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pdfINTERLABORATORY COMPARISON PROGRAM
FOR METALS IN BIOLOGICAL MATRICES
(PCI)
REPORT FOR ROUND:
2014-03
PTMS SHIPPING DATE:
2014-04-22
DATE OF PUBLICATION:
2014-06-20
Scope of accreditation: The concentration of arsenic in material PC-U-S1407 exceed the level of
our scope of accreditation.
Centre de toxicologie/INSPQ
945, Ave Wolfe
Quebec, QC
Canada, G1V 5B3
Phone: (418) 650-5115 Ext. 5254
Fax : (418) 654-2148
E-mail : [email protected]
http://www.inspq.qc.a/ctq
Interlaboratory Comparison Program for Metals in
Biological Matrices (PCI)
TABLE OF CONTENTS
INTRODUCTION
1
BLOOD
Cadmium
2
Lead
5
Mercury
9
SERUM
Aluminium
12
Copper
15
Manganese
18
Selenium
21
Zinc
24
URINE
Cadmium
27
Chromium
30
Copper
33
Fluoride
36
Inorganic arsenic
39
Iodide
42
Lead
45
Mercury
48
Selenium
51
Total arsenic
54
Zinc
57
ASSIGNED VALUES
60
GROUPING OF ANALYTICAL METHODS FOR STATISTICS
61
END OF REPORT
62
Centre de toxicologie/INSPQ
945, Ave Wolfe
Quebec, QC
Canada, G1V 5B3
Phone: (418) 650-5115 Ext. 5254
Fax : (418) 654-2148
E-mail : [email protected]
http://www.inspq.qc.a/ctq
Interlaboratory Comparison Program for Metals in
Biological Matrices (PCI)
INTRODUCTION
Dear PCI participants:
This report includes the results and performance evaluations of round 2014-03.
Participating laboratories are identified only by their unique subscription number.
Identity of participants will be kept strictly confidential by the PCI organizer.
For this PT exercise, all analytes meet the homogeneity criteria as per ISO/CEI
17043 and 13528 guidelines with the exception of mercury in material PC-U-H1407.
A note concerning the homogeneity of PC-U-H1407 has been included in the
corresponding section.
A study had been previously performed to demonstrate that all the analytes are
stable for the duration of the PT exercise and meet the stability criteria according
to ISO/CEI 17043 and 13528 guidelines.
Please note that the appendices containing statistical approaches are no longer
included in the reports. You will find them within the “Participant’s Guide”.
We are available to assist you at any time. If you have any questions or concerns
regarding our program, do not hesitate to contact us. Your comments help us
enhance the quality of our schemes.
Best regards,
David Bisson, M.Sc. Chemist
Programs Coordinator
External Quality Assessment Schemes and Reference Materials
Centre de toxicologie du Québec / INSPQ
Tel.: (418) 650-5115, extension 4649
E-mail: [email protected]
Web Site: www.inspq.qc.ca/CTQ/paqe
Centre de toxicologie/INSPQ
945, Ave Wolfe
Quebec, QC
Canada, G1V 5B3
Phone: (418) 650-5115 Ext. 5254
Fax : (418) 654-2148
E-mail : [email protected]
http://www.inspq.qc.a/ctq
1
Individual results
Blood Cadmium (nmol/L)
Round #2014-03
Participant
PC-B-C1407
z’-score
PC-B-C1408
z’-score
PC-B-C1409
z’-score
Method
176
81.8
-0.35
13.3
-0.94
30.2
-0.62
ICP-MS
194
72.6
-1.63
15.1
-0.14
28.2
-1.22
ND
217
79.7
-0.65
17.5
0.96
36.2
1.10
ICP-MS
323
78.0
-0.89
15.0
-0.18
33.0
0.17
GFAAS
747
84.7
0.04
15.1
-0.14
29.9
-0.72
ICP-MS
1095
95.5
1.54
16.6
0.55
34.5
0.61
ICP-MS (C/R)
1109
88.1
0.51
18.7
1.51
35.1
0.79
ND
1188
89.0
0.63
15.0
-0.17
30.8
-0.46
ICP-MS (C/R)
1418
82.6
-0.24
15.2
-0.09
35.1
0.77
ICP-MS (C/R)
1865
85.4
0.14
17.1
0.77
37.1
1.36
ICP-MS (C/R)
2305
92.8
1.17
14.9
-0.22
31.6
-0.22
ND
2991
104
2.76
20.0
2.12
39.3
2.01
ND
3187
83.2
-0.17
15.0
-0.18
30.5
-0.55
ICP-MS
3211
82.3
-0.29
15.7
0.14
32.3
-0.03
GFAAS
3248
70.6
-1.90
12.9
-1.15
27.3
-1.48
GFAAS
3853
88.4
0.55
20.5
2.34
42.9
3.04
ICP-MS
4708
84.1
-0.04
15.3
-0.05
31.1
-0.38
ICP-MS
4953
88.1
0.51
15.1
-0.13
32.9
0.15
ICP-MS
5591
78.9
-0.76
14.8
-0.28
31.3
-0.32
ICP-MS
5654
93.1
1.20
16.7
0.61
35.0
0.74
ICP-MS (C/R)
5691
84.0
-0.06
15.0
-0.18
32.0
-0.12
ICP-MS
6511
82.7
-0.23
15.1
-0.13
32.0
-0.11
ND
6545
81.4
-0.42
---
---
---
---
ICP-MS
6689
84.0
-0.06
16.9
0.69
32.6
0.05
GFAAS
6794
83.7
-0.10
16.5
0.53
30.4
-0.57
GFAAS
6858
84.8
0.06
12.8
-1.20
30.3
-0.60
ICP-MS
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-B-C1407
84.4
1.24
7.11
70.0 - 98.8
Accepted
---
PC-B-C1408
15.4
0.233
2.17
11.0 - 19.8
Rejected1
---
PC-B-C1409
32.4
0.665
3.39
25.5 - 39.3
Accepted
---
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
2
Statistics
Blood Cadmium (nmol/L)
All methods
PC-B-C1407
PC-B-C1408
26
25
25
Robust mean Algo A
84.4
15.4
32.4
Robust STDev
5.07
0.932
2.66
Median
84.0
15.1
32.0
STDev from MAD
4.95
0.856
2.49
Arithmetic mean
84.8
15.8
32.9
STDev
6.87
1.90
3.46
CV or Variability
6.0%
6.0%
8.2%
PC-B-C1407
PC-B-C1408
PC-B-C1409
5
5
5
Robust mean Algo A
81.4
15.6
31.9
Robust STDev
3.04
1.40
1.20
Median
82.3
15.7
32.3
STDev from MAD
2.49
1.26
1.04
Arithmetic mean
79.7
15.4
31.1
STDev
5.62
1.59
2.35
CV or Variability
3.7%
9.0%
3.8%
PC-B-C1407
PC-B-C1408
PC-B-C1409
N
Graphite furnace-AAS
N
ICP-MS
N
PC-B-C1409
11
10
10
Robust mean Algo A
83.6
15.1
31.5
Robust STDev
3.38
0.443
1.45
Median
84.0
15.1
31.2
STDev from MAD
3.20
0.371
1.34
Arithmetic mean
83.6
15.4
32.7
STDev
3.02
2.17
4.02
CV or Variability
4.0%
2.9%
4.6%
PC-B-C1407
PC-B-C1408
PC-B-C1409
ICP-MS (collision/reaction cell)
N
5
5
5
Robust mean Algo A
89.1
16.3
34.9
Robust STDev
6.00
0.814
0.859
Median
89.0
16.6
35.0
STDev from MAD
6.07
0.712
0.684
Arithmetic mean
89.1
16.1
34.5
STDev
5.29
0.939
2.29
CV or Variability
6.7%
5.0%
2.5%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
3
Distribution
Blood Cadmium (nmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
4
Individual results
Blood Lead (µmol/L)
Round #2014-03
Participant
PC-B-L1407
z’-score
PC-B-L1408
z’-score
PC-B-L1409
z’-score
Method
194
0.144
-0.53
0.392
-1.17
1.50
-1.97
ND
217
0.160
0.32
0.440
0.20
1.78
0.24
ICP-MS
226
0.150
-0.23
0.410
-0.65
1.70
-0.36
ICP-MS
317
0.164
0.53
0.463
0.85
1.80
0.39
GFAAS
323
0.151
-0.16
0.485
1.48
2.02
2.10
GFAAS
387
0.181
1.43
0.428
-0.14
1.80
0.41
GFAAS
636
0.167
0.69
0.453
0.57
1.85
0.76
ICP-MS
744
0.145
-0.47
0.452
0.53
1.82
0.53
ND
747
0.159
0.26
