Lab Assessments 2019-20

Attachment 6b
Laboratory Assessments
2019-20 and earlier

NHANES Laboratory Assessments
Laboratory Analytes by Age Group
Contract and CDC Sexually Transmitted Infection (STI) Laboratories
Test Name
Household Collections
Fluoride (Ages 0-19 years old)
Iodine
Ages 1-2
Complete Blood Count
Congenital Cytomegalovirus (CMV)
C-reactive Protein (CRP)
Hepatitis B Surface Antibody (Anti-HBs) (2 years and older)
Ages 3-5
Albumin/Creatinine
Complete Blood Count
Congenital Cytomegalovirus (CMV)
C-reactive Protein (CRP)
Hepatitis B Surface Antibody (Anti-HBs)
Thyroid Profile
Urine Flow Rate
Ages 6-11
Albumin/Creatinine
Cholesterol (Total)/ High Density Lipoprotein Cholesterol (HDL)
Complete Blood Count
C-reactive Protein (CRP)
Hepatitis Profile2
Thyroid Profile
Tuberculosis (Mycobacterium tuberculosis ) Infection
Urine flow rate
Ages 12-19
Albumin/Creatinine
Biochemistry Profile1
Chlamydia trachomatis (14-19 years)
Cholesterol (Total)/ High Density Lipoprotein Cholesterol (HDL)
Complete Blood Count
C-reactive Protein (CRP)
Glucose, fasting
Glycohemoglobin
Hepatitis Profile2
Herpes Simplex Virus (HSV) (14-19 years)
Human Immunodeficiency Virus Antibody (18-19 years)
Human Papilloma Virus (Females and Males 14-19 years)
Human Papilloma Virus (14-19 years)
Insulin

Page 1 of 18

Sample

Matrix

Full
Full

Water
Salt

Full
Full
Full
Full

Whole blood
Serum
Serum
Serum

Full
Full
Full
Full
Full
Full
Full

Urine
Whole blood
Serum
Serum
Serum
Serum
Urine

Full
Full
Full
Full
Full
One-third
Full
Full

Urine
Serum
Whole blood
Serum
Serum
Serum
Whole blood
Urine

Full
Full
Full
Full
Full
Full
One-half
Full
Full
Full
Full
Full
Full
One-half

Urine
Serum
Urine
Serum
Whole blood
Serum
Plasma (Na2F)
Whole blood
Serum
Serum
Serum
Swab
Oral Rinse
Serum

Test Name
Serum Iron (Frozen)
Thyroid Profile
Transferrin Receptor (females)
Triglycerides/Low Density Lipoprotein Cholesterol
Trichomonas vaginalis (14-19 years)
Tuberculosis (Mycobacterium tuberculosis ) Infection
Unsaturated Iron-Binding Capacity (UIBC)
Urine flow rate
Ages 20 and older
Albumin/Creatinine
1

Biochemistry Profile
Chlamydia trachomatis (20-39 years)
Cholesterol (Total)/ High Density Lipoprotein Cholesterol (HDL)
Complete Blood Count
C-reactive Protein (CRP)
Glucose, fasting
Glycohemoglobin
Hepatitis Profile2
Herpes Simplex Virus (HSV) (20-49 years)
Human Immunodeficiency Virus antibody (20-59 years)
Human Papilloma Virus (20-59 years)
Human Papilloma Virus (Females and Males 20-59 years)
Human Papilloma Virus (20-69 years)
Insulin
Serum Iron (Frozen)
Thyroid Profile
Triglycerides/Low Density Lipoprotein Cholesterol
Trichomonas vaginalis (20-59 years)
Tuberculosis (Mycobacterium tuberculosis ) Infection
Unsaturated Iron-Binding Capacity (UIBC)
Urine flow rate
1

Biochemistry Profile
Albumin
Alkaline phosphatase
Aspartate aminotransferase (AST)
Alanine aminotransferase (ALT)
Blood urea nitrogen (BUN)
Bicarbonate (HCO3)
Total calcium
Total cholesterol
Chloride
CPK
Creatinine
Globulin

Page 2 of 18

Sample
Full
One-Third
Full
One-half
Full
Full
Full
Full

Matrix
Serum
Serum
Serum
Serum
Urine
Whole blood
Serum
Serum

Full
Full
Full
Full
Full
Full
One-half
Full
Full
Full
Full
Full
Full
Full
One-half
Full
One-Third
One-half
Full
Full
Full
Full

Urine
Serum
Urine
Serum
Whole blood
Serum
Plasma (Na2F)
Whole blood
Serum
Serum
Serum
Serum
Swab
Oral Rinse
Serum
Serum
Serum
Serum
Urine
Whole blood
Serum
Urine

Glucose
v-glutamyltransferase (GGT)
Iron
Potassium
Lactate dehydrogenase (LDH)
Sodium
Osmolality
Phosphorus
Total Bilirubin
Total protein
Triglycerides
Uric acid
2

Hepatitis Profile
Hepatitis A antibody (Anti-HAV)
Hepatitis B Core antibody (Anti-HBc)
Hepatitis B Surface Antibody (Anti-HBs)
Hepatitis B Surface Antigen (HbsAg)
Hepatitis C Antibody (Anti-HCV)
Hepatitis C HCV genotype
Hepatitis C Ribonucleic Acid (HCV-RNA)
Hepatitis D antibody (anti-HDV)
Hepatitis E antibody (anti-HEV)

