accepted
As+3 added
PC-U-S1401
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
39
Statistics
Urine Inorganic arsenic (µmol/L)
All methods
PC-U-S1401
PC-U-S1402
23
23
23
Robust mean Algo A
0.465
1.44
0.654
Robust STDev
0.0559
0.0928
0.0476
Median
0.451
1.45
0.654
STDev from MAD
0.0576
0.0905
0.0435
N
PC-U-S1403
Arithmetic mean
0.467
1.43
0.653
STDev
0.0525
0.167
0.0551
CV or Variability
12.0%
6.5%
7.3%
PC-U-S1401
PC-U-S1402
PC-U-S1403
6
6
6
Robust mean Algo A
0.450
1.40
0.669
Robust STDev
0.0410
0.0739
0.0166
Median
0.450
1.42
0.669
STDev from MAD
0.0349
0.0749
0.0141
Graphite furnace-AAS
N
Arithmetic mean
0.457
1.40
0.669
STDev
0.0483
0.0652
0.0310
9.1%
5.3%
2.5%
PC-U-S1401
PC-U-S1402
PC-U-S1403
CV or Variability
Hydride generation-AAS
N
4
4
4
Robust mean Algo A
0.414
1.38
0.683
Robust STDev
0.0115
0.194
0.0958
Median
0.415
1.37
0.677
STDev from MAD
0.00911
0.203
0.0940
Arithmetic mean
0.409
1.38
0.683
STDev
0.0205
0.171
0.0845
2.8%
14.1%
14.0%
PC-U-S1401
PC-U-S1402
PC-U-S1403
CV or Variability
ICP-MS
N
Robust mean Algo A
Robust STDev
Median
3
3
3
0.489
1.47
0.647
0.00216
0.00337
0.0318
0.490
1.47
0.654
STDev from MAD
0.00171
0.00267
0.0252
Arithmetic mean
0.464
1.32
0.615
STDev
0.0464
0.265
0.0827
0.4%
0.2%
4.9%
PC-U-S1401
PC-U-S1402
PC-U-S1403
6
6
6
CV or Variability
ICP-MS (collision/reaction cell)
N
Robust mean Algo A
0.512
1.49
0.656
Robust STDev
0.0467
0.104
0.0534
Median
0.513
1.49
0.660
STDev from MAD
0.0392
0.0924
0.0499
Arithmetic mean
0.512
1.54
0.655
STDev
0.0426
0.209
0.0497
9.1%
7.0%
8.1%
CV or Variability
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
40
Distribution
Urine Inorganic arsenic (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
41
Individual results
Urine Iodide (µmol/L)
Round #2014-01
Participant
PC-U-I1401
z’-score
PC-U-I1402
z’-score
PC-U-I1403
z’-score
217
0.650
0.68
1.71
0.06
2.20
0.09
Method
ICP-MS
428
0.545
-1.03
1.57
-0.76
2.01
-0.77
ICP-MS (C/R)
747
0.595
-0.21
1.69
-0.06
2.17
-0.05
ICP-MS
1095
0.620
0.19
1.78
0.46
2.32
0.63
ICP-MS (C/R)
1855
0.599
-0.15
1.69
-0.03
2.30
0.55
ICP-MS
2763
0.667
0.96
1.84
0.81
2.28
0.45
ICP-MS
3187
0.597
-0.18
1.59
-0.64
2.13
-0.23
ICP-MS
3513
0.600
-0.13
1.70
0.00
2.15
-0.14
ICP-MS
4708
0.607
-0.02
1.71
0.06
2.20
0.09
ICP-MS
5881
0.655
0.76
1.76
0.37
2.24
0.29
ICP-MS (C/R)
6200
0.655
0.76
1.87
0.97
2.29
0.51
ICP-MS
6511
0.587
-0.34
1.66
-0.23
2.07
-0.50
ND
6545
0.610
0.03
1.69
-0.06
2.15
-0.14
ICP-MS
8981
0.550
-0.94
1.47
-1.33
1.92
-1.17
ND
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-U-I1401
0.608
0.00971
0.0608
0.485 - 0.731