0.431
-0.06
1.79
0.31
ICP-MS
1095
0.150
-0.21
0.420
-0.37
1.79
0.31
GFAAS
1109
0.151
-0.18
0.455
0.62
1.81
0.45
ND
1188
0.163
0.48
0.488
1.57
1.81
0.47
ICP-MS (C/R)
1418
0.146
-0.43
0.420
-0.36
1.69
-0.49
ND
1761
LL
---
>LL
---
>LL
---
9674
166
-0.23
LL
---
0.852
-0.98
ICP-MS
1865
2.16
0.37
8.35
-0.03
1.02
0.10
GFAAS
2305
2.26
0.74
8.64
0.26
1.11
0.73
ND
2516
1.28
-2.89
5.98
-2.37
0.493
-3.36
GFAAS
2580
2.01
-0.20
>LL
---
1.20
1.29
GFAAS
2629
2.09
0.11
6.73
-1.63
0.890
-0.73
GFAAS
2763
2.01
-0.18
8.16
-0.22
1.08
0.53
ICP-MS
3150
2.07
0.04
8.83
0.45
1.01
0.07
GFAAS
3167
2.10
0.15
7.86
-0.51
1.00
0.00
GFAAS
3513
2.01
-0.18
9.06
0.67
0.900
-0.66
ICP-MS (C/R)
3853
2.27
0.78
9.43
1.04
0.870
-0.86
ICP-MS
4090
2.16
0.37
8.47
0.09
0.880
-0.79
ICP-MS (C/R)
4953
1.78
-1.04
7.34
-1.03
0.815
-1.22
GFAAS
5556
1.96
-0.35
6.23
-2.13
1.04
0.25
GFAAS
5654
1.99
-0.24
8.50
0.12
1.30
1.96
ICP-MS (C/R)
5691
1.94
-0.44
8.08
-0.30
0.920
-0.53
ICP-MS
5881
2.02
-0.16
9.14
0.75
0.889
-0.73
ICP-MS (C/R)
5955
2.15
0.33
9.20
0.81
1.03
0.20
ND
6511
2.20
0.52
9.11
0.73
1.03
0.20
ND
6702
2.11
0.18
8.59
0.21
0.974
-0.17
GFAAS
7804
2.39
1.22
9.54
1.15
1.26
1.72
ND
8376
2.20
0.52
8.09
-0.29
1.10
0.64
GFAAS
8454
2.05
-0.04
6.20
-2.16
0.980
-0.13
GFAAS
9759
2.04
-0.08
>LL
---
1.03
0.20
GFAAS
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-S-A1407
2.06
0.0377
0.268
1.52 - 2.60
Accepted
---
PC-S-A1408
8.38
0.238
0.983
6.36 - 10.4
Accepted
---
PC-S-A1409
1.00
0.0305
0.148
0.697 - 1.30
Accepted
---
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
12
Statistics
Serum Aluminium (µmol/L)
All methods
PC-S-A1407
PC-S-A1408
32
29
32
Robust mean Algo A
2.06
8.38
1.00
Robust STDev
0.170
1.02
0.138
Median
2.05
8.47
1.01
STDev from MAD
0.156
0.988
0.141
Arithmetic mean
2.06
8.32
1.01
STDev
0.231
1.15
0.173
CV or Variability
8.3%
12.2%
13.8%
PC-S-A1407
PC-S-A1408
PC-S-A1409
15
13
15
Robust mean Algo A
2.05
7.61
1.00
Robust STDev
0.105
1.24
0.133
Median
2.05
7.65
1.01
0.0890
1.36
0.129
Arithmetic mean
2.00
7.72
1.00
STDev
0.248
1.33
0.208
CV or Variability
5.1%
16.3%
13.2%
PC-S-A1407
PC-S-A1408
PC-S-A1409
N
Graphite furnace-AAS
N
STDev from MAD
ICP-MS
N
PC-S-A1409
7
6
7
Robust mean Algo A
2.02
8.63
0.986
Robust STDev
0.128
0.604
0.136
Median
2.01
8.48
0.978
STDev from MAD
0.104
0.534
0.151
Arithmetic mean
2.07
8.79
0.986
STDev
0.253
0.811
0.120
CV or Variability
6.3%
7.0%
13.8%
PC-S-A1407
PC-S-A1408
PC-S-A1409
ICP-MS (collision/reaction cell)
N
5
5
5
2.03
8.90
0.912
0.0378
0.450
0.0349
Robust mean Algo A
Robust STDev
Median
2.02
9.06
0.900
STDev from MAD
0.0330
0.431
0.0297
Arithmetic mean
2.10
8.90
1.00
STDev
0.141
0.397
0.178
CV or Variability
1.9%
5.1%
3.8%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
13
Distribution
Serum Aluminium (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
14
Individual results
Serum Copper (µmol/L)
Round #2014-03
Participant
PC-S-E1407
z’-score
PC-S-E1408
z’-score
PC-S-E1409
z’-score
217
9.30
-0.07
13.2
-0.10
27.7
0.00
FAAS
226
9.65
0.35
13.2
-0.07
29.2
0.89
ICP-MS (C/R)
387
9.92
0.69
20.0
6.72
29.3
1.00
GFAAS
428
9.93
0.70
14.3
0.96
28.0
0.19
ICP-MS (C/R)
636
9.05
-0.39
12.9
-0.44
28.0
0.21
ICP-MS
744
8.07
-1.59
11.7
-1.58
24.2
-2.12
ND
747
9.16
-0.25
12.9
-0.40
26.7
-0.61
ICP-MS
1095
9.90
0.67
14.1
0.80
29.7
1.22
FAAS
1109
10.3
1.11
14.2
0.89
29.0
0.80
ND
1188
9.27
-0.11
13.1
-0.20
26.7
-0.61
ICP-MS (C/R)
1300
9.60
0.30
13.1
-0.24
28.0
0.19
FAAS
1855
11.7
2.94
11.6
-1.71
29.7
1.21
ICP-MS
2305
7.92
-1.78
11.5
-1.79
24.2
-2.16
ND
2516
6.37
-3.70
9.11
-4.21
23.0
-2.87
GFAAS
2580
8.70
-0.82
12.4
-0.91
27.6
-0.06
FAAS
2763
9.00
-0.45
12.9
-0.40
27.5
-0.12
ICP-MS (C/R)
2907
9.73
0.45
14.0
0.73
28.0
0.18
ICP-MS
2982
10.3
1.18
14.3
0.98
28.0
0.16
FAAS
3150
9.30
-0.07
13.4
0.10
26.3
-0.86
FAAS
3211
10.1
0.91
15.2
1.91
29.3
0.98
FAAS
3423
10.8
1.77
14.6
1.33
29.7
1.23
FAAS
3513
9.60
0.30
13.7
0.40
28.6
0.55
ICP-MS
3773
9.30
-0.07
13.6
0.29
28.5
0.49
ICP-MS (C/R)
3853
9.26
-0.12
13.4
0.11
29.7
1.23
ICP-MS
4082
8.98
-0.47
12.9
-0.40
2.68
-15.32
ICP-MS
4090
8.89
-0.58
12.4
-0.89
26.6
-0.69
ICP-MS (C/R)
4953
9.36
0.00
13.5
0.19
28.1
0.23
ICP-MS
5556
9.76
0.49
14.0
0.71
27.9
0.09
FAAS
5591
9.00
-0.45
15.5
2.21
29.6
1.16
GFAAS
5596
8.31
-1.30
12.1
-1.22
24.9
-1.73
ICP-MS (C/R)
5654
9.04
-0.40
12.9
-0.43
27.5
-0.15
ICP-MS (C/R)
5691
9.60
0.30
14.1
0.80
29.2
0.92
ICP-MS
5881
8.87
-0.61
12.7
-0.63
25.8
-1.18
ICP-MS (C/R)
5955
9.05
-0.38
13.0
-0.30
26.3
-0.86
ND
6511
8.99
-0.46
12.8
-0.49
27.2
-0.28
ND
6711
9.42
0.07
13.3
0.05
27.5
-0.14
FAAS
7311
9.79
0.53
13.8
0.54
28.3
0.39
ICP-MS
7804
9.45
0.11
12.2
-1.16
30.2
1.51
ND
8376
11.2
2.27
15.5
2.21
27.5
-0.12
FAAS
8454
9.96
0.74
13.6
0.30
27.2
-0.31
FAAS
8981
9.28
-0.10
14.2
0.91
25.5
-1.35
ND
9759
8.12
-1.53
11.9
-1.43
24.6
-1.91
FAAS
Assigned value
Standard
uncertainty
σ pt
Acceptable range
PC-S-E1407
9.36
0.116
0.801
PC-S-E1408
13.3
0.207
0.973
PC-S-E1409
27.7
0.323
1.60
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
Method
K-S (Lilliefors)
Species
7.74 - 11.0
Accepted
---
11.3 - 15.3
Rejected1
---
24.4 - 31.0
Accepted
--15
Statistics
Serum Copper (µmol/L)
All methods
PC-S-E1407
PC-S-E1408
42
42
41
Robust mean Algo A
9.36
13.3
27.7
Robust STDev
0.601
1.07
1.65
Median
9.30
13.3
27.9
STDev from MAD
0.561
1.07
1.71
Arithmetic mean
9.36
13.4
27.6
STDev
0.890
1.56
1.73
CV or Variability
6.4%
8.1%
6.0%
PC-S-E1407
PC-S-E1408
PC-S-E1409
13
13
13
Robust mean Algo A
9.74
13.7
27.7
Robust STDev
0.744
0.932
0.560
Median
9.76
13.6
27.7
STDev from MAD
0.677
0.799
0.462
Arithmetic mean
9.73
13.7
27.8
STDev
0.815
1.03
1.38
CV or Variability
7.6%
6.8%
2.0%
PC-S-E1407
PC-S-E1408
PC-S-E1409
N
Flame-AAS
N
Graphite furnace-AAS
N
PC-S-E1409
3
3
3
Robust mean Algo A
8.62
14.9
29.2
Robust STDev
1.72
6.19
0.505
Median
9.00
15.5
29.3
STDev from MAD
1.36
6.64
0.400
Arithmetic mean
8.43
14.9
27.3
STDev
1.84
5.46
3.72
CV or Variability
20.0%
41.7%
1.7%
PC-S-E1407
PC-S-E1408
PC-S-E1409
ICP-MS
N
10
10
9
Robust mean Algo A
9.46
13.4
28.4
Robust STDev
0.403
