Overview of Changes for NASS

Overview of Changes for NASS Data Collection System

Added variables (n=25):

Sex of patient

Intended duration of oocyte banking

Intended duration of embryo banking

Months/years attempting pregnancy

Number of prior ectopic pregnancies

Number of prior ART cycles resulting in pregnancy

Anti-Mullerian Hormone (AMH) level (ng/mL)

Date of AMH level

Sperm source date of birth

Sperm source ethnicity

Sperm source race

Letrozole dosage

Other oral medication dosage

Medications with LH/HCG activity

Complications of stimulation or retrieval

Total 2PN

Pre-implantation genetic diagnosis or screening technique

Transfer attempted

Reason transfer not attempted

Endometrial Thickness

Quality of embryo (fresh embryo transfers)

Quality of embryo (thawed embryo transfers)

Method of delivery

Monochorionicity

Neonatal death (liveborn infants)

Dropped variables (n=16):

Lab Upper Normal Limit for that FSH level

Lab upper normal FSH unknown

FSH Unknown

Patient Maximum Estradiol Level

Lab Upper Normal Limit for that Estradiol Level

Number of Fresh Embryos Transferred to Fallopian Tubes

Number of Thawed Embryos Transferred to Fallopian Tubes

Surgical Sterilization—Patient or Partner

Ultrasound Performed

Patient smoked 100 cigarettes during life

Number smoked per day

Donor medicated to stimulate follicular development

Donor medications containing clomiphene

Donor clomiphene dosage

Donor medications containing FSH

Donor GnRH protocol

Modified variables (n=47):

Patient Optional Identifiers

Cycle start date

Patient US Resident

Patient State of Residence

Patient city of residence

Patient Zip Code of residence

Intended cycle type

Embryo or oocyte banking type

Intended embryo source

Intended oocyte source and state

Intended sperm source and state

Intended pregnancy carrier type

Actual cycle type

Actual embryo source

Actual oocyte source and state

Reason for ART

History of cigarette smoking

Gravidity

Number of prior stimulations for ART

Maximum Follicle Stimulating Hormone (FSH) Level

Oocyte source date of birth

Oocyte source ethnicity

Oocyte source race

Actual pregnancy carrier type

Pregnancy carrier date of birth

Pregnancy carrier ethnicity

Pregnancy carrier race

Actual sperm source

Oral medications given

FSH dosage (short acting)

FSH dosage (long acting)

GnRH Protocol

Reason for Cancel

Use of retrieved oocytes

Complication type

Hospitalization for Complication

Sperm collection method

Use of intracytoplasmic sperm Injection

In vitro maturation used

PGD/PGS reason

Use of assisted hatching

Study type

Elective single embryo transfer (frozen transfers)

Number of Oocytes or embryos transferred to fallopian tubes

Maximum Number of Fetal Hearts Observed on Ultrasound

Ultrasound Date

Birth defects diagnosed for each live-born and stillborn infant

Unchanged variables (n=33):

NASS Patient ID

Patient Date of Birth

Patient Country of Residence (if not US)

Female Patient Height

Female Patient Weight

Number of prior preterm births

Number of prior spontaneous abortions

Number of prior frozen ART cycles

Clomiphene dosage

Medications containing FSH

Cycle cancelled before retrieval

Date of Cancellation

Date of Oocyte Retrieval (fresh/thawed)

Number of Patient Oocytes Retrieved

Number of Donor Oocytes Retrieved

Number of Fresh Oocytes Cryopreserved

PGD or PGS performed on embryos

Number of Fresh Embryos Transferred to Uterus

Elective single embryo transfer (fresh transfers)

Number of Fresh Embryos Cryopreserved

Number of Thawed Embryos Transferred to Uterus

Number of Thawed Embryos Cryopreserved (re-frozen)

Outcome of treatment

Outcome of pregnancy

Date of pregnancy outcome

Source of information on pregnancy outcome

Number of infants born

Birth outcome for each Infant

Gender for each liveborn or stillborn infant

Birth weight for each live-born and stillborn infant

Number of prior full-term births

Medications given to stimulate follicular development

Transfer Date