Accepted
---
PC-U-I1402
1.70
0.0295
0.170
1.36 - 2.04
Accepted
---
PC-U-I1403
2.18
0.0384
0.218
1.74 - 2.62
Accepted
---
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
42
Statistics
Urine Iodide (µmol/L)
All methods
PC-U-I1401
PC-U-I1402
14
14
14
Robust mean Algo A
0.608
1.70
2.18
Robust STDev
0.0291
0.0884
0.115
Median
0.604
1.70
2.19
STDev from MAD
0.0244
0.0777
0.114
N
PC-U-I1403
Arithmetic mean
0.610
1.70
2.17
STDev
0.0372
0.105
0.116
4.8%
5.2%
5.3%
PC-U-I1401
PC-U-I1402
PC-U-I1403
9
9
9
Robust mean Algo A
0.611
1.70
2.21
Robust STDev
0.0167
0.0174
0.0756
Median
0.607
1.70
2.20
STDev from MAD
0.0148
0.0148
0.0742
CV or Variability
ICP-MS
N
Arithmetic mean
0.620
1.72
2.21
STDev
0.0287
0.0836
0.0667
2.7%
1.0%
3.4%
PC-U-I1401
PC-U-I1402
PC-U-I1403
CV or Variability
ICP-MS (collision/reaction cell)
N
3
3
3
Robust mean Algo A
0.606
1.76
2.21
Robust STDev
0.0640
0.0294
0.143
Median
0.620
1.76
2.24
STDev from MAD
0.0516
0.0233
0.114
Arithmetic mean
0.606
1.70
2.19
STDev
0.0564
0.118
0.162
CV or Variability
10.5%
1.7%
6.5%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
43
Distribution
Urine Iodide (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
44
Individual results
Urine Lead (µmol/L)
Round #2014-01
Participant
PC-U-P1401
z’-score
PC-U-P1402
z’-score
PC-U-P1403
z’-score
Method
176
0.0483
-1.55
0.767
-0.12
0.420
0.36
ICP-MS
194
0.0630
0.98
0.777
0.03
0.428
0.60
ND
217
0.0700
2.18
0.860
1.37
0.430
0.66
ICP-MS
744
0.0864
4.99
0.760
-0.24
0.395
-0.37
ND
747
0.0563
-0.17
0.783
0.13
0.405
-0.09
ICP-MS
1095
0.0600
0.46
0.860
1.37
0.450
1.26
ICP-MS (C/R)
1109
0.0538
-0.60
0.749
-0.42
0.386
-0.67
ND
1855
0.0579
0.11
0.734
-0.67
0.376
-0.94
ICP-MS
2182
0.111
9.30
0.927
2.44
0.516
3.24
GFAAS
3167
0.0400
-2.97
0.780
0.08
0.420
0.36
GFAAS
3187
0.0587
0.24
0.804
0.47
0.428
0.60
ICP-MS
3211
0.0540
-0.57
0.780
0.08
0.411
0.09
GFAAS
3423
0.0700
2.18
0.796
0.34
0.421
0.40
GFAAS
3853
0.0570
-0.05
0.769
-0.10
0.393
-0.45
ICP-MS
3970
0.0531
-0.72
0.820
0.73
0.401
-0.22
GFAAS
4090
0.837
133.88
0.420
-5.71
0.0530
-10.61
ICP-MS (C/R)
4708
0.0580
0.12
0.791
0.26
0.430
0.66
ICP-MS
4953
0.0550
-0.39
0.806
0.50
0.416
0.23
ICP-MS
5591
0.0500
-1.25
0.730
-0.72
0.390
-0.54
ICP-MS
5654
0.0509
-1.10
0.726
-0.78
0.369
-1.18
ICP-MS (C/R)
5691
0.0600
0.46
0.770
-0.08
0.400
-0.24
ICP-MS
5881
0.0533
-0.69
0.754
-0.34
0.389
-0.58
ICP-MS (C/R)
6511
0.0560
-0.23
0.787
0.19
0.411
0.10
ND
6545
0.0600
0.46
0.760
-0.24
0.410
0.06
ICP-MS
7111
0.0570
-0.05
0.811
0.58
0.407
-0.03
ICP-MS
7804
0.0307
-4.57
0.408
-5.90
0.310
-2.92
ND
9674
0.0864
4.99