Page 3 of 18

Attachment 5 – NHANES Laboratory Assessments
Attachment 5b - Laboratory Analytes by Survey Year
National Centers for Environmental Health (NCEH) - Division of Laboratory Services (DLS)
This list of chemicals represents those chemicals currently or planned as biomonitoring measurements by CDC. A blank cell indicates that the analyte
will not be measured or reported in that NHANES cycle. WD=results were withdrawn d=cycled out (not measured)

Chemical / Metabolite Name

Matrix

Lab

Acetaldehyde

serum

Acrolein

09-10

11-12

13-14

15-16

17-18

19-20

Branch

Lab Contact

4

WD

WD

WD

d

TVB

serum

4

WD

WD

WD

d

TVB

Benzaldehyde

serum

4

●

WD

WD

d

TVB

Butyraldehyde (butanal)

serum

4

●

WD

WD

d

TVB

Crotonaldehyde

serum

4

●

WD

WD

d

TVB

Decanal

serum

4

●

WD

WD

d

TVB

Furaldehyde

serum

4

●

WD

WD

d

TVB

Heptanal

serum

4

●

WD

WD

d

TVB

n-Hexanal

serum

4

●

WD

WD

d

TVB

Isobutyraldehyde

serum

4

WD

WD

d

TVB

Isovaleraldehyde (isopentaldehyde)

serum

4

●

WD

WD

d

TVB

Nonanal

serum

4

●

WD

WD

d

TVB

Octanal

serum

4

●

WD

WD

d

TVB

o-Tolualdehyde

serum

4

●

WD

WD

d

TVB

Pentanal

serum

4

●

WD

WD

d

TVB

Propionaldehyde (propanol)

serum

4

●

WD

WD

d

TVB

trans -Hexanal

serum

4

WD

d

TVB

trans- Octenal

serum

4

WD

d

TVB

trans -Nonenal

serum

4

WD

d

TVB

●

●

TVB

Chambers

TVB

Chambers

TVB

Chambers

TVB

Chambers

TVB

Chambers

TVB

Chambers

TVB

Chambers

TVB

Chambers

Aldehydes
Silva/
DeJesus
Silva/
DeJesus
Silva/
DeJesus
Silva/
DeJesus
Silva/
DeJesus
Silva/
DeJesus
Silva/
DeJesus
Silva/
DeJesus
Silva/
DeJesus
Silva/
DeJesus
Silva/
DeJesus
Silva/
DeJesus
Silva/
DeJesus
Silva/
DeJesus
Silva/
DeJesus
Silva/
DeJesus
Silva/
DeJesus
Silva/
DeJesus
Silva/
DeJesus

Disinfection By-Products - Volatile Organic Compounds (VOCs) - Trihalomethanes & MTBE
Bromodichloromethane

whole blood

4

●

●

Bromodichloromethane

water

4

●

d

Dibromochloromethane (Chlorodibromomethane)

whole blood

4

●

●

Dibromochloromethane (Chlorodibromomethane)

water

4

●

d

Tribromomethane (Bromoform)

whole blood

4

●

●

Tribromomethane (Bromoform)

water

4

●

d

Trichloromethane (Chloroform)

whole blood

4

●

●

Trichloromethane (Chloroform)

water

4

●

d

Page 4 of 18

●

●

●

●

●

●

●

●

●

●

●

●

●

●

Chemical / Metabolite Name

Matrix

Lab

09-10

11-12

Branch

Lab Contact

water

4

●

d

TVB

Chambers

Benzene

whole blood

4

●

●

●

●

●

●

TVB

DeJesus

Chlorobenzene

whole blood

4

●

●

●

●

●

●

TVB

DeJesus

1,2-Dichlorobenzene

whole blood

4

●

●

●

●

●

●

TVB

DeJesus

1,3-Dichlorobenzene

whole blood

4

●

●

●

●

●

●

TVB

DeJesus

1,4-Dichlorobenzene (Paradichlorobenzene)

whole blood

4

●

●

●

●

●

●

TVB

DeJesus

1,2-dibromo-3-chloropropane (DBCP)

whole blood

4

●

d

TVB

DeJesus

2,5-Dimethylfuran

whole blood

4

●

●

●

●

●

●

TVB

DeJesus

Ethylbenzene

whole blood

4

●

●

●

●

●

●

TVB

DeJesus

Dichloromethane (Methylene chloride)

whole blood

4

●

●

●

●

●

●

TVB

DeJesus

Trichloroethene (Trichloroethylene)

whole blood

4

●

●

●

●

●

●

TVB

DeJesus

Tetrachloroethene (Perchloroethylene)

whole blood

4

●

●

●

●

●

●

TVB

DeJesus

Dibromomethane

whole blood

4

●

●

d

TVB

DeJesus

1,1-Dichloroethane

whole blood

4

●

●

d

TVB

DeJesus

1,2-Dichloroethane (Ethylene dichloride)

whole blood

4

●

●

●

TVB

DeJesus

1,1-Dichloroethene (Vinylidene chloride)

whole blood

4

●

●

d

TVB

DeJesus

cis -1,2-Dichloroethene

whole blood

4

●

●

d

TVB

DeJesus

trans -1,2-Dichloroethene

whole blood

4

●

●

d

TVB

DeJesus

1,2-Dichloropropane

whole blood

4

●

●

d

TVB

DeJesus

1,1,1-Trichloroethane (Methyl chloroform)

