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Emergency Epidemic Investigations

ICR 201610-0920-005 · OMB 0920-1141 · Object 68716701.

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Emergency Epidemic Investigations
CDC User
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2016-10-14
2026-10-10
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Chart Abstraction Questionnaire for the Investigation of Severe Neurologic Illness
in Relation to Arboviral Infections

















	
Chart Abstractor:	____________________________	Abstraction Date: __ __ /__ __ /________		
MRN:			____________________________                                        MM     DD     YYYY
Hospital:                         ____________________________	
    1. First name: _______________________________  	Middle name: ______________________________
    2. Paternal name: ____________________________ 	Maternal name: _____________________________
    3. Age (years): ______________________________  	Date of birth:  __ __ /__  __ /________
   								           MM     DD     YYYY
    4. Sex: □ Male   		□ Female	
    5. Patient address: ___________________________________________________________________________
    6. Patient zip code: ____   ____   ____  ____   ____  
    7. Patient phone number: ______________________
    8. Date of admission:  __ __ /__  __ /________		Date first sought care: __ __ /__  __ /________
   		       MM     DD     YYYY                                                              MM     DD     YYYY

Date of discharge/death: __ __ /__ __ /________
   		               MM     DD     YYYY				               
    9. Discharged to: 
□ Home (with outpatient PT: Yes / No)       □ Rehab/skilled nursing facility                              □ Hospice    
□ Transferred (specify hospital) ________________        □ Died      □ Other (specify) _______________     
    10. Health insurance: □ Reforma/SSS   □ Private   □ Veteran’s   □ None   □ Other (specify) _______________    

    11. How long from onset until hospital admission? __________minutes/hours/days/weeks
           		
    12. What were the initial neurologic symptoms within the three days prior to illness onset? (check all that apply, signs from PE, symptoms from HPI)
	□ Leg weakness		□ Arm weakness				□ Diplopia/Ophthalmoplegia
	□ Leg numbness/paresthesias	□ Arm numbness/paresthesias			□ Face numbness/paresthesias
	□ SOB / respiratory distress	□ Gait imbalance (not weakness)/ataxia	□ Hand clumsiness/ataxia
 	□ Hyporeflexia/areflexia	□ Dysarthria 		□ Dysphagia           	□ Dysautonomia
	□ Face weakness (circle: unilateral or bilateral)

    13. What neurologic symptoms occurred AT ANY TIME during the neuro illness? (check all that apply, signs from PE, symptoms from HPI)
	□ Leg weakness		□ Arm weakness				□ Diplopia/Ophthalmoplegia
	□ Leg numbness/paresthesias	□ Arm numbness/paresthesias			□ Face numbness/paresthesias
	□ SOB / respiratory distress	□ Gait imbalance (not weakness)/ataxia	□ Hand clumsiness/ataxia
 	□ Hyporeflexia/areflexia	□ Dysarthria 	□ Dysphagia           		□ Dysautonomia
	□ Face weakness (circle: unilateral or bilateral
    14. Were motor deficits present? □ Yes	□ No 	□ Unknown If so, describe:__________________________

    15. Date of maximum/worst neuro symptoms:  __ __ /__ __ /________
   		                                                   MM     DD     YYYY                                                              

    16. At the worst point during this neuro illness, check all that apply for the patient:
	□ Unable to walk without assistance	□ Unable to walk at all		□ Admitted to the hospital		□ Admitted to the ICU/CCU		□ Intubated			□ Coma
    17. Was there documented hyporeflexia/areflexia?    	□ Yes 		□ No  		□ Unknown

    18. Was there documentation of upper motor neuron signs?
□ Hyperreflexia	□ Increased tone/spasticity	□ Babinski/Hoffman		□ Sustained clonus