0.426
-5.62
0.763
10.60
GFAAS
9759
0.0994
7.23
>LL
---
>LL
---
GFAAS
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-U-P1401
0.0573
0.00154
0.00561
0.0457 - 0.0689
Rejected
---
PC-U-P1402
0.775
0.0101
0.0613
0.651 - 0.899
Rejected
---
PC-U-P1403
0.408
0.00638
0.0329
0.341 - 0.475
Rejected
---
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
45
Statistics
Urine Lead (µmol/L)
All methods
PC-U-P1401
PC-U-P1402
28
27
27
Robust mean Algo A
0.0573
0.775
0.408
Robust STDev
0.00652
0.0420
0.0265
Median
0.0570
0.777
0.410
STDev from MAD
0.00566
0.0400
0.0267
Arithmetic mean
0.0610
0.746
0.408
STDev
0.0169
0.126
0.104
CV or Variability
11.4%
5.4%
6.5%
PC-U-P1401
PC-U-P1402
PC-U-P1403
7
6
6
Robust mean Algo A
0.0729
0.792
0.427
Robust STDev
0.0290
0.0366
0.0252
Median
0.0700
0.788
0.421
STDev from MAD
0.0251
0.0300
0.0221
Arithmetic mean
0.0735
0.755
0.489
STDev
0.0265
0.170
0.141
CV or Variability
39.8%
4.6%
5.9%
PC-U-P1401
PC-U-P1402
PC-U-P1403
N
Graphite furnace-AAS
N
ICP-MS
N
PC-U-P1403
12
12
12
Robust mean Algo A
0.0574
0.779
0.409
Robust STDev
0.00292
0.0339
0.0185
Median
0.0575
0.777
0.409
STDev from MAD
0.00273
0.0326
0.0199
Arithmetic mean
0.0573
0.782
0.409
STDev
0.00539
0.0358
0.0170
5.1%
4.4%
4.5%
PC-U-P1401
PC-U-P1402
PC-U-P1403
CV or Variability
ICP-MS (collision/reaction cell)
N
4
4
4
Robust mean Algo A
0.0524
0.733
0.374
Robust STDev
0.00217
0.125
0.0758
Median
0.0521
0.740
0.379
STDev from MAD
0.00179
0.0990
0.0603
Arithmetic mean
0.0538
0.690
0.315
STDev
0.00432
0.189
0.178
4.1%
17.1%
20.3%
CV or Variability
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
46
Distribution
Urine Lead (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
47
Individual results
Urine Mercury (nmol/L)
Round #2014-01
Participant
PC-U-H1401
z’-score
PC-U-H1402
z’-score
PC-U-H1403
z’-score
Method
176
84.8
0.02
115
0.04
533
0.09
ICP-MS
217
80.0
-0.34
109
-0.30
514
-0.22
ICP-MS
428
97.2
0.95
111
-0.20
553
0.40
ICP-MS (C/R)
720
59.8
-1.84
94.7
-1.15
528
0.01
CV
744
93.0
0.63
133
1.13
609
1.28
ND
1095
90.0
0.41
123
0.54
638
1.74
CV
1109
22.8
-4.60
13.7
-6.00
407
-1.92
ND
1156
82.3
-0.16
97.0
-1.02
550
0.36
ND
1418
79.7
-0.36
108
-0.35
485
-0.68
ND
1865
90.7
0.47
126
0.73
533
0.09
CV
2629
60.3
-1.80
83.3
-1.84
265
-4.15
ICP-MS (C/R)
2982
82.8
-0.13
119
0.28
577
0.78
CV
3468
86.5
0.15
115
0.03
540
0.19
GA-AAS
3513
87.0
0.19
120
0.36
593
1.03
ICP-MS
3853
89.0
0.34
122
0.48
542
0.22
ICP-MS
4708
87.7
0.24
122
0.48
559
0.49
ICP-MS
4953
94.2
0.73
129
0.87
568
0.64
ICP-MS
5029
9.03
-5.63
24.4
-5.36
144
-6.07
ND
5491
80.0
-0.34
104