0.667
0.628
Median
9.48
13.4
28.3
STDev from MAD
0.409
0.813
0.496
Arithmetic mean
9.63
13.3
28.5
STDev
0.794
0.750
0.953
CV or Variability
4.3%
5.0%
2.2%
PC-S-E1407
PC-S-E1408
PC-S-E1409
9
9
9
ICP-MS (collision/reaction cell)
N
Robust mean Algo A
9.11
13.0
27.2
Robust STDev
0.382
0.565
1.38
Median
9.04
12.9
27.5
STDev from MAD
0.342
0.496
1.31
Arithmetic mean
9.14
13.0
27.2
STDev
0.472
0.641
1.34
CV or Variability
4.2%
4.4%
5.1%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
16
Distribution
Serum Copper (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
17
Individual results
Serum Manganese (nmol/L)
Round #2014-03
Participant
PC-S-G1407
z’-score
PC-S-G1408
z’-score
PC-S-G1409
z’-score
Method
217
56.0
3.11
73.0
1.50
102
1.22
ICP-MS
323
32.0
-1.23
45.0
-1.75
65.0
-1.81
GFAAS
ICP-MS
747
39.1
0.05
62.5
0.28
93.6
0.53
1109
53.7
2.70
75.5
1.79
107
1.67
ND
1188
42.6
0.69
68.4
0.96
98.3
0.92
ICP-MS (C/R)
2629
39.7
0.16
51.7
-0.98
78.8
-0.68
GFAAS
2763
32.7
-1.10
51.2
-1.03
74.7
-1.02
ICP-MS (C/R)
4090
28.9
-1.78
53.8
-0.73
77.1
-0.82
ND
6511
38.4
-0.07
64.4
0.50
96.5
0.77
ND
8376
40.6
0.32
60.4
0.04
86.8
-0.02
GFAAS
9759
36.4
-0.43
54.6
-0.64
78.3
-0.72
ICP-MS
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-S-G1407
38.8
2.32
5.01
27.8 - 49.8
Accepted
---
PC-S-G1408
60.1
4.16
7.55
42.9 - 77.3
Accepted
---
PC-S-G1409
87.1
5.69
10.8
62.7 - 111
Accepted
---
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
18
Statistics
Serum Manganese (nmol/L)
All methods
PC-S-G1407
PC-S-G1408
11
11
11
Robust mean Algo A
38.8
60.1
87.1
Robust STDev
6.16
11.0
15.1
Median
39.1
60.4
86.8
STDev from MAD
5.19
11.8
14.5
Arithmetic mean
40.0
60.1
87.1
STDev
8.41
9.73
13.3
CV or Variability
15.9%
18.4%
17.3%
PC-S-G1407
PC-S-G1408
PC-S-G1409
3
3
3
Robust mean Algo A
39.3
52.4
76.9
Robust STDev
1.71
8.78
12.5
Median
39.7
51.7
78.8
STDev from MAD
1.35
9.92
11.9
Arithmetic mean
37.4
52.4
76.9
STDev
4.72
7.74
11.0
CV or Variability
4.3%
16.8%
16.3%
PC-S-G1407
PC-S-G1408
PC-S-G1409
N
Graphite furnace-AAS
N
ICP-MS
N
PC-S-G1409
3
3
3
Robust mean Algo A
40.2
63.4
91.3
Robust STDev
5.04
10.5
13.6
Median
39.1
62.5
93.6
STDev from MAD
4.00
11.7
12.5
Arithmetic mean
43.8
63.4
91.3
STDev
10.6
9.23
12.0
CV or Variability
12.5%
16.5%
14.9%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
19
Distribution
Serum Manganese (nmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
20
Individual results
Serum Selenium (µmol/L)
Round #2014-03
Participant
PC-S-E1407
z’-score
PC-S-E1408
z’-score
PC-S-E1409
z’-score
217
0.930
0.09
1.78
0.99
2.77
0.30
Method
ICP-MS
226
0.903
-0.18
1.56
-0.46
2.77
0.32
ICP-MS (C/R)
428
0.833
-0.89
1.60
-0.23
2.58
-0.49
ICP-MS (C/R)
636
0.916
-0.05
1.63
0.03
2.72
0.10
ICP-MS
747
0.873
-0.49
1.55
-0.53
2.59
-0.47
ICP-MS
1095
1.06
1.42
1.59
-0.26
2.52
-0.76
GFAAS
1109
0.941
0.20
1.69
0.41
2.75
0.21
ND
1188
1.02
1.01
1.83
1.31
3.13
1.82
ICP-MS (C/R)
1300
1.00
0.81
1.73
0.64
3.04
1.43
HG-AAS
2305
1.06
1.42
1.65
0.13
2.66
-0.17
ND
2516
0.960
0.40
1.37
-1.71
2.32
-1.61
GFAAS
2763
0.860
-0.62
1.59
-0.26
2.74
0.17
ICP-MS (C/R)
3150
0.980
0.60
1.56
-0.46
2.57
-0.55
GFAAS
3513
0.860
-0.62
1.65
0.13
2.20
-2.12
ICP-MS (C/R)
3773
0.865
-0.57
1.61
-0.16
2.76
0.27
ICP-MS (C/R)
3853
0.950
0.30
1.71
0.53
3.09
1.65
ICP-MS (C/R)
4082
0.871
-0.51
1.63
0.00
2.68
-0.08
ICP-MS
4590
0.927
0.06
1.59
-0.26
2.76
0.25
GFAAS
4953
0.899
-0.22
1.62
-0.06
2.71
0.04
ICP-MS (C/R)
5556
0.906
-0.16
1.41
-1.47
2.22
-2.05
GFAAS
5596
0.852
-0.71
1.54
-0.62
2.53
-0.73
ICP-MS (C/R)
5654
0.913
-0.08
1.87
1.55
3.00
1.27
ICP-MS (C/R)
5691
0.750
-1.74
1.57
-0.39
2.64
-0.25
ICP-MS
5881
0.864
-0.58
1.57
-0.38
2.63
-0.28
ICP-MS (C/R)
5955
0.886
-0.36
1.63
0.00
2.72
0.08
ND
6511
0.973
0.53
1.68
0.30
2.72
0.07
ND
6545
1.00
0.80
1.78
0.99
2.78
0.34
ICP-MS
6711
0.610
-3.17
1.92
1.91
3.22
2.20
ICP-MS
7311
1.02
1.01
1.87
1.58
2.94
1.02
ICP-MS
7804
1.05
1.31
0.970
-4.34
1.54
-4.91
ND
8376
62.1
623.06
104
674.58
182
756.98
GFAAS
8454
0.610
-3.17
1.61
-0.13
2.72
0.08
GFAAS
9759
0.980
0.60
1.58
-0.36
2.56
-0.60
GFAAS
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-S-E1407
0.921
0.0182
0.0965
0.725 - 1.12
Accepted
---
PC-S-E1408
1.63
0.0197
0.151
1.33 - 1.93
Accepted
---
2.23 - 3.17
1
---
PC-S-E1409
2.70
0.0386
0.233
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
Rejected
21
Statistics
Serum Selenium (µmol/L)
All methods
PC-S-E1407
PC-S-E1408
32
32
32
Robust mean Algo A
0.921
1.63
2.70
Robust STDev
0.0824
0.0892
0.175
Median
0.915
1.62
2.72
STDev from MAD
0.0810
0.0822
0.157
Arithmetic mean
0.910
1.62
2.67
STDev
0.107
0.170
0.310
CV or Variability
8.9%
5.5%
6.5%
PC-S-E1407
PC-S-E1408
PC-S-E1409
7
7
7
Robust mean Algo A
0.953
1.57
2.52
Robust STDev
0.0573
0.0298
0.223
Median
0.960
1.58
2.56
STDev from MAD
0.0489
0.0230
0.240
Arithmetic mean
0.918
1.53
2.52
STDev
0.144
0.0980
0.197
CV or Variability
6.0%
1.9%
8.9%
PC-S-E1407
PC-S-E1408
PC-S-E1409
N
Graphite furnace-AAS
N
ICP-MS
N
PC-S-E1409
8
8
8
Robust mean Algo A
0.887
1.72
2.76
Robust STDev
0.117
0.158
0.146
Median
0.895
1.71
2.75
STDev from MAD
0.105
0.159
0.128
Arithmetic mean
0.871
1.72
2.79
STDev
0.135
0.140
0.202
CV or Variability
13.2%
9.2%
5.3%
PC-S-E1407
PC-S-E1408
PC-S-E1409
ICP-MS (collision/reaction cell)
N
11
11
11
Robust mean Algo A
0.884
1.62
2.75
Robust STDev
0.0397
0.0686
0.256
Median
0.865
1.61
2.74
STDev from MAD
0.0470
0.0654
0.232
Arithmetic mean
0.893
1.65
2.74
STDev
0.0539
0.109
0.268
4.5%
4.2%
9.3%
CV or Variability
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
22
Distribution
Serum Selenium (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
23
Individual results
Serum Zinc (µmol/L)
Round #2014-03
Participant
PC-S-E1407
z’-score
PC-S-E1408
z’-score
PC-S-E1409
z’-score
217
11.8
1.02
17.8
0.88
25.4
0.76
Method
FAAS
226
10.7
0.02
16.8
0.25
24.0
0.17
ICP-MS (C/R)
428
11.6
0.87
17.7
0.81
23.8
0.11
ICP-MS (C/R)
636
11.0
0.25
16.6
0.11
24.1
0.20
ICP-MS
744
9.52
-1.10
15.4
-0.58
22.2
-0.60
ND
747
10.0
-0.65
15.5
-0.55
23.1
-0.21
ICP-MS
