30-day FRN

Federal Register / Vol. 86, No. 174 / Monday, September 13, 2021 / Notices

lotter on DSK11XQN23PROD with NOTICES1

5. Chinese Patent Application
201880063656.4, filed September 17,
2018 (E–237–2017–1–CN–05);
6. European Patent Application
18782605.2, filed September 17, 2018
(E–237–2017–1–EP–06);
7. Israeli Patent Application 273516,
filed September 17, 2018 (E–237–2017–
1–IL–07);
8. Japanese Patent Application 2020–
517553, filed September 17, 2018 (E–
237–2017–1–JP–08);
9. Korean Patent Application 2020–
7012343, filed September 17, 2018 (E–
237–2017–1–KR–09);
10. Singapore Patent Application
11202002635R, filed September 17,
2018 (E–237–2017–1–SG–10);
11. United States Utility Patent
Application 16/650,696, filed
September 17, 2018 (E–237–2017–1–
US–11); and
12. Hong Kong Patent Application
62020021274.9, filed November 30,
2020 (E–237–2017–1–HK–12).
The patent rights in these inventions
have been assigned and/or exclusively
licensed to the government of the
United States of America.
The prospective exclusive license
territory may be worldwide and the
fields of use may be limited to the
following:
Fields of Use Applying to Intellectual
Property Group A
‘‘Development, manufacture, and
commercialization of allogeneic Natural
Killer T (NKT) cell therapy products
engineered via viral and non-viral means,
including CRISPR modification, to express T
cell receptors reactive to mutated P53, KRAS,
and EGFR within the context of multiple
HLAs, as claimed in the Licensed Patent
Rights, for the treatment of human cancers.
For the purposes of this license, NKT cells
are a subset of peripheral blood lymphocytes
specifically and intentionally isolated based
on unique characteristics of NKT cells
resulting in a manufactured clinical product
containing at least 50% NKT cells.’’
Fields of Use Applying to Intellectual
Property Group B
‘‘Development, manufacture, and
commercialization of allogeneic Natural
Killer T (NKT) cell therapy products
engineered via viral and non-viral means,
including CRISPR modification, to express T
cell receptors reactive to mutated P53,
isolated as claimed in the Licensed Patent
Rights, for the treatment of human cancers.
For the purposes of this license, NKT cells
are a subset of peripheral blood lymphocytes
specifically and intentionally isolated based
on unique characteristics of NKT cells
resulting in a manufactured clinical product
containing at least 50% NKT cells.’’

Intellectual Property Group A
description is as follows:
E–237–2017–0, E–135–2019 and E–173–
2020 patent rights are primarily directed to

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isolated TCRs reactive to mutated tumor
protein 53 (TP53 or P53), within the context
of several HLAs. P53 is the archetypal tumor
suppressor gene and the most frequently
mutated gene in cancer. Contemporary
estimates suggest that >50% of all tumors
carry mutations in P53. Because of its
prevalence in cancer and its restricted
expression to precancerous and cancerous
cells, this antigen may be targeted on mutant
P53-expressing tumors with minimal normal
tissue toxicity.
E–165–2020, E–172–2020, E–189–2020 and
E–190–2020 patent rights are primarily
directed to isolated TCRs reactive to mutated
Kirsten rat sarcoma viral oncogene homolog
(KRAS), within the context of several human
leukocyte antigens (HLAs). Mutated KRAS,
which plays a well-defined driver role in
oncogenesis, is expressed by a variety of
human cancers, including: Pancreatic, lung,
endometrial, ovarian and prostate. Due to its
restricted expression in precancerous and
cancerous cells, this antigen may be targeted
on mutant KRAS-expressing tumors with
minimal normal tissue toxicity.
E–098–2018 patent rights are primarily
directed to isolated TCRs reactive to mutated
epidermal growth factor receptor (EGFR),
within the context of HLA DPA1*02:01
DPB1*01:01. EGFR is a transmembrane
protein involved in cell growth and
proliferation signaling. Mutations in the gene
encoding EGFR can lead to its
overexpression, causing several types of
cancer (e.g., non-small cell lung cancer
(NSCLC)). Because of its prevalence in
certain cancers and its restricted expression
to precancerous and cancerous tissues, this
antigen may be targeted on mutant EGFRexpressing tumors with minimal normal
tissue toxicity.