-0.60
532
0.06
CV
5591
82.8
-0.13
115
0.07
557
0.45
ICP-MS
5654
92.7
0.61
111
-0.21
460
-1.08
ICP-MS (C/R)
5691
48.0
-2.72
52.0
-3.71
205
-5.10
ICP-MS
5881
62.8
-1.62
110
-0.26
494
-0.54
ICP-MS (C/R)
5980
14.9
-5.19
20.8
-5.58
95.6
-6.83
ND
6200
87.5
0.22
113
-0.04
533
0.07
ICP-MS
6210
83.3
-0.09
117
0.16
536
0.13
ND
6511
69.3
-1.13
83.3
-1.84
263
-4.19
ND
6545
85.9
0.10
119
0.28
564
0.57
ICP-MS
6702
83.3
-0.09
112
-0.12
505
-0.36
CV
6794
87.7
0.24
123
0.52
600
1.13
GA-AAS
6892
83.6
-0.07
117
0.18
538
0.16
ND
6920
79.3
-0.39
106
-0.51
421
-1.69
ND
7184
98.3
1.03
135
1.24
597
1.09
CV
7190
78.8
-0.43
108
-0.38
467
-0.96
ND
7269
84.0
-0.04
119
0.30
540
0.19
CV
7804
132
3.55
122
0.48
177
-5.55
ND
7864
98.0
1.01
123
0.54
541
0.21
ND
8701
85.6
0.08
123
0.53
531
0.05
ND
9674
90.7
0.47
124
0.61
568
0.64
CV
9759
111
1.99
152
2.25
649
1.91
GA-AAS
9777
86.1
0.12
114
0.02
516
-0.18
GA-AAS
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-U-H1401
84.5
1.68
13.3
57.7 - 111
Rejected
---
PC-U-H1402
114
2.28
16.6
80.6 - 147
Rejected
---
PC-U-H1403
528
11.0
62.3
401 - 655
Rejected
---
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
48
Statistics
Urine Mercury (nmol/L)
All methods
PC-U-H1401
PC-U-H1402
41
41
41
Robust mean Algo A
84.5
114
528
Robust STDev
8.60
11.7
56.5
Median
84.8
115
533
STDev from MAD
7.79
10.9
51.8
Arithmetic mean
80.1
107
489
STDev
22.8
29.5
136
CV or Variability
10.2%
10.2%
10.7%
PC-U-H1401
PC-U-H1402
PC-U-H1403
9
9
9
Robust mean Algo A
85.7
118
554
Robust STDev
8.35
11.7
38.4
Median
84.0
119
540
STDev from MAD
8.90
10.4
42.0
Arithmetic mean
84.4
117
558
STDev
10.8
12.2
41.4
CV or Variability
9.7%
9.9%
6.9%
PC-U-H1401
PC-U-H1402
PC-U-H1403
N
Cold vapor
N
Gold amalgamation-AAS
N
PC-U-H1403
4
4
4
Robust mean Algo A
87.3
120
576
Robust STDev
1.44
7.53
67.7
Median
87.1
119
570
STDev from MAD
1.20
6.21
61.9
Arithmetic mean
92.9
126
576
STDev
12.2
17.6
59.7
CV or Variability
1.6%
6.3%
11.7%
PC-U-H1401
PC-U-H1402
PC-U-H1403
ICP-MS
N
10
10
10
Robust mean Algo A
85.9
117
547
Robust STDev
3.59
6.92
27.0
Median
86.5
117
549
STDev from MAD
3.15
6.44
24.1
Arithmetic mean
82.7
112
517
STDev
12.8
21.6
112
CV or Variability
4.2%
5.9%
4.9%
PC-U-H1401
PC-U-H1402
PC-U-H1403
4
4
4
ICP-MS (collision/reaction cell)
N
Robust mean Algo A
78.3
110
470
Robust STDev
22.0
0.890
85.8
Median
77.7
110
477
STDev from MAD
24.0
0.739
69.6
Arithmetic mean
78.3
104
443
STDev
19.4
13.5
125
CV or Variability
28.1%
0.8%
18.3%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
49
Distribution
Urine Mercury (nmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