1095
10.4
-0.28
15.6
-0.49
22.1
-0.64
FAAS
1109
12.2
1.38
19.5
1.90
26.8
1.38
ND
1188
9.96
-0.69
15.4
-0.61
22.4
-0.51
ICP-MS (C/R)
1300
7.03
-3.42
17.1
0.44
23.4
-0.09
FAAS
1855
13.4
2.54
14.3
-1.28
25.4
0.76
ICP-MS
2305
10.7
0.03
15.4
-0.63
22.0
-0.69
ND
2516
10.5
-0.19
16.4
0.00
23.0
-0.26
FAAS
2580
10.4
-0.28
16.4
0.00
23.6
0.00
FAAS
2763
10.3
-0.37
15.9
-0.31
23.1
-0.21
ICP-MS (C/R)
2907
10.2
-0.44
15.3
-0.70
24.4
0.36
ICP-MS
2982
7.12
-3.34
13.2
-1.96
17.7
-2.49
FAAS
3150
10.9
0.19
16.7
0.18
23.5
-0.04
FAAS
3211
11.1
0.37
17.4
0.61
23.7
0.04
FAAS
3423
10.7
0.01
16.4
-0.01
22.9
-0.30
FAAS
3513
11.5
0.75
17.6
0.73
24.5
0.38
ICP-MS
3773
10.5
-0.15
17.2
0.48
24.7
0.46
ICP-MS (C/R)
3853
11.2
0.42
17.2
0.51
25.5
0.82
ICP-MS
4082
10.2
-0.47
16.2
-0.12
22.8
-0.34
ICP-MS
4090
9.57
-1.06
15.4
-0.60
22.3
-0.57
ICP-MS (C/R)
4953
11.0
0.32
17.2
0.50
24.8
0.51
ICP-MS
5556
10.9
0.14
16.8
0.25
23.2
-0.15
FAAS
5591
11.5
0.75
16.8
0.24
23.9
0.13
FAAS
5596
10.1
-0.59
16.1
-0.18
22.3
-0.55
ICP-MS (C/R)
5654
10.6
-0.09
17.5
0.70
24.4
0.35
ICP-MS (C/R)
5691
11.3
0.56
17.9
0.92
25.3
0.72
ICP-MS
5881
9.95
-0.70
15.7
-0.42
22.1
-0.65
ICP-MS (C/R)
5955
9.93
-0.72
15.7
-0.43
22.2
-0.60
ND
6511
10.7
-0.04
16.4
-0.02
23.2
-0.19
ND
6711
12.0
1.19
17.1
0.45
25.8
0.92
ICP-MS
7311
11.2
0.45
17.2
0.47
24.4
0.33
ICP-MS
7804
LL
---
GFAAS
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-U-R1407
0.176
0.00828
0.0187
0.135 - 0.217
Rejected1
---
PC-U-R1408
0.684
0.0241
0.0578
0.559 - 0.809
Rejected1
---
PC-U-R1409
11.3
0.198
0.877
9.50 - 13.1
Accepted
---
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
33
Statistics
Urine Copper (µmol/L)
All methods
PC-U-R1407
PC-U-R1408
25
27
26
Robust mean Algo A
0.176
0.684
11.3
Robust STDev
0.0331
0.100
0.809
Median
0.173
0.680
11.2
STDev from MAD
0.0301
0.0983
0.714
Arithmetic mean
0.220
0.708
11.5
STDev
0.185
0.154
1.05
CV or Variability
18.8%
14.6%
7.2%
PC-U-R1407
PC-U-R1408
PC-U-R1409
4
4
3
Robust mean Algo A
0.159
0.641
11.4
Robust STDev
0.0326
0.0948
0.859
Median
0.161
0.655
11.6
STDev from MAD
0.0257
0.0820
0.680
N
Graphite furnace-AAS
N
PC-U-R1409
Arithmetic mean
0.156
0.641
11.3
STDev
0.0341
0.0836
0.974
CV or Variability
20.5%
14.8%
7.5%
PC-U-R1407
PC-U-R1408
PC-U-R1409
ICP-MS
N
10
10
10
Robust mean Algo A
0.202
0.708
11.3
Robust STDev
0.0304
0.0552
0.633
Median
0.199
0.699
11.3
STDev from MAD
0.0274
0.0465
0.738
Arithmetic mean
0.278
0.718
11.4
STDev
0.247
0.0681
0.668
CV or Variability
15.1%
7.8%
5.6%
PC-U-R1407
PC-U-R1408
PC-U-R1409
ICP-MS (collision/reaction cell)
N
7
7
6
Robust mean Algo A
0.160
0.655
10.8
Robust STDev
0.0232
0.0869
0.355
Median
0.168
0.658
10.9
STDev from MAD
0.0225
0.0797
0.297
Arithmetic mean
0.143
0.652
10.8
STDev
0.0541
0.0928
0.466
CV or Variability
14.5%
13.3%
3.3%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
34
Distribution
Urine Copper (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
35
Individual results
Urine Fluoride (µmol/L)
Round #2014-03
Participant
PC-U-F1407
z’-score
PC-U-F1408
z’-score
PC-U-F1409
z’-score
Method
176
208
-0.01
90.5
-0.17
1160
-0.34
FSE
1095
187
-1.63
78.0
-1.99
1180
0.00
FSE
1418
199
-0.66
89.0
-0.40
1210
0.39
FSE
1476
195
-1.01
84.0
-1.12
1080
-1.48
FSE
2629
189
-1.43
89.5
-0.32
1160
-0.34
FSE
4604
211
0.24
92.3
0.09
1190
0.14
FSE
5132
206
-0.16
90.7
-0.14
1130
-0.69
ND
5881
208
0.03
87.0
-0.68
1330
2.25
FSE
6200
212
0.28
93.7
0.29
1240
0.88
FSE
6234
213
0.39
95.2
0.51
1220
0.62
FSE
6545
209
0.09
95.1
0.49
1210
0.46
FSE
6702
214
0.46
91.7
0.00
1140
-0.60
FSE
7269
208
0.00
93.0
0.19
1220
0.59
FSE
8701
218
0.79
95.5
0.54
1240
0.91
ND
9759
208
-0.01
100
1.21
1050
-1.96
FSE
9908
214
0.44
95.3
0.52
1170
-0.08
FSE
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
208
2.08
12.7
182 - 234
Accepted
---
PC-U-F1408
91.7
1.36
6.75
77.9 - 105
Accepted
---
PC-U-F1409
1180
16.6
63.0
1050 - 1310
Accepted
---
PC-U-F1407
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
36
Statistics
Urine Fluoride (µmol/L)
All methods
PC-U-F1407
PC-U-F1408
N
16
16
16
Robust mean Algo A
208
91.7
1180
Robust STDev
6.65
4.36
53.0
Median
208
92.0
1180
STDev from MAD
6.05
4.56
51.2
Arithmetic mean
206
91.3
1180
STDev
8.95
5.21
64.6
CV or Variability
3.2%
4.8%
4.5%
PC-U-F1409
Fluoride specific electrode
PC-U-F1409
PC-U-F1407
PC-U-F1408
N
14
14
14
Robust mean Algo A
207
91.5
1180
Robust STDev
6.43
4.54
47.7
Median
208
92.0
1180
STDev from MAD
6.05
4.56
44.5
Arithmetic mean
205
91.0
1180
STDev
8.98
5.46
66.3
CV or Variability
3.1%
5.0%
4.0%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
37
Distribution
Urine Fluoride (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
38
Individual results
Urine Inorganic arsenic (µmol/L)
Round #2014-03
*
Participant
PC-U-S1407
z’-score
PC-U-S1408
z’-score
PC-U-S1409
z’-score
Method
217
0.380
2.28
1.34
0.00
6.31
0.07
GFAAS
317
0.280
0.00
1.24
-0.71
6.65
0.62
GFAAS
428
0.259
-0.48
1.40
0.44
5.77
-0.82
ICP-MS (C/R)
730
0.302
0.49
1.39
0.34
6.91
1.05
ICP-MS (C/R)
747
0.293
0.30
1.39
0.35
6.48
0.34
ICP-MS (C/R)
1095
0.280
0.00
1.39
0.35
6.78
0.83
GFAAS
1418
0.269
-0.26
1.35
0.10
5.82
-0.74
HG-AAS
1476
0.450
3.87
1.33
-0.07
4.99
-2.09
ICP-MS
1820
0.268
-0.27
1.33
-0.07
7.14
1.42
GFAAS
1827
0.243
-0.84
1.26
-0.57
5.99
-0.46
ICP-MS (C/R)
1865
0.195
-1.94
0.878
-3.27
6.50
0.38
HG-AAS
2580
0.275
-0.11
1.40
0.45
6.86
0.97
GFAAS
2978
0.274
-0.15
1.28
-0.42
5.87
-0.65
ICP-MS
3215
0.330
1.14
1.51
1.20
>LL
---
GFAAS
3423
0.240
-0.91
1.32
-0.13
6.37
0.16
HG-AAS
3853
0.327
1.07
1.37
0.18
6.30
0.04
ICP-MS (C/R)
5375
0.253
-0.61
1.39
0.35
7.22
1.55
ICP-MS
5495
0.315
0.79
1.47
0.89
6.07
-0.32
ICP-MS (C/R)
5691
0.320
0.91
1.17
-1.20
5.89
-0.62
ND
5881
0.237
-0.97
1.17
-1.21
6.10
-0.28
HG-AAS
6511
0.272
-0.18
1.38
0.30
6.27
-0.01
ND
6545
0.290
0.23
1.33
-0.07
5.97
-0.49
ICP-MS (C/R)
7162
0.160
-2.73
1.12
-1.56
5.97
-0.49
GFAAS
8701
0.284
0.09
1.43
0.62
5.96
-0.51
ND
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
PC-U-S1407
0.280*
0.00979
0.0409
0.196 - 0.364
Accepted
MAA added