whole blood

4

●

●

●

TVB

DeJesus

1,1,2-Trichloroethane

whole blood

4

●

●

d

TVB

DeJesus

1,1,2,2-Tetrachloroethane

whole blood

4

●

●

d

TVB

DeJesus

Tetrachloromethane (Carbon tetrachloride)

whole blood

4

●

●

●

TVB

DeJesus

Hexachloroethane

whole blood

4

●

●

d

TVB

DeJesus

Diethylether

whole blood

4

●

●

●

●

TVB

DeJesus

Isobutyronitrile

whole blood

4

WD

●

●

●

TVB

DeJesus

Methyl-tert -butyl ether (MTBE)

whole blood

4

●

●

●

●

●

●

TVB

DeJesus

Nitrobenzene

whole blood

4

●

●

●

●

●

●

TVB

DeJesus

Styrene

whole blood

4

●

WD

WD

WD

●

●

TVB

DeJesus

Toluene

whole blood

4

●

WD

●

●

●

●

TVB

DeJesus

m-/p -Xylene

whole blood

4

●

●

●

●

●

●

TVB

DeJesus

o -Xylene

whole blood

4

●

●

●

●

●

●

TVB

DeJesus

Isopropylbenzene (Cumene)

whole blood

4

●

●

●

●

●

●

TVB

DeJesus

1,2-Dibromoethane

whole blood

4

●

●

●

●

●

●

TVB

DeJesus

1,4-Dioxane

whole blood

4

●

●

●

●

WD

d

TVB

DeJesus

Furan

whole blood

4

●

●

●

●

●

●

TVB

DeJesus

n -Hexane

whole blood

4

●

●

●

●

●

●

TVB

DeJesus

Nitromethane

whole blood

4

●

●

d

TVB

DeJesus

1,1,1,2-Tetrachloroethane (VCE)

whole blood

4

●

●

●

TVB

DeJesus

MTBE

13-14

15-16

17-18

19-20

Volatile Organic Compounds (VOCs)

Page 5 of 18

●

●

●

●

●

●

●

●

●

●

●

●

Chemical / Metabolite Name

Matrix

Lab

09-10

11-12

13-14

15-16

17-18

19-20

Branch

Lab Contact

1,2,3-Trichloropropane

whole blood

4

●

●

●

●

●

●

TVB

DeJesus

AAA-Trifluorotoluene/α,α,α-Trifluorotoluene

whole blood

4

●

●

●

●

TVB

DeJesus

Benzonitrile

whole blood

4

WD

●

●

●

TVB

DeJesus

1-Bromopropane/Propyl bromide

whole blood

4

WD

d

TVB

DeJesus

Chloroethane

whole blood

4

●

●

●

●

TVB

DeJesus

Cyclohexane

whole blood

4

●

●

●

●

TVB

DeJesus

Ethyl acetate

whole blood

4

●

●

●

●

TVB

DeJesus

Heptane

whole blood

4

●

●

●

●

TVB

DeJesus

Methyl isobutyl ketone

whole blood

4

WD

WD

●

●

TVB

DeJesus

Methylcyclopentane

whole blood

4

●

●

●

●

TVB

DeJesus

Octane

whole blood

4

●

●

●

●

TVB

DeJesus

Tetrahydrofuran

whole blood

4

●

●

●

●

TVB

DeJesus

Vinyl bromide

whole blood

4

●

●

●

●

TVB

DeJesus

OAT

Ye

Perfluoroalkyl and Polyfluoroalkyl Substances: Surfactants
Perfluorobutane sulfonic acid (PFBuS)

serum

24

●

●

●

d

Pefluorodecanoic acid (PFDeA)

serum

24

●

●

●

●

●

●

OAT

Ye

Perflurododecanoic acid (PFDoA)

serum

24

●

●

●

●

●

●

OAT

Ye

Perfluoroheptanoic acid (PFHpA)

serum

24

●

●

●

d

OAT

Ye

Perfluorohexane sulfonic acid (PFHxS)

serum

24

●

●

●

●

●

●

OAT

Ye

Perfluorononanoic acid (PFNA)

serum

24

●

●

●

●

●

●

OAT

Ye

Perfluorooctanoic acid (PFOA)

serum

24

●

●

d

OAT

Ye

Perfluorooctane sulfonic acid (PFOS)

serum

24

●

●

d

OAT

Ye

Perfluorooctane sulfonamide (PFOSA)

serum

24

●

●

d

OAT

Ye

2-(N-Ethyl- Perfluorooctane sulfonamido) acetic acid
(Et-PFOSA-AcOH)

serum

24

●

●

d

OAT

Ye

2-(N-Methyl-perfluorooctane sulfonamido) acetic acid
(Me-PFOSA-AcOH)

serum

24

●

●

●

●

●

●

OAT

Ye

Perfluoroundecanoic acid (PFUA)

serum

24

●

●

●

●

●

●

OAT

Ye

●

●

●

OAT

Ye

●

●

●

OAT

Ye

●

●

●

OAT

Ye

●

●

●

OAT

Ye

●

●

●

OAT

Ye

●
surplus

●

OAT

Ye

n-Perfluorooctanoic acid (n-PFOA)