50
Individual results
Urine Selenium (µmol/L)
Round #2014-01
Participant
PC-U-N1401
z’-score
PC-U-N1402
z’-score
PC-U-N1403
z’-score
Method
747
0.966
-0.19
2.24
-0.09
1.90
-0.20
ICP-MS
3187
1.06
0.22
2.39
0.35
2.01
0.16
ICP-MS
3423
1.03
0.07
1.79
-1.42
1.96
0.01
HG-AAS
3853
1.06
0.22
2.44
0.50
2.10
0.46
ICP-MS (C/R)
4090
0.980
-0.13
2.25
-0.06
1.93
-0.10
ICP-MS (C/R)
5691
0.910
-0.44
2.12
-0.44
1.82
-0.46
ICP-MS
5881
0.950
-0.26
2.23
-0.11
1.89
-0.23
ICP-MS (C/R)
6511
1.39
1.65
2.81
1.57
2.35
1.29
ND
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-U-N1401
1.01
0.0354
0.224
0.556 - 1.46
Rejected
Spiked with TMSe
PC-U-N1402
2.27
0.0943
0.328
1.59 - 2.95
Accepted
Workers Profile
PC-U-N1403
1.96
0.0463
0.303
1.35 - 2.57
Accepted
Selenomethionine added
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
51
Statistics
Urine Selenium (µmol/L)
All methods
PC-U-N1401
PC-U-N1402
8
8
8
1.01
2.27
1.96
0.0801
0.213
0.105
1.00
2.25
1.95
0.0814
0.200
0.0884
N
Robust mean Algo A
Robust STDev
Median
STDev from MAD
PC-U-N1403
Arithmetic mean
1.04
2.28
2.00
STDev
0.149
0.291
0.167
CV or Variability
7.9%
9.4%
5.3%
PC-U-N1401
PC-U-N1402
PC-U-N1403
3
3
3
Robust mean Algo A
0.979
2.25
1.91
Robust STDev
0.0860
0.153
0.108
Median
0.966
2.24
1.90
STDev from MAD
0.0830
0.178
0.119
ICP-MS
N
Arithmetic mean
0.979
2.25
1.91
STDev
0.0758
0.135
0.0954
8.8%
6.8%
5.7%
PC-U-N1401
PC-U-N1402
PC-U-N1403
CV or Variability
ICP-MS (collision/reaction cell)
N
3
3
3
Robust mean Algo A
0.992
2.26
1.95
Robust STDev
0.0557
0.0346
0.0733
Median
0.980
2.25
1.93
STDev from MAD
0.0442
0.0274
0.0581
Arithmetic mean
0.997
2.31
1.97
STDev
0.0568
0.115
0.111
5.6%
1.5%
3.8%
CV or Variability
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
52
Distribution
Urine Selenium (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
53
Individual results
Urine Total arsenic (µmol/L)
Round #2014-01
Participant
PC-U-S1401
z’-score
PC-U-S1402
z’-score
PC-U-S1403
z’-score
Method
176
0.641
1.07
2.00
0.64
0.787
0.92
ICP-MS
744
0.231
-5.91
0.921
-6.17
0.474
-3.61
ND
ICP-MS
747
0.567
-0.19
1.77
-0.82
0.707
-0.25
1109
0.706
2.18
2.04
0.87
0.793
0.99
ND
1476
0.560
-0.31
1.94
0.25
0.720
-0.06
ICP-MS
1827
0.577
-0.02
1.79
-0.69
0.682
-0.61
ICP-MS (C/R)
1865
0.579
0.02
2.02
0.74
0.727
0.05
ICP-MS (C/R)
2182
0.464
-1.93
1.82
-0.53
0.685
-0.57
GFAAS
2937
0.653
1.28
1.81
-0.57
0.784
0.87
ICP-MS
2978
0.490
-1.50
1.76
-0.87
0.654
-1.01
ICP-MS
3187
0.558
-0.34
1.86
-0.25
0.703
-0.30
ICP-MS
3423
0.534
-0.75
1.92
0.14
0.734
0.15
HG-AAS
3513
0.610
0.55
2.15
1.58
0.870
2.11
