PFAS Levels

P_Att02_PFASLevelsPease_vs_ExtrnlPopn 20180802.docx

Human Health Effects of Drinking Water Exposures to Per- and Polyfluoroalkyl Substances (PFAS) at Pease International Tradeport, Portsmouth, NH (The Pease Study)

PFAS Levels

OMB: 0923-0061

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Attachment 2. PFAS Serum Levels, Pease vs. External Populations

Attachment 2a. Pease serum PFAS levels in µg/L, by age groups, 2018

Population age, 2018


PFOS

PFOA

PFHxS

4 – 17 (N=379)

Mean

9.66

3.85

5.47


SD

6.01

2.14

4.62

Median

8.09

3.40

4.10

Geometric mean

7.98

3.29

3.75

Maximum

30.80

12.00

31.70

Top quartile

12.70

5.00

7.60

Top quintile

14.20

5.41

8.79






18 (n=1,190)

Mean

11.59

3.76

7.05


SD

9.63

2.74

8.75

Median

9.30

3.12

4.21

Geometric mean

8.82

3.02

4.26

Maximum

95.60

32.00

116.00

Top quartile

14.20

4.65

8.60

Top quintile

16.10

5.20

10.00






18, not a firefighter (n=1,092)

Mean

10.95

3.75

6.52


SD

8.32

2.78

7.44

Median

8.97

3.10

4.08

Geometric mean

8.53

2.99

4.04

Maximum

78.00

32.00

61.40

Top quartile

13.70

4.62

8.10

Top quintile

15.50

5.10

9.45






Firefighter (n=98)

Mean

18.70

3.93

12.95


SD

17.41

2.14

16.64

Median

11.75

3.40

8.14

Geometric mean

12.80

3.37

7.74

Maximum

95.60

12.10

116.00

Top quartile

23.10

5.26

14.70

Top quintile

28.64

5.90

17.46





Attachment 2b. Serum PFAS levels in µg/L, children aged <12 years, Pease vs. comparisons

PFAS

Pease Tradeport*

TX

CA

Median

Geometric Mean

95% CI

Maximum

Median

Maximum

Median

Geometric Mean

Maximum

PFOA

3.63

3.43

3.23 – 3.64

12.00

2.85

13.50

4.50

4.46

19.50

PFOS

8.27

8.11

7.59 – 8.67

30.80

4.10

93.90

6.15

6.28

26.70

PFHxS

4.24

3.83

3.48 – 4.22

31.70

1.20

31.20

1.25

1.30

9.80

PFNA

0.90

0.92

0.86 – 0.98

5.20

1.20

55.80

1.70

1.84

11.20

* Pease: N=366, aged <12 years; sampling occurred in 2015.

Texas (TX) reference group: N=300, age ≤12 years (Schecter et al 2012), sampling occurred in 2009.

California (CA) reference group: N=68, ages 2-8 years (Wu et al 2015), sampling occurred in 2007-2009.



Attachment 2c. Serum PFAS levels in µg/L, aged ≥12 years, Pease vs. NHANES

PFAS

Pease Tradeport*

NHANES 2013-2014

Median

Geometric Mean

95% CI

Max.

Median

Geometric Mean

95% CI

95th percentile

PFOA

3.10

2.99

2.87 – 3.11

32.00

2.07

1.94

1.76 – 2.14

5.57

PFOS

9.17

8.74

8.37 – 9.13

95.60

5.20

4.99

4.50 – 5.52

18.50

PFHxS

4.16

4.21

3.98 – 4.46

116.00

1.40

1.35

1.20 – 1.60

5.60

PFNA

0.70

0.68

0.65 – 0.70

4.90

0.70

0.68

0.61 – 0.72

2.00

* N=1,212 ages ≥12 years, sampled in 2015.

N=2,168 ages ≥12 years.


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