    19. Was there any sensory level documented? 		□ Yes 		□ No  		□ Unknown

    20. Did they receive any targeted treatment (IVIg/steroids/plasma exchange) for this neuro illness?   
	IVIg 			□ Yes   □ No    □ Unknown		Start date 	__ __ /__ __ /________
                                                                                                                       	MM     DD     YYYY
Plasma exchange 	□ Yes   □ No    □ Unknown		Start date 	__ __ /__ __ /________
                                                                                                                       	MM     DD     YYYY
	Steroids 		□ Yes   □ No    □ Unknown		Start date 	__ __ /__ __ /________
                                                                                                                       	MM     DD     YYYY
Mechanical ventilation 	□ Yes   □ No    □ Unknown		Start date 	__ __ /__ __ /________
                                                                                                                      	MM     DD     YYYY 
	Acyclovir	 	□ Yes   □ No    □ Unknown		Start date 	__ __ /__ __ /________
                                                                                                                      	MM     DD     YYYY
	Other  			□ Yes   □ No    □ Unknown		Start date 	__ __ /__ __ /________
                                                                                                                       	MM     DD     YYYY
    21. Did the patient receive blood transfusion/blood products (other than IVIg)? 
□ Yes   □ No    □ Unknown	If so, which: ______________   Start date 	__ __ /__ __ /________
                                                                                             			              MM     DD     YYYY


    22. If any blood was taken for this neurologic illness, please fill out the following for the INITIAL blood draw:
Date __ __ /__  __ /_______	WBC ____ 	HgB____	Plts _____	Na ____	K____
          MM     DD     YYYY			 
BUN ____	Cr ______	Glucose____	TBili____	AST ____	ALT____	AlkPhos ___

    23. Was a lumbar puncture (LP) done?		□ Yes	 	□ No		□ Unknown
LP date ___/____/____  RBCS _______   WBCS ______   Protein (mg/dL)______    Glucose (mg/dL) _______
          MM   DD  YYYY
Differential________________________IgG index______ Oligoclonal bands______ IgG synthesis___________
Opening pressure ___________________

Was an additional lumbar puncture (LP) done?	□ Yes	 	□ No		□ Unknown
LP date ___/____/____  RBCS _______   WBCS ______   Protein (mg/dL)______    Glucose (mg/dL) _______
          MM   DD  YYYY
Differential________________________IgG index______ Oligoclonal bands______ IgG synthesis___________
Opening pressure ___________________

    24. Were any of the following pathogens tested for? If so, what was the result? (including specimen and type of test)
    a. Campylobacter jejuni			□ Yes	 □ No     Result: _____________________________________
    b. Mycoplasma pneumoniae		□ Yes	 □ No     Result: _____________________________________
    c. Haemophilus influenzae			□ Yes	 □ No     Result: _____________________________________
    d. Salmonella spp.				□ Yes	 □ No     Result: _____________________________________
    e. Cytomegalovirus (CMV)		□ Yes	 □ No     Result: _____________________________________
    f. Epstein-Barr virus (EBV)		□ Yes	 □ No     Result: _____________________________________
    g. Varicella-zoster virus (VZV)		□ Yes	 □ No     Result: _____________________________________
    h. Human immunodeficiency virus (HIV)	□ Yes	 □ No     Result: _____________________________________
    i. Herpes simplex virus (HSV)		□ Yes	 □ No     Result: _____________________________________
    j. Enterovirus / Rhinovirus		□ Yes	 □ No     Result: _____________________________________
    k. Arboviruses				□ Yes	 □ No     Result: _____________________________________
    l. Cryptococcus				□ Yes	 □ No     Result: _____________________________________
    m. Toxoplasmosis				□ Yes	 □ No     Result: _____________________________________
    n. Other: __________________________	□ Yes	 □ No     Result: _____________________________________
    o. Other: __________________________	□ Yes	 □ No     Result: _____________________________________
    p. Other: __________________________	□ Yes	 □ No     Result: _____________________________________
    q. Other: __________________________	□ Yes	 □ No     Result: _____________________________________
    r. Other: __________________________	□ Yes	 □ No     Result: _____________________________________
    s. Other: __________________________	□ Yes	 □ No     Result: _____________________________________


    25. Was neuro imaging done? If so, what was the result? (Transcribe the impression)
□ Yes	 □ No   Result: _______________________________________________________________________
__________________________________________				Date __ __ /__ __ /________
                                                                                                                                             MM     DD     YYYY   
    26. Were electro-diagnostics done (e.g. EMG)? If so, what were the results? (Transcribe the impression)
□ Yes	 □ No   Result: _______________________________________________________________________
__________________________________________				Date __ __ /__ __ /________
                                                                                                                                             MM     DD     YYYY   
    27. What was the GBS Brighton level?		1	2	3	4            5