PC-U-S1408
1.34
0.0206
0.140
1.06 - 1.62
Accepted
Workers Profile
PC-U-S1409
6.27
0.123
0.600
5.05 - 7.49
Accepted
As+3 added
Species
The assigned value is outside the concentration range of our scope of accreditation.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
39
Statistics
Urine Inorganic arsenic (µmol/L)
All methods
PC-U-S1407
PC-U-S1408
24
24
23
Robust mean Algo A
0.280
1.34
6.27
Robust STDev
0.0384
0.0809
0.473
Median
0.278
1.35
6.27
STDev from MAD
0.0361
0.0727
0.451
N
PC-U-S1409
Arithmetic mean
0.283
1.32
6.27
STDev
0.0571
0.132
0.512
CV or Variability
13.7%
6.0%
7.5%
PC-U-S1407
PC-U-S1408
PC-U-S1409
7
7
6
Robust mean Algo A
0.281
1.34
6.64
Robust STDev
0.0222
0.111
0.430
Median
0.280
1.34
6.72
STDev from MAD
0.0178
0.0949
0.409
Graphite furnace-AAS
N
Arithmetic mean
0.282
1.33
6.62
STDev
0.0671
0.125
0.418
7.9%
8.3%
6.5%
PC-U-S1407
PC-U-S1408
PC-U-S1409
CV or Variability
Hydride generation-AAS
N
4
4
4
Robust mean Algo A
0.238
1.22
6.20
Robust STDev
0.0299
0.164
0.343
Median
0.239
1.25
6.23
STDev from MAD
0.0232
0.136
0.298
Arithmetic mean
0.235
1.18
6.20
STDev
0.0304
0.217
0.302
CV or Variability
12.6%
13.4%
5.5%
PC-U-S1407
PC-U-S1408
PC-U-S1409
ICP-MS
N
3
3
3
Robust mean Algo A
0.282
1.33
6.03
Robust STDev
0.0386
0.0617
1.27
Median
0.274
1.33
5.87
STDev from MAD
0.0306
0.0722
1.31
Arithmetic mean
0.326
1.33
6.03
STDev
0.108
0.0544
1.12
CV or Variability
13.7%
4.6%
21.1%
PC-U-S1407
PC-U-S1408
PC-U-S1409
7
7
7
ICP-MS (collision/reaction cell)
N
Robust mean Algo A
0.290
1.38
6.16
Robust STDev
0.0332
0.0400
0.332
Median
0.293
1.39
6.07
STDev from MAD
0.0322
0.0328
0.331
Arithmetic mean
0.290
1.37
6.21
STDev
0.0297
0.0640
0.387
CV or Variability
11.5%
2.9%
5.4%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
40
Distribution
Urine Inorganic arsenic (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
41
Individual results
Urine Iodide (µmol/L)
Round #2014-03
Participant
PC-U-I1407
z’-score
PC-U-I1408
z’-score
PC-U-I1409
z’-score
217
1.53
0.46
0.900
0.20
2.73
0.36
Method
ICP-MS
428
1.47
0.09
0.898
0.18
2.74
0.41
ICP-MS (C/R)
747
1.39
-0.46
0.841
-0.45
2.54
-0.33
ICP-MS
1095
1.75
1.90
0.923
0.45
3.07
1.60
ICP-MS (C/R)
1855
1.65
1.28
0.953
0.79
3.01
1.38
ICP-MS
2629
1340
8783.51
788
8733.80
2530
9206.59
ND
2763
1.45
-0.07
0.875
-0.08
2.59
-0.15
ICP-MS
2951
1.38
-0.53
0.900
0.20
2.38
-0.91
COLOR
3187
1.36
-0.66
0.809
-0.81
2.56
-0.26
ICP-MS
3513
1.27
-1.25
0.770
-1.24
2.29
-1.24
ICP-MS
4708
1.49
0.20
0.895
0.14
2.73
0.36
ICP-MS
5881
1.84
2.53
1.05
1.87
3.28
2.36
ICP-MS (C/R)
6200
1.51
0.35
0.932
0.55
2.75
0.43
ICP-MS
6511
1.36
-0.64
0.872
-0.11
2.58
-0.19
ND
6545
1.46
0.00
0.840
-0.47
2.58
-0.18
ICP-MS
8981
1.24
-1.44
0.760
-1.35
2.25
-1.38
ND
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-U-I1407
1.46
0.0435
0.146
1.16 - 1.76
Accepted
---
PC-U-I1408
0.882
0.0185
0.0882
0.702 - 1.06
Accepted
---
PC-U-I1409
2.63
0.0785
0.263
2.08 - 3.18
Accepted
---
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
42
Statistics
Urine Iodide (µmol/L)
All methods
PC-U-I1407
PC-U-I1408
15
15
15
Robust mean Algo A
1.46
0.882
2.63
Robust STDev
0.135
0.0574
0.243
Median
1.46
0.895
2.59
STDev from MAD
0.119
0.0549
0.226
N
PC-U-I1409
Arithmetic mean
1.48
0.881
2.67
STDev
0.167
0.0732
0.283
CV or Variability
9.2%
6.5%
9.2%
PC-U-I1407
PC-U-I1408
PC-U-I1409
9
9
9
Robust mean Algo A
1.46
0.871
2.63
Robust STDev
0.108
0.0608
0.184
Median
1.46
0.875
2.59
STDev from MAD
0.104
0.0519
0.208
ICP-MS
N
Arithmetic mean
1.46
0.868
2.64
STDev
0.110
0.0589
0.197
CV or Variability
7.4%
7.0%
7.0%
PC-U-I1407
PC-U-I1408
PC-U-I1409
ICP-MS (collision/reaction cell)
N
3
3
3
Robust mean Algo A
1.71
0.933
3.03
Robust STDev
0.177
0.0462
0.306
Median
1.75
0.923
3.07
STDev from MAD
0.140
0.0366
0.306
Arithmetic mean
1.69
0.957
3.03
STDev
0.193
0.0816
0.269
CV or Variability
10.4%
5.0%
10.1%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
43
Distribution
Urine Iodide (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
44
Individual results
Urine Lead (µmol/L)
Round #2014-03
Participant
PC-U-P1407
z’-score
PC-U-P1408
z’-score
PC-U-P1409
z’-score
Method
176
0.555
0.21
0.285
1.14
4.68
1.13
ICP-MS
194
0.472
-1.69
0.234
-1.20
3.74
-1.61
ND
217
0.560
0.32
0.260
0.00
4.58
0.85
ICP-MS
747
0.547
0.02
0.258
-0.09
4.08
-0.62
ICP-MS
1095
0.620
1.69
0.270
0.46
4.21
-0.23
ICP-MS (C/R)
1109
0.533
-0.30
0.252
-0.35
4.13
-0.48
ND
1855
0.545
-0.01
0.256
-0.19
4.36
0.21
ICP-MS
2182
4.34
86.78
0.271
0.50
0.598
-10.83
GFAAS
3167
0.540
-0.14
0.260
0.00
4.54
0.73
GFAAS
3187
0.543
-0.07
0.260
0.00
4.24
-0.15
ICP-MS
3211
0.557
0.25
0.270
0.46
4.17
-0.36
GFAAS
3423
0.550
0.10
0.256
-0.17
4.51
0.65
GFAAS
3776
3.52
67.91
2.94
123.59
7.53
9.51
ND
3853
0.532
-0.32
0.254
-0.28
4.15
-0.42
ICP-MS
3970
0.512
-0.79
0.232
-1.31
6.15
5.45
GFAAS
4090
0.550
0.09
0.243
-0.79
4.36
0.21
ICP-MS (C/R)
4708
0.572
0.59
0.270
0.46
4.47
0.53
ICP-MS
4953
0.555
0.21
0.263
0.12
4.41
0.36
ICP-MS
5591
0.580
0.78
0.280
0.92
4.47
0.53
ICP-MS
5654
0.481
-1.50
0.246
-0.66
4.38
0.28
ICP-MS (C/R)
5691
0.540
-0.14
0.260
0.00
4.32
0.09
ICP-MS
5881
0.529
-0.38
0.250
-0.45
4.02
-0.80
ICP-MS (C/R)
6511
0.547
0.03
0.265
0.23
4.14
-0.43
ND
6545
0.540
-0.14
0.260
0.00
4.21
-0.23
ICP-MS
7111
0.547
0.02
0.266
0.28
4.30
0.02
ICP-MS
7804
0.648
2.33
0.0541
-9.51
3.35
-2.75
ND
9674
0.516
-0.68
0.247
-0.62
3.71
-1.71
GFAAS
9759
>LL
---
0.385
5.78
>LL
---
GFAAS
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-U-P1407
0.546
0.00419
0.0436
0.458 - 0.634
Rejected1
---
PC-U-P1408
0.260
0.00353
0.0213
0.217 - 0.303
Rejected1
---
1
---
PC-U-P1409
4.29
0.0662
0.334
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
3.61 - 4.97
Rejected
45
Statistics
Urine Lead (µmol/L)
All methods
PC-U-P1407
PC-U-P1408
25
28
27
Robust mean Algo A
0.546
0.260
4.29
Robust STDev
0.0168
0.0150
0.275
Median
0.547
0.260
4.30
STDev from MAD
0.0148
0.0147
0.255
Arithmetic mean
0.547
0.351
4.29
STDev
0.0358
0.509
1.07
3.1%
5.8%
6.4%
PC-U-P1407
PC-U-P1408
PC-U-P1409
5
7
6