ICP-MS
3853
0.634
0.95
2.13
1.44
0.787
0.91
ICP-MS (C/R)
4708
0.567
-0.19
1.93
0.19
0.740
0.23
ICP-MS
5375
0.532
-0.78
1.85
-0.32
0.733
0.13
ICP-MS
5495
0.634
0.95
1.73
-1.10
0.628
-1.38
ICP-MS (C/R)
5591
0.558
-0.34
1.92
0.10
0.726
0.03
ICP-MS
5654
0.688
1.88
1.92
0.10
0.782
0.83
ICP-MS (C/R)
5691
0.530
-0.82
1.77
-0.82
0.680
-0.63
ND
5881
0.590
0.21
1.97
0.42
0.760
0.52
ICP-MS (C/R)
6511
0.571
-0.11
1.90
0.00
0.745
0.30
ND
6892
0.718
2.39
2.09
1.20
0.820
1.38
ND
7864
0.614
0.61
2.02
0.76
0.654
-1.01
ND
9674
0.505
-1.25
1.79
-0.70
0.626
-1.41
GFAAS
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
PC-U-S1401
0.578
0.0164
0.0564
0.461 - 0.695
Accepted
DMAA added
PC-U-S1402
1.90
0.0347
0.155
1.58 - 2.22
Accepted
Workers Profile
PC-U-S1403
0.724
0.0170
0.0672
0.585 - 0.863
Accepted
As+3 added
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
Species
54
Statistics
Urine Total arsenic (µmol/L)
All methods
PC-U-S1401
PC-U-S1402
25
25
25
Robust mean Algo A
0.578
1.90
0.724
Robust STDev
0.0656
0.139
0.0681
Median
0.571
1.92
0.727
STDev from MAD
0.0612
0.155
0.0703
N
PC-U-S1403
Arithmetic mean
0.572
1.87
0.720
STDev
0.0956
0.231
0.0789
CV or Variability
11.3%
7.3%
9.4%
PC-U-S1401
PC-U-S1402
PC-U-S1403
10
10
10
Robust mean Algo A
0.568
1.89
0.736
Robust STDev
0.0331
0.105
0.0430
Median
0.564
1.89
0.730
STDev from MAD
0.0274
0.0971
0.0363
ICP-MS
N
Arithmetic mean
0.574
1.90
0.742
STDev
0.0490
0.117
0.0592
5.8%
5.6%
5.8%
PC-U-S1401
PC-U-S1402
PC-U-S1403
CV or Variability
ICP-MS (collision/reaction cell)
N
6
6
6
Robust mean Algo A
0.615
1.92
0.732
Robust STDev
0.0436
0.168
0.0620
Median
0.612
1.94
0.744
STDev from MAD
0.0406
0.168
0.0602
Arithmetic mean
0.617
1.92
0.728
STDev
0.0432
0.148
0.0624
7.1%
8.7%
8.5%
CV or Variability
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
55
Distribution
Urine Total arsenic (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
56
Individual results
Urine Zinc (µmol/L)
Round #2014-01
Participant
PC-U-R1401
z’-score
PC-U-R1402
z’-score
PC-U-R1403
z’-score
Method
176
11.0
0.20
8.44
0.00
14.7
0.07
ICP-MS
747
11.2
0.42
8.32
-0.16
14.8
0.16
ICP-MS
1095
10.3
-0.51
7.83
-0.82
13.6
-0.79
FAAS
1109
12.6
1.86
10.3
2.57
16.3
1.34
ND
1188
14.3
3.64
10.3
2.51
15.4
0.59
ICP-MS (C/R)
1418
9.78
-1.06
7.85
-0.79
14.0
-0.51
ICP-MS (C/R)
2629
9.10
-1.77
7.12
-1.78
12.4
-1.72
ICP-OES
2763
10.4
-0.42
8.29
-0.20
14.2
-0.31
ICP-MS (C/R)
3187
10.2
-0.62
8.11
-0.44
15.0
0.31
ICP-MS
3211
11.0
0.21
9.00
0.75
14.8
0.16
FAAS
3423
13.1
2.36
8.79
0.47
16.4
1.41
FAAS
3513
11.5
0.73
8.90
0.62
15.2
0.47
ICP-MS
3853