serum

24

Branched Perfluorooctanoic acid isomers (Sb-PFOA)*

serum

24

n-Perfluorooctane sulfonic (n-PFOS)

serum

24

Perfluoromethylheptane sulfonic acid isomers (SmPFOS)*

serum

24

●
surplus
●
surplus
●
surplus
●
surplus

Personal Care and Consumer Product Chemicals and Metabolites
Butyl paraben

urine

24

●

●

●

Hydroxy Butyl paraben

urine

24

Ethyl paraben

urine

24

●

●

●

●

●

●

OAT

Ye

Methyl paraben

urine

24

●

●

●

●

●

●

OAT

Ye

Propyl paraben

urine

24

●

●

●

●

●

●

OAT

Ye

Triclocarban

urine

24

●

●

●

●

OAT

Ye

Triclosan

urine

24

●

●

●

●

●

●

OAT

Ye

Bisphenol A

urine

24

●

●

●

●

●

●

OAT

Ye

Bisphenol F

urine

24

●

●

●

●

OAT

Ye

Bisphenol S

urine

24

●

●

●

●

OAT

Ye

Page 6 of 18

Chemical / Metabolite Name

Matrix

Lab

09-10

11-12

Di-hydroxy avobenzone

urine

24

Benzophenone-3

urine

24

●

●

4-tert -Octyl phenol

urine

24

●

d

2,4-Dichlorophenol

urine

24

●

2,5-Dichlorophenol

urine

24

urine

24

13-14

15-16

17-18

19-20

●
surplus

●

Branch

Lab Contact

OAT

Ye

●

●

●

●

OAT

Ye

●

●

●

●

●

OAT

Ye

●

●

●

●

●

●

OAT

Ye

●

●

●

●

●

●

OAT

Ye

●
surplus

●

●

●

OAT

Ye

Phthalate and Phthalate Alternative Metabolites
Mono-benzyl phthalate (MBzP)
Mono-2-hydroxybutyl phthalate (MHBP)

urine

24

Mono-n-butyl phthalate (MnBP)

urine

24

●

●

●

●

●

●

OAT

Ye

Mono-iso-butyl phthalate (MiBP)

urine

24

●

●

●

●

●

●

OAT

Ye

●
surplus

●

●

●

OAT

Ye

OAT

Ye

Mono-2-hydroxyisobutyl phthalate (MHiBP)

urine

24

Mono-cyclohexyl phthalate (MCHP)

urine

24

●

d

Mono-ethyl phthalate (MEP)

urine

24

●

●

●

●

●

●

OAT

Ye

Mono-2-ethylhexyl phthalate (MEHP)

urine

24

●

●

●

●

●

●

OAT

Ye

Mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHPP)

urine

24

●

●

●

●

●

●

OAT

Ye

Mono-(2-ethyl-5-oxohexyl) phthalate (MEOHP)

urine

24

●

●

●

●

●

●

OAT

Ye

Mono-(2-ethyl-5-carboxypentyl) phthalate (MECPP)

urine

24

●

●

●

●

●

●

OAT

Ye

Mono-carboxyisononyl phthalate (MCNP)

urine

24

●

●

●

●

●

●

OAT

Ye

Mono-oxoisodecyl phthalate (MODP)

urine

24

WD

WD

d

OAT

Ye

Mono-isononyl phthalate (MiNP)

urine

24

●

●

●

OAT

Ye

Mono-oxoisononyl phthalate (MONP)

urine

24

●
surplus

●

●

OAT

Ye

Mono-carboxyisoctyl phthalate (MCOP)

urine

24

●

●

●

●

●

●

OAT

Ye

Mono-methyl phthalate (MMP)

urine

24

●

●

d

OAT

Ye

Mono-(3-carboxypropyl) phthalate (MCPP)

urine

24

●

●

●

●

●

●

●

●

●

OAT

Ye

24

●
surplus

●

●

OAT

Ye

urine

24

●
surplus

●

●

OAT

Ye

urine

24

OAT

Ye

urine

24

urine

24

Bis(1-chloro-2-propyl) phosphate (BCPP)

urine

26

Bis(2-chloroethyl) phosphate (BCEtP)

urine

26

Bis(1,3-dichloro-2-propyl) phosphate (BDCPP)

urine

26

Dibenzyl phosphate (DBzP)

urine

26

Dibutyl phosphate (DBuP)

urine

26

Di-p-cresylphosphate (DpCP)

urine

26

Mono (2-ethyl-5-hydroxyhexyl) terephthalate
(MEHHTP)
Mono (2-ethyl-5-carboxypentyl) terephthalate
(MECPTP)
Mono-n-octyl phthalate (MOP)
Cyclohexane 1,2-dicarboxylic acid mono hydroxy
isononyl ester (MHNCH®)
Cyclohexane-1,2-dicarboxylic acid-mono(carboxyoctyl)
ester (MCOCH)
Flame Retardant Metabolites

Di-o-cresylphosphate (DoCP)

urine

urine

26

●

d
●

●
surplus
●
surplus
●
surplus
●
surplus

●
surplus

Page 7 of 18

●

●

●

●

OAT

Ye

WD

●

●

●

OAT

Ye

●
surplus
●
surplus
●
surplus
●
surplus
●
surplus
●
surplus
●
surplus

●
surplus
●
surplus
●
surplus
●
surplus

●

●

OAT

Ospina

●

●

OAT

Ospina

●

●

OAT

Ospina

●

●

OAT

Ospina

d

OAT

Ospina

d

OAT

Ospina

OAT

Ospina

●
surplus

●

●

Chemical / Metabolite Name
Di-cresyl phosphates (DCPs)