Robust mean Algo A
0.535
0.261
4.27
Robust STDev
0.0229
0.0182
0.750
Median
0.540
0.260
4.34
STDev from MAD
0.0252
0.0159
0.618
3.95
N
CV or Variability
Graphite furnace-AAS
N
PC-U-P1409
Arithmetic mean
0.535
0.274
STDev
0.0202
0.0507
1.84
4.3%
7.0%
17.6%
PC-U-P1407
PC-U-P1408
PC-U-P1409
CV or Variability
ICP-MS
N
12
12
12
Robust mean Algo A
0.549
0.262
4.35
Robust STDev
0.0115
0.00530
0.191
Median
0.547
0.260
4.34
STDev from MAD
0.0111
0.00501
0.191
Arithmetic mean
0.551
0.264
4.36
STDev
0.0139
0.00951
0.176
2.1%
2.0%
4.4%
PC-U-P1407
PC-U-P1408
PC-U-P1409
CV or Variability
ICP-MS (collision/reaction cell)
N
4
4
4
Robust mean Algo A
0.544
0.249
4.26
Robust STDev
0.0641
0.00642
0.156
Median
0.540
0.248
4.29
STDev from MAD
0.0515
0.00533
0.130
Arithmetic mean
0.545
0.252
4.24
STDev
0.0579
0.0122
0.170
CV or Variability
11.8%
2.6%
3.7%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
46
Distribution
Urine Lead (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
47
Individual results
Urine Mercury (nmol/L)
Round #2014-03
Participant
PC-U-H1407
z’-score
PC-U-H1408
z’-score
PC-U-H1409
z’-score
Method
176
74.8
0.67
414
0.52
1380
0.82
ICP-MS
217
65.0
-0.18
347
-0.88
1340
0.53
ICP-MS
428
85.2
1.58
488
2.07
1510
1.70
ICP-MS (C/R)
720
34.9
-2.81
309
-1.67
1220
-0.30
CV
744
79.1
1.05
465
1.60
1650
2.61
ND
1095
69.0
0.17
396
0.15
1250
-0.09
CV
1109
65.8
-0.11
401
0.26
1260
-0.02
ND
1156
24.4
-3.73
202
-3.91
646
-4.16
ND
1418
61.9
-0.45
343
-0.95
1090
-1.16
ND
1865
74.3
0.63
419
0.62
1290
0.21
CV
2629
58.3
-0.77
367
-0.46
1260
0.01
ICP-MS (C/R)
2982
61.0
-0.53
410
0.44
1040
-1.51
CV
3187
60.7
-0.56
366
-0.48
1140
-0.81
ICP-MS
3468
80.7
1.18
401
0.24
1520
1.75
GA-AAS
3513
66.0
-0.10
358
-0.65
1160
-0.68
ICP-MS
3853
69.2
0.18
404
0.31
1320
0.44
ICP-MS
4604
65.0
-0.18
25.4
-7.60
136
-7.63
CV
4708
68.9
0.16
409
0.42
1330
0.44
ICP-MS
4953
71.3
0.37
408
0.40
1370
0.75
ICP-MS
5029
50.5
-1.45
231
-3.31
718
-3.68
ND
5491
60.0
-0.62
428
0.82
1420
1.07
CV
5591
65.3
-0.16
369
-0.43
1250
-0.10
ICP-MS
5654
94.2
2.37
467
1.62
1490
1.54
ICP-MS (C/R)
5691
69.0
0.17
361
-0.59
1380
0.79
ICP-MS
5881
64.8
-0.20
376
-0.26
1230
-0.23
ICP-MS (C/R)
6200
61.6
-0.48
356
-0.70
1220
-0.29
ICP-MS
6210
66.3
-0.07
361
-0.59
1200
-0.42
ND
6511
106
3.41
430
0.86
1480
1.52
ND
6545
70.0
0.25
489
2.08
1670
2.78
ICP-MS
6702
70.5
0.30
398
0.19
1380
0.79
CV
6794
73.8
0.58
393
0.08
1290
0.18
GA-AAS
6892
65.5
-0.14
360
-0.61
1200
-0.43
ND
6920
56.8
-0.90
927
11.24
323
-6.36
ND
7184
70.4
0.29
422
0.69
1350
0.63
CV
7190
62.8
-0.37
388
-0.01
>LL
---
ICP-MS (C/R)
7269
68.0
0.08
397
0.17
1210
-0.35
CV
7864
69.0
0.17
333
-1.17
1150
-0.76
ND
8701
61.2
-0.51
345
-0.92
1150
-0.72
ND
9674
66.8
-0.03
370
-0.40
962
-2.02
CV
9759
84.8
1.54
439
1.04
>LL
---
GA-AAS
9777
68.7
0.14
383
-0.12
1270
0.09
GA-AAS
PC-U-H1407
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
67.1
1.38
11.4
44.2 - 90.0
Rejected1
---
1
PC-U-H1408
389
9.12
46.9
293 - 485
Rejected
---
PC-U-H1409
1260
34.7
143
965 - 1550
Accepted
---
Criteria of homogeneity: according to ISO/CEI 17043 criteria, mercury in material PC-U-H1407 doesn’t respect acceptable heterogeneity. The
statistical data are produced as an indication only.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
48
Statistics
Urine Mercury (nmol/L)
All methods
PC-U-H1407
PC-U-H1408
41
41
39
Robust mean Algo A
67.1
389
1260
Robust STDev
7.06
46.7
173
Median
66.8
393
1260
STDev from MAD
6.65
46.9
163
Arithmetic mean
67.4
389
1210
STDev
13.3
117
308
CV or Variability
10.5%
12.0%
13.7%
PC-U-H1407
PC-U-H1408
PC-U-H1409
10
10
10
Robust mean Algo A
66.6
393
1200
Robust STDev
5.35
33.6
195
Median
67.4
398
1230
STDev from MAD
4.52
33.9
197
Arithmetic mean
64.0
357
1120
STDev
11.1
122
376
CV or Variability
8.0%
8.5%
16.2%
PC-U-H1407
PC-U-H1408
PC-U-H1409
N
Cold vapor
N
Gold amalgamation-AAS
N
PC-U-H1409
4
4
3
Robust mean Algo A
77.0
398
1290
Robust STDev
8.11
15.5
23.0
Median
77.2
397
1290
STDev from MAD
8.13
12.7
18.2
Arithmetic mean
77.0
404
1360
STDev
7.15
24.3
138
CV or Variability
10.5%
3.9%
1.8%
PC-U-H1407
PC-U-H1408
PC-U-H1409
ICP-MS
N
11
11
11
Robust mean Algo A
67.6
382
1310
Robust STDev
4.18
31.0
95.2
Median
68.9
369
1330
STDev from MAD
4.30
31.9
82.9
Arithmetic mean
67.4
389
1320
STDev
4.18
41.4
143
CV or Variability
6.2%
8.1%
7.3%
PC-U-H1407
PC-U-H1408
PC-U-H1409
5
5
4
1370
ICP-MS (collision/reaction cell)
N
Robust mean Algo A
68.9
401
Robust STDev
11.0
37.5
168
Median
64.8
388
1370
STDev from MAD
9.61
31.8
185
Arithmetic mean
73.1
417
1370
STDev
15.7
55.9
148
CV or Variability
16.0%
9.4%
12.3%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
49
Distribution
Urine Mercury (nmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
50
Individual results
Urine Selenium (µmol/L)
Round #2014-03
Participant
PC-U-N1407
z’-score
PC-U-N1408
z’-score
PC-U-N1409
z’-score
Method
747
2.95
-0.10
1.23
0.16
1.78
0.00
ICP-MS
3187
2.89
-0.24
1.14
-0.21
1.70
-0.27
ICP-MS
3423
2.37
-1.50
1.03
-0.66
1.81
0.11
HG-AAS
3853
3.34
0.85
1.30
0.45
1.92
0.48
ICP-MS (C/R)
4090
2.99
0.00
1.20
0.04
1.73
-0.17
ICP-MS (C/R)
5691
2.72
-0.65
1.11
-0.33
1.51
-0.93
ICP-MS
5881
3.11
0.28
1.17
-0.10
1.76
-0.05
ICP-MS (C/R)
6511
3.77
1.88
1.58
1.62
2.31
1.83
ND
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-U-N1407
2.99
0.145
0.388
2.16 - 3.82
Accepted
Workers Profile
PC-U-N1408
1.19
0.0460
0.239
0.703 - 1.68
Accepted
Se+4 added
PC-U-N1409
1.78
0.0451
0.288
1.20 - 2.36
Accepted
Workers Profile
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
51
Statistics
Urine Selenium (µmol/L)
All methods
PC-U-N1407
PC-U-N1408
8
8
8
Robust mean Algo A
2.99
1.19
1.78
Robust STDev
0.329
0.104
0.102
Median
2.97
1.18
1.77
STDev from MAD
0.286
0.0890
0.0847
N
PC-U-N1409
Arithmetic mean
3.02
1.22
1.82
STDev
0.415
0.168
0.232
CV or Variability
11.0%
8.8%
5.7%
PC-U-N1407
PC-U-N1408
PC-U-N1409
3
3
3
Robust mean Algo A
2.87
1.15
1.67
Robust STDev
0.112
0.0562
0.150
Median
2.89
1.14
1.70
0.0890
0.0445
0.119
ICP-MS
N
STDev from MAD
Arithmetic mean