    28. a.) In the 2 months prior to neuro onset date, did the individual experience an acute illness?     
□ Yes   	□No	   □ Unknown  	     

How long from prior acute illness onset until admission for neuro illness? _________ minutes/hours/days/weeks

    29. b.) What symptoms did they report having or what signs were noticed? (check all that apply)
□ Fevers		□ Chills		□ Nausea or Vomiting		□ Diarrhea		                                                  □ Muscle pains	□ Joint pains		□ Skin rash			□ Conjunctivitis
□ Headache		□ Pain behind eyes	□ Stiff neck			□ Confusion    □ Back pain
□ Abdominal pain	□ Coughing		□ Runny nose			□ Sore throat	□ Calf pain
c.) If any blood was taken for this acute illness, please fill out the following for the INITIAL blood draw:
Date __ __ /__  __ /________        	WBC ____ 	HgB____	Plts _____	Na ____	K____ 
         DD     MM      YYYY
BUN ____	Cr ______	Glucose____	TBili____	AST ____	ALT____	AlkPhos ___
d.) Were they hospitalized for this acute illness?				□ Yes     □ No     □ Unknown
e.) Did they receive any blood products / IVIg for this illness?		□ Yes     □ No     □ Unknown
What product?	_____________________		Date? 	__ __ /__ __ /________
                                                                                MM     DD     YYYY
g.) Did they receive plasmapheresis / plasma exchange for this illness?  	□ Yes     □ No     □ Unknown
			If yes, date? 	__ __ /__ __ /________
                                                                   MM     DD     YYYY   
    30. Is there a test result available for dengue from this medical visit? 	□  Yes     □ No     □ Unknown
    31. Is there a test result available for chikungunya from this medical visit? 	□  Yes     □ No     □ Unknown
    32. Is there a test result available for Zika from this medical visit? 		□  Yes     □ No     □ Unknown
    33. What medical conditions are listed in the admission history and physical (H&P)?
□ Hypertension	□ Diabetes	□ HIV		□ Syphilis	□ Autoimmune disorder____________
□ B12 deficiency 	□ Hemoglobinopathy 		□ Prior GBS	□ Cancer _______________________ 

    34. What conditions are listed in family history of H&P?
□ Autoimmune disorder (specify): ___________________	□ Cancer (specify): _____________________
□ Hemoglobinopathy (specify): _____________________	□ Neuro (specify): ______________________ 

    35. What social conditions are listed in admission H&P?
□ Alcohol use		□ Drug use		□ Tobacco		□ Other ________________________
    36. Did the patient receive a vaccine in the previous 6 months? 		□  Yes	       □ No        □ Unknown
If yes, vaccine: _________________			Date of vaccination: __ __ /__ __ /________
                                                                   					MM     DD     YYYY

    37. What other neurologic conditions were identified by the provider?
 □ ADEM   □ CIDP 	 □ Encephalitis   	    □ Encephalomyelitis	         □ Facial paralysis	
 □ Meningoencephalitis	 □ Myasthenia gravis     □ Myelitis	 	                     □ Myelopathy 	
 □ Multiple sclerosis (MS)  	 □ Neuropathy 	    □ Optic neuritis           	         □ Paresthesia		
 □ Papilledema		 □ Transverse myelitis   □ Sensory motor peripheral neuropathy 
 □ Stroke			□ Other: _________________________________________________________

    38. Additional signs or symptoms not already noted:
□
Agitation
□
Altered lacrimal gland secretion
□
Altered mental status
□
Altered salivary gland secretion
□
Aphasia
□
Confusion
□
Drooping corner of mouth
□
Eye pain
□
Eyebrow sagging
□
Fatigable chewing
□
Fever
□
Headache
□
Inability to close eye
□
Irritability
□
Lethargy
□
Lower extremity dysthesesia
□
Loss of taste anterior 2/3 of tongue
□
Memory loss
□
Nausea
□
Nasolabial fold disappearance
□
Nuchal rigidity
□
Nystagmus
□
Oculomotor deficits
□
Personality changes
□
Ptosis
□
Seizures
□
Sensory deficits:
□
Somnolence





______________________


□
Transient visual obscuration
□
Tremors
□
Upper extremity dysthesesia
□
Urinary retention
□
Vision loss
□
Vomiting
□
Other: _________________
□
Other: ___________________