Matrix

Lab

urine

26

09-10

11-12
●
surplus
●
surplus
●
surplus

13-14

15-16

17-18

19-20

Branch

Lab Contact

●
surplus

●

OAT

Ospina

●
surplus
●
surplus

●
surplus
●
surplus
●
surplus

●

●

OAT

Ospina

●

●

OAT

Ospina

OAT

Calafat

OAT

Calafat

OAT

Calafat

Diphenyl phosphate (DPhP)

urine

26

2,3,4,5-Tetrabromobenzoic acid (TBBA)

urine

26

Ethylenethiourea (ETU)

urine

26

d

ortho -Phenylphenol

urine

26

●

Pentachlorophenol

urine

26

Propylenethiourea (PTU)

urine

26

d

OAT

Calafat

Atrazine

urine

26

d

OAT

Calafat

Atrazine mercapturate

urine

26

d

OAT

Calafat

Desethyl atrazine

urine

26

d

OAT

Calafat

Desethyl atrazine mercapturate

urine

26

d

OAT

Calafat

Desisopropyl atrazine

urine

26

d

OAT

Calafat

Desisopropyl atrazine mercapturate

urine

26

d

OAT

Calafat

Diaminochlorotriazine

urine

26

d

OAT

Calafat

2,4-Dichlorophenoxyacetic acid

urine

26

●

●

OAT

Ospina

2,4,5-Trichlorophenoxyacetic acid

urine

26

●

d

OAT

Ospina

Bensulfuron-methyl

urine

26

d

OAT

Calafat

Chlorsulfuron

urine

26

d

OAT

Calafat

Ethametsulfuron-methyl

urine

26

d

OAT

Calafat

Foramsulfuron

urine

26

d

OAT

Calafat

Halosulfuron

urine

26

d

OAT

Calafat

Mesosulfuron-methyl

urine

26

d

OAT

Calafat

Metsulfuron-methyl

urine

26

d

OAT

Calafat

Nicosulfuron

urine

26

d

OAT

Calafat

Oxasulfuron

urine

26

d

OAT

Calafat

Primisulfuron-methyl

urine

26

d

OAT

Calafat

Prosulfuron

urine

26

d

OAT

Calafat

Rimsulfuron

urine

26

d

OAT

Calafat

Sulfometuron-methyl

urine

26

d

OAT

Calafat

Sulfosulfuron

urine

26

d

OAT

Calafat

Thifensulfuron-methyl

urine

26

d

OAT

Calafat

Triasulfuron

urine

26

d

OAT

Calafat

Triflusulfuron-methyl

urine

26

d

OAT

Calafat

N,N-Diethyl-meta -toluamide (DEET)

urine

26

●

●

●

d

OAT

Ospina

3-(Diethylcarbamoyl)benzoic acid (DEET acid)

urine

26

●

●

●

●

●

●

OAT

Ospina

N,N-Diethyl-3-(hydroxymethyl)benzamide (Desethyl
hydroxy DEET)

urine

26

●

●

●

d

WD

WD

OAT

Ospina

●
surplus

●

●

OAT

Ospina

●

OAT

Ospina

●

OAT

Ospina

Fungicides and Metabolites

d

Herbicides and Metabolites

●

●

●

●

Herbicides: Substituted Ureas

Insect Repellent

3-(Ethylcarbamoyl)benzoic acid (MEA)

urine

26

Acetamiprid

urine

26

Clothianidine

urine

26

Neonicotinoid Pesticides and Metabolites
●
surplus
●
surplus

Page 8 of 18

Chemical / Metabolite Name

Matrix

Lab

Imidacloprid

urine

26

5-Hydroxyimidacloprid

urine

26

N-Desmethylacetamiprid

urine

26

Thiacloprid

urine

26

09-10

11-12

13-14

15-16

17-18

●
surplus
●
surplus
●
surplus
●
surplus

19-20

Branch

Lab Contact

●

OAT

Ospina

●

OAT

Ospina

●

OAT

Ospina

●

OAT

Ospina

Organophosphorus Insecticides: Dialkyl Phosphate Metabolites
Dimethylphosphate

urine

26

d

●

●

●

●

●

OAT

Ospina

Dimethylthiophosphate

urine

26

d

●

●

●

●

●

OAT

Ospina

Dimethyldithiophosphate

urine

26

d

●

●

●

●

●

OAT

Ospina

Diethylphosphate

urine

26

d

●

●

●

●

●

OAT

Ospina

Diethylthiophosphate

urine

26

d

●

●

●

●

●

OAT

Ospina

Diethyldithiophosphate

urine

26

d

●

●

●

●

●

OAT

Ospina

●
surplus
●
surplus

●
surplus
●
surplus

●
surplus
●
surplus

OAT

Ospina

OAT

Ospina

N-(phosphonomethyl)glycine (Glyphosate)

urine

26

Aminomethlphosphonic acid (AMPA)

urine

26

Organophosphorus Insecticides: Specific Pesticides and Metabolites
Malathion dicarboxylic acid