2.85
1.16
1.66
STDev
0.119
0.0625
0.139
CV or Variability
3.9%
4.9%
9.0%
PC-U-N1407
PC-U-N1408
PC-U-N1409
ICP-MS (collision/reaction cell)
N
3
3
3
Robust mean Algo A
3.15
1.21
1.78
Robust STDev
0.202
0.0645
0.0640
Median
3.11
1.20
1.76
STDev from MAD
0.171
0.0511
0.0507
Arithmetic mean
3.15
1.22
1.80
STDev
0.178
0.0698
0.101
CV or Variability
6.4%
5.3%
3.6%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
52
Distribution
Urine Selenium (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
53
Individual results
Urine Total arsenic (µmol/L)
Round #2014-03
Participant
PC-U-S1407
z’-score
PC-U-S1408
z’-score
PC-U-S1409
z’-score
176
0.387
0.36
1.55
0.89
6.67
0.32
Method
ICP-MS
730
0.387
0.36
1.39
-0.42
6.93
0.81
ICP-MS (C/R)
ICP-MS
747
0.338
-0.82
1.34
-0.82
5.80
-1.38
1109
0.448
1.83
1.71
2.17
7.41
1.75
ND
1476
0.360
-0.29
1.39
-0.41
5.49
-1.98
ICP-MS
1827
0.329
-1.03
1.32
-0.98
5.98
-1.03
ICP-MS (C/R)
1865
0.386
0.33
1.53
0.72
6.89
0.73
ICP-MS (C/R)
2182
0.423
1.23
1.52
0.67
6.81
0.58
GFAAS
2937
0.493
2.90
1.60
1.33
7.10
1.15
ICP-MS
2978
0.367
-0.12
1.41
-0.21
6.19
-0.62
ICP-MS
3187
0.377
0.12
1.43
-0.08
6.22
-0.56
ICP-MS
3423
0.347
-0.60
1.41
-0.21
6.30
-0.41
HG-AAS
3513
0.360
-0.29
1.47
0.25
6.36
-0.29
ICP-MS
3853
0.372
0.00
1.52
0.62
6.74
0.44
ICP-MS (C/R)
4708
0.370
-0.05
1.41
-0.25
6.58
0.14
ICP-MS
4953
0.342
-0.73
1.44
0.01
6.63
0.24
ICP-MS (C/R)
5375
0.343
-0.70
1.40
-0.33
7.24
1.42
ICP-MS
5495
0.400
0.67
1.48
0.34
6.13
-0.74
ICP-MS (C/R)
5591
0.403
0.74
1.61
1.39
7.48
1.89
ICP-MS
5654
0.349
-0.55
1.29
-1.19
5.25
-2.45
ICP-MS (C/R)
5691
0.380
0.19
1.45
0.08
6.22
-0.56
ND
5881
0.383
0.27
1.51
0.59
6.68
0.33
ICP-MS (C/R)
6511
0.382
0.23
1.43
-0.04
6.59
0.16
ND
6545
0.370
-0.05
1.43
-0.08
6.31
-0.39
ICP-MS (C/R)
6892
0.400
0.67
1.34
-0.82
5.45
-2.06
ND
7864
0.334
-0.91
1.40
-0.33
6.45
-0.12
ND
9674
0.266
-2.55
1.31
-1.08
6.90
0.76
GFAAS
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
PC-U-S1407
0.372
0.00764
0.0410
0.289 - 0.455
Accepted
MAA added
PC-U-S1408
1.44
0.0205
0.120
1.20 - 1.68
Accepted
Workers Profile
PC-U-S1409
6.51
0.127
0.498
5.48 - 7.54
Accepted
As+3 added
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
Species
54
Statistics
Urine Total arsenic (µmol/L)
All methods
PC-U-S1407
PC-U-S1408
27
27
27
Robust mean Algo A
0.372
1.44
6.51
Robust STDev
0.0317
0.0851
0.526
Median
0.372
1.43
6.58
STDev from MAD
0.0343
0.0757
0.515
N
PC-U-S1409
Arithmetic mean
0.374
1.45
6.47
STDev
0.0418
0.0977
0.567
8.5%
5.9%
8.1%
PC-U-S1407
PC-U-S1408
PC-U-S1409
10
10
10
Robust mean Algo A
0.370
1.44
6.51
Robust STDev
0.0237
0.0675
0.718
Median
0.369
1.42
6.47
STDev from MAD
0.0201
0.0593
0.673
CV or Variability
ICP-MS
N
Arithmetic mean
0.380
1.46
6.51
STDev
0.0442
0.0938
0.634
6.4%
4.7%
11.0%
PC-U-S1407
PC-U-S1408
PC-U-S1409
CV or Variability
ICP-MS (collision/reaction cell)
N
9
9
9
Robust mean Algo A
0.370
1.43
6.47
Robust STDev
0.0249
0.0972
0.429
Median
0.372
1.44
6.63
STDev from MAD
0.0224
0.105
0.435
Arithmetic mean
0.369
1.43
6.39
STDev
0.0238
0.0857
0.540
6.7%
6.8%
6.6%
CV or Variability
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
55
Distribution
Urine Total arsenic (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
56
Individual results
Urine Zinc (µmol/L)
Round #2014-03
Participant
PC-U-R1407
z’-score
PC-U-R1408
z’-score
PC-U-R1409
z’-score
Method
176
4.42
0.39
4.91
0.04
24.6
0.24
ICP-MS
747
4.29
0.05
4.99
0.22
25.5
0.67
ICP-MS
1095
4.45
0.47
5.17
0.63
24.9
0.38
FAAS
1109
4.61
0.90
5.40
1.15
26.0
0.90
ND
1188
4.01
-0.68
4.33
-1.25
22.1
-0.95
ICP-MS (C/R)
1418
4.05
-0.57
4.36
-1.19
22.0
-0.99
ICP-MS (C/R)
2629
3.41
-2.26
4.03
-1.92
21.1
-1.45
ICP-OES
2763
4.17
-0.26
4.88
-0.02
24.0
-0.05
ICP-MS (C/R)
3187
3.83
-1.16
4.36
-1.19
23.5
-0.29
ICP-MS
3211
4.60
0.87
5.50
1.37
25.3
0.57
FAAS
3423
5.06
2.07
5.79
2.01
26.6
1.20
FAAS
3513
3.90
-0.97
4.60
-0.65
25.6
0.71
ICP-MS
3853
4.04
-0.60
4.76
-0.29
23.0
-0.51
ICP-MS
4090
3.27
-2.63
3.98
-2.04
23.4
-0.32
ICP-MS (C/R)
4708
4.24
-0.08
4.96
0.16
24.4
0.14
ICP-MS
4953
4.11
-0.41
4.82
-0.17
23.2
-0.42
ICP-MS
5591
4.00
-0.71
4.90
0.02
23.4
-0.33
FAAS
5691
4.30
0.08
4.80
-0.20
24.4
0.14
ICP-MS
5881
3.68
-1.54
4.37
-1.16
21.9
-1.03
ICP-MS (C/R)
6511
4.62
0.91
5.32
0.96
26.3
1.07
ND
7804
4.79
1.36
1.45
-7.70
6.52
-8.36
ND
8376
4.28
0.02
5.10
0.46
24.5
0.18
FAAS
8454
4.90
1.66
5.37
1.07
24.5
0.19
FAAS
8981
4.28
0.03
6.11
2.73
22.6
-0.71
ND
9759
6.38
5.56
6.69
4.03
26.5
1.13
FAAS
Assigned value
Standard
uncertainty
σ pt
Acceptable range
K-S (Lilliefors)
Species
PC-U-R1407
4.27
0.109
0.364
3.51 - 5.03
Accepted
---
PC-U-R1408
4.89
0.159
0.418
4.00 - 5.78
Accepted
---
19.9 - 28.3
1
---
PC-U-R1409
24.1
0.438
2.06
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
Rejected
57
Statistics
Urine Zinc (µmol/L)
All methods
PC-U-R1407
PC-U-R1408
25
25
25
Robust mean Algo A
4.27
4.89
24.1
Robust STDev
0.435
0.637
1.75
Median
4.28
4.90
24.4
STDev from MAD
0.411
0.697
1.77
23.4
N
PC-U-R1409
Arithmetic mean
4.31
4.84
STDev
0.606
0.943
3.84
CV or Variability
10.2%
13.0%
7.3%
PC-U-R1407
PC-U-R1408
PC-U-R1409
7
7
7
Robust mean Algo A
4.66
5.40
25.0
Robust STDev
0.523
0.437
0.803
Median
4.60
5.37
24.9
STDev from MAD
0.478
0.405
0.615
25.1
Flame-AAS
N
Arithmetic mean
4.81
5.50
STDev
0.781
0.598
1.15
CV or Variability
11.2%
8.1%
3.2%
PC-U-R1407
PC-U-R1408
PC-U-R1409
ICP-MS
N
8
8
8
Robust mean Algo A
4.15
4.80
24.3
Robust STDev
0.222
0.186
1.11
Median
4.18
4.81
24.4
STDev from MAD
0.193
0.187
1.48
Arithmetic mean
4.14
4.77
24.3
STDev
0.207
0.208
0.979
CV or Variability
5.3%
3.9%
4.6%
PC-U-R1407
PC-U-R1408
PC-U-R1409
ICP-MS (collision/reaction cell)
N
5
5
5
Robust mean Algo A
3.91
4.35
22.2
Robust STDev
0.263
0.0516
0.280
Median
4.01
4.36
22.1
STDev from MAD
0.237
0.0403
0.239
Arithmetic mean
3.84
4.38
22.7
STDev
0.365
0.321
0.950
CV or Variability
6.7%
1.2%
1.3%
When fewer than 20 results were considered for statistical treatment of all or a sub-sample of
results, the accuracy of statistical data may be questionable.