9.65
-1.19
7.60
-1.13
12.8
-1.46
ICP-MS
4090
10.5
-0.30
8.10
-0.46
14.4
-0.14
ICP-MS (C/R)
4708
10.7
-0.10
8.55
0.15
14.3
-0.24
ICP-MS
4953
10.6
-0.18
8.30
-0.19
14.2
-0.29
ICP-MS
5591
11.0
0.21
8.40
-0.05
14.1
-0.39
FAAS
5691
10.0
-0.83
7.90
-0.73
13.5
-0.87
ICP-MS
5881
10.7
-0.14
8.18
-0.35
14.2
-0.34
ICP-MS (C/R)
6511
11.7
0.96
9.42
1.32
15.3
0.59
ND
7804
7.61
-3.32
8.25
-0.26
15.8
0.98
ND
8376
11.6
0.79
8.67
0.32
14.6
-0.01
FAAS
8454
8.51
-2.38
6.59
-2.49
12.2
-1.89
FAAS
8981
11.0
0.21
10.1
2.24
16.2
1.26
ND
9759
19.8
9.34
9.65
1.63
14.6
0.03
FAAS
Assigned value
Standard
uncertainty
σ pt
Acceptable range
PC-U-R1401
10.8
0.277
0.919
PC-U-R1402
8.44
0.177
0.721
PC-U-R1403
14.6
0.244
1.24
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
K-S (Lilliefors)
Species
8.88 - 12.7
Rejected
---
6.96 - 9.92
Accepted
---
12.1 - 17.1
Accepted
---
57
Statistics
Urine Zinc (µmol/L)
All methods
PC-U-R1401
PC-U-R1402
25
25
25
Robust mean Algo A
10.8
8.44
14.6
Robust STDev
1.11
0.707
0.975
Median
10.7
8.32
14.6
STDev from MAD
1.04
0.696
0.903
Arithmetic mean
11.1
8.52
14.5
STDev
2.27
0.915
1.10
CV or Variability
10.3%
8.4%
6.7%
PC-U-R1401
PC-U-R1402
PC-U-R1403
7
7
7
Robust mean Algo A
11.2
8.60
14.4
Robust STDev
1.27
0.607
0.859
Median
11.0
8.67
14.6
STDev from MAD
1.02
0.482
0.729
Arithmetic mean
12.2
8.42
14.3
STDev
3.62
0.979
1.27
CV or Variability
11.4%
7.1%
6.0%
PC-U-R1401
PC-U-R1402
PC-U-R1403
N
Flame-AAS
N
ICP-MS
N
PC-U-R1403
8
8
8
Robust mean Algo A
10.6
8.28
14.4
Robust STDev
0.712
0.372
0.686
Median
10.7
8.31
14.5
STDev from MAD
0.742
0.326
0.599
Arithmetic mean
10.6
8.27
14.3
STDev
0.628
0.400
0.824
CV or Variability
6.7%
4.5%
4.8%
PC-U-R1401
PC-U-R1402
PC-U-R1403
ICP-MS (collision/reaction cell)
N
5
5
5
Robust mean Algo A
10.5
8.19
14.3
Robust STDev
0.305
0.207
0.315
Median
10.5
8.18
14.2
STDev from MAD
0.237
0.160
0.326
Arithmetic mean
11.1
8.54
14.4
STDev
1.80
0.995
0.545
CV or Variability
2.9%
2.5%
2.2%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
58
Distribution
Urine Zinc (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
59
Interlaboratory Comparison Program
for Metals in Biological Matrices
ASSIGNED VALUES
ROUND:
2014-01
SHIPPED ON: 2014-01-20
DEADLINE: 2014-02-28
UNIT
PTM
ASSIGNED
VALUE
PTM
ASSIGNED
VALUE
PTM
ASSIGNED
VALUE
Cadmium
nmol/L
PC-B-C1401
8.88
PC-B-C1402
104
PC-B-C1403
23.2
Lead
µmol/L
PC-B-L1401
1.32
PC-B-L1402
0.295
PC-B-L1403
3.87
Mercury
nmol/L
PC-B-M1401
20.8
PC-B-M1402
9.09
PC-B-M1403
363
Aluminium
µmol/L
PC-S-A1401
1.46
PC-S-A1402
0.643
PC-S-A1403
6.27
Copper
µmol/L
PC-S-E1401