urine

26

●

●

●

●

●

●

OAT

Ospina

3,5,6-Trichloro-2-pyridinol (TCPy)

urine

26

●

●

●

●

●

●

OAT

Ospina

2-diethylamino-6-methyl pyrimidin-4-ol

urine

OAT

Ospina

2-Isopropyl-4-methyl-6-hydroxypyrimidine
(oxypyrimidine)

urine

26

para- Nitrophenol

urine

Dimethoate

urine

Omethoate
Acephate
Methamidaphos

●

●

●

●

●

●

OAT

Ospina

26

●

●

●

●

●

●

OAT

Ospina

26

d

OAT

Calafat

urine

26

d

OAT

Calafat

urine

26

d

OAT

Calafat

urine

26

d

OAT

Calafat

Carbofuranphenol

urine

26

OAT

Calafat

2-Isopropoxyphenol

urine

26

OAT

Calafat

cis -3-(2,2-Dichlorovinyl)-2,2-dimethylcyclopropane
carboxylic acid (cis-DCCA)

urine

26

d

OAT

Ospina

trans -3-(2,2-Dichlorovinyl)-2,2-dimethylcyclopropane
carboxylic acid (trans-DCCA)

urine

26

●

●

●

●

●

●

OAT

Ospina

3-Phenoxybenzoic acid (3PBA)

urine

26

●

●

●

●

●

●

OAT

Ospina

4-Fluoro-3-phenoxybenzoic acid (4F3PBA)

urine

26

●

●

●

●

●

●

OAT

Ospina

cis -3-(2,2-Dibromovinyl)-2,2-dimethylcyclopropane
carboxylic acid (cis-DBCA)

urine

26

●

●

●

●

●

●

OAT

Ospina

Aldrin

serum

28

OAT

Sjodin

Dieldrin

serum

28

OAT

Sjodin

Oxychlordane

serum

28

OAT

Sjodin

Heptachlor Epoxide

serum

28

OAT

Sjodin

trans -Nonachlor

serum

28

P

P

P

P

●

●

OAT

Sjodin

p,p'- DDT

serum

28

P

P

P

P

●

●

OAT

Sjodin

p,p' -DDE

serum

28

P

P

P

P

●

●

OAT

Sjodin

Other Pesticide Metabolites

Pyrethroid Pesticides

Organochlorine Pesticides and Metabolites

P

P

Page 9 of 18

P

P

●

●

Chemical / Metabolite Name

Matrix

Lab

o,p' -DDT

serum

Endrin

09-10

11-12

13-14

15-16

Branch

Lab Contact

28

OAT

Sjodin

serum

28

OAT

Sjodin

Hexachlorobenzene

serum

28

P

P

P

P

●

●

OAT

Sjodin

beta -Hexachlorocyclohexane

serum

28

P

P

P

P

●

●

OAT

Sjodin

gamma -Hexachlorocyclohexane

serum

28

P

P

d

OAT

Sjodin

Mirex

serum

28

P

P

P

OAT

Sjodin

2,4,5-Trichlorophenol

urine

24

●

d

OAT

Ye

2,4,6-Trichlorophenol

urine

24

●

d

OAT

Ye

P

17-18

●

19-20

●

Polybrominated Diphenyl Ethers and Brominated Biphenyl 153
2,2',4’-Tribromodiphenyl ether (BDE 17)

serum

28

P

P

P

P

●

●

OAT

Sjodin

2,4,4’-Tribromodiphenyl ether (BDE 28)

serum

28

P

P

P

P

●

●

OAT

Sjodin

2,2’,4,4’-Tetrabromodiphenyl ether (BDE 47)

serum

28

P

P

P

P

●

●

OAT

Sjodin

2,3',4,4'-Tetrabromodiphenyl ether (BDE 66)

serum

28

P

P

P

P

●

d

OAT

Sjodin

2,2’,3,4,4’-Pentabromodiphenyl ether (BDE 85)

serum

28

P

P

P

P

●

●

OAT

Sjodin

2,2’,4,4’,5-Pentabromodiphenyl ether (BDE 99)

serum

28

P

P

P

P

●

●

OAT

Sjodin

2,2’,4,4’,6-Pentabromodiphenyl ether (BDE 100)

serum

28

P

P

P

P

●

●

OAT

Sjodin

2,2’,4,4’,5,5’-Hexabromodiphenyl ether (BDE 153)

serum

28

P

P

P

P

●

●

OAT

Sjodin

2,2’,4,4’,5,6’-Hexabromodiphenyl ether (BDE 154)

serum

28

P

P

P

P

●

●

OAT

Sjodin

2,2’,3,4,4’,5’,6-Heptabromodiphenyl ether (BDE 183)

serum

28

P

P

P

P

●

●

OAT

Sjodin

2,2',3,3',4,4',5,5',6,6'-Decabromodiphenyl ether (BDE
209)

serum

28

P

P

P

P

●

●

OAT

Sjodin

2,2’,4,4’,5,5’-Hexabromobiphenyl (BB 153)

serum

28

P

P

P

P

●

●

OAT

Sjodin

1,2,3,4,6,7,8-Heptachlorodibenzo-p -dioxin (HpCDD)

serum

28

P

P

P

P

●

P

OAT

Sjodin

1,2,3,4,7,8-Hexachlorodibenzo-p -dioxin (HxCDD)