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
58
Distribution
Urine Zinc (µmol/L)
Centre de toxicologie du Québec/INSPQ - External quality assessment schemes
59
Interlaboratory Comparison Program
for Metals in Biological Matrices
ASSIGNED VALUES
ROUND:
2014-03
SHIPPED ON: 2014-04-22
DEADLINE: 2014-05-30
MATRIX
Blood
Serum
Urine
ANALYTE
UNIT
PTM
ASSIGNED
VALUE
PTM
ASSIGNED
VALUE
PTM
ASSIGNED
VALUE
Cadmium
nmol/L
PC-B-C1407
84.4
PC-B-C1408
15.4
PC-B-C1409
32.4
Lead
µmol/L
PC-B-L1407
0.154
PC-B-L1408
0.433
PC-B-L1409
1.75
Mercury
nmol/L
PC-B-M1407
171
PC-B-M1408
12.2
PC-B-M1409
81.2
Aluminium
µmol/L
PC-S-A1407
2.06
PC-S-A1408
8.38
PC-S-A1409
1.00
Copper
µmol/L
PC-S-E1407
9.36
PC-S-E1408
13.3
PC-S-E1409
27.7
Manganese
nmol/L
PC-S-G1407
38.8
PC-S-G1408
60.1
PC-S-G1409
87.1
Selenium
µmol/L
PC-S-E1407
0.921
PC-S-E1408
1.63
PC-S-E1409
2.70
Zinc
µmol/L
PC-S-E1407
10.7
PC-S-E1408
16.4
PC-S-E1409
23.6
Cadmium
nmol/L
PC-U-D1407
27.5
PC-U-D1408
82.7
PC-U-D1409
10.8
Chromium
nmol/L
PC-U-B1407
307
PC-U-B1408
27.9
PC-U-B1409
147
Copper
µmol/L
PC-U-R1407
0.176
PC-U-R1408
0.684
PC-U-R1409
11.3
Fluoride
µmol/L
PC-U-F1407
208
PC-U-F1408
91.7
PC-U-F1409
1180
Inorganic arsenic
µmol/L
PC-U-S1407
0.280
PC-U-S1408
1.34
PC-U-S1409
6.27
Iodide
µmol/L
PC-U-I1407
1.46
PC-U-I1408
0.882
PC-U-I1409
2.63
Lead
µmol/L
PC-U-P1407
0.546
PC-U-P1408
0.260
PC-U-P1409
4.29
Mercury
nmol/L
PC-U-H1407
67.1
PC-U-H1408
389
PC-U-H1409
1260
Selenium
µmol/L
PC-U-N1407
2.99
PC-U-N1408
1.19
PC-U-N1409
1.78
Total arsenic
µmol/L
PC-U-S1407
0.372
PC-U-S1408
1.44
PC-U-S1409
6.51
Zinc
µmol/L
PC-U-R1407
4.27
PC-U-R1408
4.89
PC-U-R1409
24.1
Centre de toxicologie/INSPQ
945, Ave Wolfe
Quebec, QC
Canada, G1V 5B3
Phone: (418) 650-5115 Ext. 5254
Fax : (418) 654-2148
E-mail : [email protected]
http://www.inspq.qc.a/ctq
60
Interlaboratory Comparison Program for Metals in
Biological Matrices (PCI)
GROUPING OF ANALYTICAL METHODS
FOR STATISTICS
METHODS GROUPING
CODE
METHODS GROUPING
METHODS INCLUDED
METHODS CODE
Atomic fluorescence
AFS
AFS
Atomic fluorescence
Cold vapor-atomic
fluorescence
CV-AFS
COLOR
Colorimetry
Colorimetry
Color
CV
Cold vapor
Cold vapor
CV
Cold vapor-AAS
CV-AAS
ESA
ESA Lead Care TM
system
ESA Lead Care TM
system
ESA Lead
FAAS
Flame-AAS
Flame-AAS
FAAS
FSE
Fluoride specific
electrode
Fluoride specific
electrode
FSE
GA-AAS
Gold amalgamationAAS
Gold amalgamationAAS
AA-Gold A
Deuterium and otherGraphite furnace-AAS
D2-GFAAS
Zeeman-Graphite
furnace-AAS
Z-GFAAS
GFAAS
Graphite furnace-AAS
HG-AAS
Hydride generationAAS
Hydride generationAAS
HG-AAS
HR-ICP-MS
ICP-MS (high
resolution)
ICP-MS (high
resolution)
HR-ICP-MS
ICP-MS
ICP-MS
ICP-MS (isotopic
dilution)
ID-ICP-MS
ICP-MS (laser
ablation/furnace)
ICP-MS (LA)
ICP-MS
ICP-MS
ICP-MS (C/R)
ICP-MS
(collision/reaction
cell)
ICP-MS
(collision/reaction
cell)
ICP-MS(C/R)
ICP-OES
ICP-OES (optical
emission)
ICP-OES (optical
emission)
ICP-OES
POL
Polarography
Polarography
Polaro
Centre de toxicologie/INSPQ
945, Ave Wolfe
Quebec, QC
Canada, G1V 5B3
Phone: (418) 650-5115 Ext. 5254
Fax : (418) 654-2148
E-mail : [email protected]
http://www.inspq.qc.a/ctq
61
Interlaboratory Comparison Program
for Metals in Biological Matrices (PCI)
1. Kolmogorov-Smirnov (Lilliefors) test
The Kolmogorov-Smirnov (Lilliefors) statistical test is a tool used to evaluate the normality
of a distribution of results. The test can be performed with N ≥ 4.
The power of the test increases rapidly with the number of observations. For≥ N30, the
test will be sensitive to account for small deviations from normality even with the presence
of only one outlier.
For a small sample size (N ≤ 10), the hypothesis that the observations follow a normal
distribution will generally be accepted. However, if normality is rejected for N≤ 10, this
indicates that the observations are far from following a normal distribution and that one or
more observations are most likely outliers.
When the normality hypothesis is rejected, the use of robust methods for the determination
of the AV by consensus such as the Algorithm A allows to obtain a better estimation of the
AV. Outliers are retained except if their deviation from the other observations can be
clearly explained as indicated in section 1.1.
The normality hypothesis is rejected when the statistical value is too weak according to the
Kolmogorov-Smirnov (Lilliefors) critical value table. The result of the normality of the
distribution of each set of observations is provided in the report whether the test is
“Accepted” or “Rejected” under the column labeled “KS (Lilliefors)”.
*** END OF REPORT ***
Centre de toxicologie/INSPQ
945, Wolfe Avenue
Quebec, QC
Canada, G1V 5B3
Phone: (418) 650-5115, ext. 5254
Fax: (418) 654-2148
E-mail: [email protected]
http://www.inspq.qc.ca/ctq
62
| File Type | application/pdf |
| Author | David Bisson |
| File Modified | 2014-06-20 |
| File Created | 2014-06-20 |