Intellectual Property Group B
description is as follows:
E–237–2017–1 patent rights are primarily
directed to methods of rapidly isolating T
cells which are reactive to mutated P53
antigens. Briefly, pools of 25-mer peptides
covering all known P53 ‘‘hotspot’’ mutations
have been generated. These peptides may be
pulsed into antigen presenting cells which
are subsequently co-cultured with isolated T
cells. Reactive T cells are then purified and
may be used as source material for the further
isolation of mutant P53-targeting TCRs.

This notice is made in accordance
with 35 U.S.C. 209 and 37 CFR part 404.
The prospective exclusive license will
be royalty bearing, and the prospective
exclusive license may be granted unless
within fifteen (15) days from the date of
this published notice, the National
Cancer Institute receives written
evidence and argument that establishes
that the grant of the license would not
be consistent with the requirements of
35 U.S.C. 209 and 37 CFR part 404.
In response to this Notice, the public
may file comments or objections.
Comments and objections, other than
those in the form of a license
application, will not be treated

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confidentially, and may be made
publicly available.
License applications submitted in
response to this Notice will be
presumed to contain business
confidential information and any release
of information in these license
applications will be made only as
required and upon a request under the
Freedom of Information Act, 5 U.S.C.
552.
Dated: September 7, 2021.
Richard U. Rodriguez,
Associate Director, Technology Transfer
Center, National Cancer Institute.
[FR Doc. 2021–19604 Filed 9–10–21; 8:45 am]
BILLING CODE 4140–01–P

DEPARTMENT OF THE INTERIOR
Bureau of Land Management
[L14400000 PN0000 HQ350000 212; OMB
Control Number 1004–0012]

Agency Information Collection
Activities; Application for Land for
Recreation or Public Purposes
Bureau of Land Management,
Interior.
ACTION: Notice of information collection;
request for comment.
AGENCY:

In accordance with the
Paperwork Reduction Act of 1995
(PRA), the Bureau of Land Management
(BLM) proposes to renew an information
collection.
DATES: Interested persons are invited to
submit comments on or before October
13, 2021.
ADDRESSES: Written comments and
recommendations for this information
collection request (ICR) should be sent
within 30 days of publication of this
notice to www.reginfo.gov/public/do/
PRAMain. Find this particular
information collection by selecting
‘‘Currently under 30-day Review—Open
for Public Comments’’ or by using the
search function.
FOR FURTHER INFORMATION CONTACT: To
request additional information about
this ICR, contact Susie Greenhalgh by
email at [email protected], or by
telephone at 202–302–4288. Individuals
who are hearing or speech impaired
may call the Federal Relay Service at 1–
800–877–8339 for TTY assistance. You
may also view the ICR at http://
www.reginfo.gov/public/do/PRAMain.
SUPPLEMENTARY INFORMATION: In
accordance with the PRA and 5 CFR
1320.8(d)(1), we provide the general
public and other Federal agencies with
an opportunity to comment on new,
SUMMARY:

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lotter on DSK11XQN23PROD with NOTICES1

50900

Federal Register / Vol. 86, No. 174 / Monday, September 13, 2021 / Notices

proposed, revised, and continuing
collections of information. This helps us
assess the impact of our information
collection requirements and minimize
the public’s reporting burden. It also
helps the public understand our
information collection requirements and
provide the requested data in the
desired format.
A Federal Register notice with a 60day public comment period soliciting
comments on this collection of
information was published on May 4,
2021 (86 FR 23737). No comments were
received.
As part of our continuing effort to
reduce paperwork and respondent
burdens, we are again soliciting
comments from the public and other
Federal agencies on the proposed ICR
that is described below. We are
especially interested in public comment
addressing the following:
(1) Whether or not the collection of
information is necessary for the proper
performance of the functions of the
agency, including whether or not the
information will have practical utility;
(2) The accuracy of our estimate of the
burden for this collection of
information, including the validity of
the methodology and assumptions used;
(3) Ways to enhance the quality,
utility, and clarity of the information to
be collected; and
(4) How might the agency minimize
the burden of the collection of
information on those who are to
respond, including through the use of
appropriate automated, electronic,
mechanical, or other technological
collection techniques or other forms of
information technology, e.g., permitting
electronic submission of response.
Comments that you submit in
response to this notice are a matter of
public record. Before including your
address, phone number, email address,
or other personal identifying
information in your comment, you
should be aware that your entire
comment—including your personal
identifying information—may be made
publicly available at any time. While
you can ask us in your comment to
withhold your personal identifying
information from public review, we
cannot guarantee that we will be able to
do so.
Abstract: The BLM uses the
information collection to decide
whether or not to lease or sell certain
public lands to applicants under the
Recreation and Public Purposes Act, 43
U.S.C. 869 to 869–4. OMB Control
Number 1004–0012 is scheduled to
expire on October 31, 2021. This request
is for OMB to renew this OMB Control