serum

28

P

P

P

P

●

P

OAT

Sjodin

1,2,3,6,7,8-Hexachlorodibenzo-p -dioxin (HxCDD)

serum

28

P

P

P

P

●

P

OAT

Sjodin

1,2,3,7,8,9-Hexachlorodibenzo-p -dioxin (HxCDD)

serum

28

P

P

P

P

●

P

OAT

Sjodin

1,2,3,4,6,7,8,9-Octachlorodibenzo-p -dioxin (OCDD)

serum

28

P

P

P

P

●

P

OAT

Sjodin

1,2,3,7,8-Pentachlorodibenzo-p -dioxin (PeCDD)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,3,7,8-Tetrachlorodibenzo-p -dioxin (TCDD)

serum

28

P

P

P

P

●

P

OAT

Sjodin

1,2,3,4,6,7,8-Heptachlorodibenzofuran (HpCDF)

serum

28

P

P

P

P

●

P

OAT

Sjodin

1,2,3,4,7,8,9-Heptachlorodibenzofuran (HpCDF)

serum

28

P

P

P

P

●

P

OAT

Sjodin

1,2,3,4,7,8-Hexachlorodibenzofuran (HxCDF)

serum

28

P

P

P

P

●

P

OAT

Sjodin

1,2,3,6,7,8-Hexachlorodibenzofuran (HxCDF)

serum

28

P

P

P

P

●

P

OAT

Sjodin

Polychlorinated Dibenzo-p -dioxins

Polychlorinated Dibenzofurans

Page 10 of 18

Chemical / Metabolite Name

Matrix

Lab

09-10

11-12

13-14

15-16

17-18

19-20

Branch

Lab Contact

1,2,3,7,8,9-Hexachlorodibenzofuran (HxCDF)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,3,4,6,7,8-Hexachlorodibenzofuran (HxCDF)

serum

28

P

P

P

P

●

P

OAT

Sjodin

1,2,3,4,6,7,8,9-Octachlorodibenzofuran (OCDF)

serum

28

P

P

P

P

●

P

OAT

Sjodin

1,2,3,7,8-Pentachlorodibenzofuran (PeCDF)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,3,4,7,8-Pentachlorodibenzofuran (PeCDF)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,3,7,8-Tetrachlorodibenzofuran (TCDF)

serum

28

P

P

P

P

●

P

OAT

Sjodin

3,4,4',5-Tetrachlorobiphenyl (PCB 81)

serum

28

P

P

P

P

●

P

OAT

Sjodin

3,3',4,4',5-Pentachlorobiphenyl (PCB 126)

serum

28

P

P

P

P

●

P

OAT

Sjodin

3,3',4,4',5,5'-Hexachlorobiphenyl (PCB 169)

serum

28

P

P

P

P

●

P

OAT

Sjodin

Dioxin-like Polychlorinated Biphenyls: Coplanar PCBs

Dioxin-like Polychlorinated Biphenyls: Mono-ortho- Substituted PCBs
2,3,3',4,4'-Pentachlorobiphenyl (PCB 105)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,3,3',4,4'-Pentachlorobiphenyl (PCB 114)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,3',4,4',5-Pentachlorobiphenyl (PCB 118)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2',3,4,4',5-Pentachlorobiphenyl (PCB 123)

serum

28

d

●

P

OAT

Sjodin

2,3,3',4,4',5-Hexachlorobiphenyl (PCB 156)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,3,3',4,4',5'-Hexachlorobiphenyl (PCB 157)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,3',4,4',5,5'-Hexachlorobiphenyl (PCB 167)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,3,3’,4,4’,5,5’-Heptachlorobiphenyl (PCB 189)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,4,4'-Trichlorobiphenyl (PCB 28)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,2'3,5'-Tetrachloro biphenyl (PCB 44)

serum

28

d

OAT

Sjodin

2,2',4,5'-Tetrachloro biphenyl (PCB 49)

serum

28

d

OAT

Sjodin

2,2',5,5'-Tetrachlorobiphenyl (PCB 52)

serum

28

d

OAT

Sjodin

2,3',4,4'-Tetrachlorobiphenyl (PCB 66)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,4,4',5-Tetrachlorobiphenyl (PCB 74)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,2’,3,4,5’-Pentachlorobiphenyl (PCB 87)

serum

28

d

OAT

Sjodin

2,2',4,4',5-Pentachlorobiphenyl (PCB 99)

serum

28

P

OAT

Sjodin

2,2',4,5,5'-Pentachlorobiphenyl (PCB 101)

serum

28

d

OAT

Sjodin

2,3,3’,4’,6-Pentachlorobiphenyl (PCB 110)

serum

28

d

OAT

Sjodin

2,2',3,3',4,4'-Hexachlorobiphenyl (PCB 128)

serum

28

d

OAT

Sjodin

2,2',3,4,4',5' and 2,3,3’,4,4’,6-Hexachlorobiphenyl (PCB
138 & 158)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,2',3,4',5,5'-Hexachlorobiphenyl (PCB 146)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,2’,3,4’,5’,6-Hexachlorobiphenyl (PCB 149)

serum

28

d

OAT

Sjodin

2,2’,3,5,5’,6-Hexachlorobiphenyl (PCB 151)