16.7
PC-S-E1402
27.1
PC-S-E1403
9.67
Manganese
nmol/L
PC-S-G1401
29.9
PC-S-G1402
11.5
PC-S-G1403
53.6
Selenium
µmol/L
PC-S-E1401
1.68
PC-S-E1402
2.20
PC-S-E1403
1.34
Zinc
µmol/L
PC-S-E1401
19.0
PC-S-E1402
26.9
PC-S-E1403
12.4
Cadmium
nmol/L
PC-U-D1401
93.1
PC-U-D1402
19.3
PC-U-D1403
52.9
Chromium
nmol/L
PC-U-B1401
22.1
PC-U-B1402
240
PC-U-B1403
34.2
Copper
µmol/L
PC-U-R1401
4.01
PC-U-R1402
2.14
PC-U-R1403
14.6
Fluoride
µmol/L
PC-U-F1401
27.7
PC-U-F1402
57.3
PC-U-F1403
256
Inorganic arsenic
µmol/L
PC-U-S1401
0.465
PC-U-S1402
1.44
PC-U-S1403
0.654
Iodide
µmol/L
PC-U-I1401
0.608
PC-U-I1402
1.70
PC-U-I1403
2.18
Lead
µmol/L
PC-U-P1401
0.0573
PC-U-P1402
0.775
PC-U-P1403
0.408
Mercury
nmol/L
PC-U-H1401
84.5
PC-U-H1402
114
PC-U-H1403
528
Selenium
µmol/L
PC-U-N1401
1.01
PC-U-N1402
2.27
PC-U-N1403
1.96
Total arsenic
µmol/L
PC-U-S1401
0.578
PC-U-S1402
1.90
PC-U-S1403
0.724
Zinc
µmol/L
PC-U-R1401
10.8
PC-U-R1402
8.44
PC-U-R1403
14.6
MATRIX
Blood
Serum
Urine
ANALYTE
Centre de toxicologie/INSPQ
945, Ave Wolfe
Quebec, QC
Canada, G1V 5B3
Phone: (418) 650-5115 Ext. 5254
Fax : (418) 654-2148
E-mail : [email protected]
http://www.inspq.qc.a/ctq
60
Interlaboratory Comparison Program for Metals in
Biological Matrices (PCI)
GROUPING OF ANALYTICAL METHODS
FOR STATISTICS
METHODS GROUPING
CODE
METHODS GROUPING
METHODS INCLUDED
METHODS CODE
Atomic fluorescence
AFS
AFS
Atomic fluorescence
Cold vapor-atomic
fluorescence
CV-AFS
COLOR
Colorimetry
Colorimetry
Color
CV
Cold vapor
Cold vapor
CV
Cold vapor-AAS
CV-AAS
ESA
ESA Lead Care TM
system
ESA Lead Care TM
system
ESA Lead
FAAS
Flame-AAS
Flame-AAS
FAAS
FSE
Fluoride specific
electrode
Fluoride specific
electrode
FSE
GA-AAS
Gold amalgamationAAS
Gold amalgamationAAS
AA-Gold A
Deuterium and otherGraphite furnace-AAS
D2-GFAAS
Zeeman-Graphite
furnace-AAS
Z-GFAAS
GFAAS
Graphite furnace-AAS
HG-AAS
Hydride generationAAS
Hydride generationAAS
HG-AAS
HR-ICP-MS
ICP-MS (high
resolution)
ICP-MS (high
resolution)
HR-ICP-MS
ICP-MS
ICP-MS
ICP-MS (isotopic
dilution)
ID-ICP-MS
ICP-MS (laser
ablation/furnace)
ICP-MS (LA)
ICP-MS
ICP-MS
ICP-MS (C/R)
ICP-MS
(collision/reaction
cell)
ICP-MS
(collision/reaction
cell)
ICP-MS(C/R)
ICP-OES
ICP-OES (optical
emission)
ICP-OES (optical
emission)
ICP-OES
POL
Polarography
Polarography
Polaro
Centre de toxicologie/INSPQ
945, Ave Wolfe
Quebec, QC
Canada, G1V 5B3
Phone: (418) 650-5115 Ext. 5254
Fax : (418) 654-2148
E-mail : [email protected]
http://www.inspq.qc.a/ctq
61
| File Type | application/pdf |
| Author | David Bisson |
| File Modified | 2014-03-18 |
| File Created | 2014-03-18 |