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Number for an additional three (3)
years.
Title of Collection: Application for
Land for Recreation or Public Purposes
(43 CFR 2740 and 2912).
OMB Control Number: 1004–0012.
Form Number: 2740–01.
Type of Review: Extension of a
currently approved collection.
Respondents/Affected Public: State,
Territory, County, and Local
governments; nonprofit corporations;
and nonprofit associations.
Total Estimated Number of Annual
Respondents: 23.
Total Estimated Number of Annual
Responses: 23.
Estimated Completion Time per
Response: 40 hours.
Total Estimated Number of Annual
Burden Hours: 920.
Respondent’s Obligation: Required to
obtain or retain a benefit.
Frequency of Collection: On occasion.
Total Estimated Annual Non-hour
Burden Cost: $2,300.
An agency may not conduct or
sponsor and, notwithstanding any other
provision of law, a person is not
required to respond to a collection of
information unless it displays a
currently valid OMB control number.
The authority for this action is the
Paperwork Reduction Act of 1995 (44
U.S.C. 3501 et seq.).
Darrin King,
Information Collection Clearance Officer.
[FR Doc. 2021–19624 Filed 9–10–21; 8:45 am]
BILLING CODE 4310–84–P

DEPARTMENT OF THE INTERIOR
National Park Service
[NPS–WASO–NAGPRA–NPS0032516;
PPWOCRADN0–PCU00RP14.R50000]

Notice of Inventory Completion: Illinois
State Museum, Springfield, IL
National Park Service, Interior.
Notice.

AGENCY:
ACTION:

The Illinois State Museum
has completed an inventory of human
remains and associated funerary objects,
in consultation with the appropriate
Indian Tribes or Native Hawaiian
organizations, and has determined that
there is a cultural affiliation between the
human remains and associated funerary
objects and present-day Indian Tribes or
Native Hawaiian organizations. Lineal
descendants or representatives of any
Indian Tribe or Native Hawaiian
organization not identified in this notice
that wish to request transfer of control
of these human remains and associated

SUMMARY:

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funerary objects should submit a written
request to the Illinois State Museum. If
no additional requestors come forward,
transfer of control of the human remains
and associated funerary objects to the
lineal descendants, Indian Tribes, or
Native Hawaiian organizations stated in
this notice may proceed.
DATES: Lineal descendants or
representatives of any Indian Tribe or
Native Hawaiian organization not
identified in this notice that wish to
request transfer of control of these
human remains and associated funerary
objects should submit a written request
with information in support of the
request to the Illinois State Museum at
the address in this notice by October 13,
2021.
FOR FURTHER INFORMATION CONTACT: Dr.
Brooke Morgan, Illinois State Museum
Research & Collections Center, 1011
East Ash Street, Springfield, IL 62703,
telephone (217) 785–8930, email
[email protected].
SUPPLEMENTARY INFORMATION: Notice is
here given in accordance with the
Native American Graves Protection and
Repatriation Act (NAGPRA), 25 U.S.C.
3003, of the completion of an inventory
of human remains and associated
funerary objects under the control of the
Illinois State Museum, Springfield, IL.
The human remains and associated
funerary objects were removed from
Grundy County, IL.
This notice is published as part of the
National Park Service’s administrative
responsibilities under NAGPRA, 25
U.S.C. 3003(d)(3). The determinations in
this notice are the sole responsibility of
the museum, institution, or Federal
agency that has control of the Native
American human remains and
associated funerary objects. The
National Park Service is not responsible
for the determinations in this notice.
Consultation
A detailed assessment of the human
remains was made by the Illinois State
Museum professional staff in
consultation with representatives of the
Forest County Potawatomi Community,
Wisconsin; Nottawaseppi Huron Band
of the Potawatomi, Michigan
[previously listed as Huron Potawatomi,
Inc.]; Peoria Tribe of Indians of
Oklahoma; and the Winnebago Tribe of
Nebraska. In addition, the Citizen
Potawatomi Nation, Oklahoma;
Hannahville Indian Community,
Michigan; Ho-Chunk Nation of
Wisconsin; Kickapoo Traditional Tribe
of Texas; Kickapoo Tribe of Indians of
the Kickapoo Reservation in Kansas;
Kickapoo Tribe of Oklahoma; Match-ebe-nash-she-wish Band of Pottawatomi

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