serum

28

d

OAT

Sjodin

Polychlorinated Biphenyls: Non-Dioxin-Like

P

Page 11 of 18

P

P

●

P

Chemical / Metabolite Name

Matrix

Lab

09-10

11-12

13-14

15-16

17-18

19-20

Branch

Lab Contact

2,2',4,4',5,5'-Hexachlorobiphenyl (PCB 153)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,2',3,3',4,4',5-Heptachlorobiphenyl (PCB 170)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,2',3,3',4,5,5'-Heptachlorobiphenyl (PCB 172)

serum

28

d

OAT

Sjodin

2,2',3,3',4,5',6'-Heptachlorobiphenyl (PCB 177)

serum

28

d

OAT

Sjodin

2,2',3,3',5,5',6-Heptachlorobiphenyl (PCB 178)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,2',3,4,4',5,5'-Heptachlorobiphenyl (PCB 180)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,2',3,4,4',5',6-Heptachlorobiphenyl (PCB 183)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,2',3,4',5,5',6-Heptachlorobiphenyl (PCB 187)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,2’,3,3’,4,4’,5,5’-Octachlorobiphenyl (PCB 194)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,2’,3,3’,4,4’,5,6-Octachlorobiphenyl (PCB 195)

serum

28

d

OAT

Sjodin

2,2’,3,3’,4,4’,5,6’ and 2,2’,3,4,4’,5,5’,6Octachlorobiphenyl (PCB 196 & 203)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,2’,3,3’,4,5,5’,6-Octachlorobiphenyl (PCB 199)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,2’,3,3’,4,4’,5,5’,6-Nonachlorobiphenyl (PCB 206)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2,2',3,3',4,4',5,5',6,6'-Decachloro biphenyl (PCB 209)

serum

28

P

P

P

P

●

P

OAT

Sjodin

2-Hydroxyfluorene

urine

31

●

●

●

●

●

●

OAT

Ye

3-Hydroxyfluorene

urine

31

●

●

●

●

●

●

OAT

Ye

9-Hydroxyfluorene

urine

31

●

●

d

OAT

Ye

1-Hydroxyphenanthrene

urine

31

●

●

●

OAT

Ye

2-Hydroxyphenanthrene

urine

31

●

●

d

OAT

Ye

3-Hydroxyphenanthrene

urine

31

●

●

d

OAT

Ye

2 & 3-Hydroxyphenanthrene

urine

31

OAT

Ye

4-Hydroxyphenanthrene

urine

31

●

●

d

OAT

Ye

1-Hydroxypyrene

urine

31

●

●

●

●

●

●

OAT

Ye

1-Hydroxynapthalene (1-Naphthol)

urine

31

●

●

●

●

●

●

OAT

Ye

2-Hydroxynapthalene (2-Naphthol)

urine

31

●

●

●

●

●

●

OAT

Ye

5-acetylamino-6-amino-3-methyluracil

urine

54

●

●

●

d

NBB

Ryback

1-methyluric acid

urine

54

●

●

●

d

NBB

Ryback

3-methyluric acid

urine

54

●

●

●

d

NBB

Ryback

7-methyluric acid

urine

54

●

●

●

d

NBB

Ryback

1,3-dimethyluric acid

urine

54

●

●

●

d

NBB

Ryback

1,7-dimethyluric acid

urine

54

●

●

●

d

NBB

Ryback

3,7-dimethyluric acid

urine

54

●

●

●

d

NBB

Ryback

1,3,7-trimethyluric acid

urine

54

●

●

●

d

NBB

Ryback

1-methylxanthine

urine

54

●

●

●

d

NBB

Ryback

3-methylxanthine

urine

54

●

●

●

d

NBB

Ryback

7-methylxanthine

urine

54

●

●

●

d

NBB

Ryback

1,3-dimethylxanthine (theophylline)

urine

54

●

●

●

d

NBB

Ryback

1,7-dimethylxanthine (paraxanthine)

urine

54

●

●

●

d

NBB

Ryback

3,7-dimethylxanthine (theobromine)

urine

54

●

●

●

d

NBB

Ryback

1,3,7-trimethylxanthine (caffeine)

urine

54

●

●

●

d

NBB

Ryback

Polycyclic Aromatic Hydrocarbon Metabolites

●

●

●

●

●

●

●

Caffeine and Metabolites

Fatty acids (30)

Page 12 of 18

Chemical / Metabolite Name
Capric acid (C10:0)
Lauric acid (C12:0)
Myristic acid (14:0)
Pentadecanoic acid (C15:0)
Palmitic acid (16:0)
Margaric acid (C17:0)
Stearic acid (18:0)
Arachidic acid (20:0)
Docosanoic acid (22:0)
Tricosanoic acid (C23:0)
Lignoceric acid (24:0)
Myristoleic acid (14:1n-5)
Palmitoleic acid (16:1n-7)
cis-Vaccenic acid (18:1n-7)
Oleic acid (18:1n-9)
Eicosenoic acid (20:1n-9)
Docosenoic acid (22:1n-9)
Nervonic acid (24:1n-9)
Linoleic acid (18:2n-6)
alpha-Linolenic acid (18:3n-3)
gamma-Linolenic acid (18:3n-6)
Stearidonic acid (C18:4n-3)
Eicosadienoic acid (20:2n-6)
homo-gamma-Linolenic acid (20:3n-6)
Eicosatrienoic acid (C20:3n-9)
Arachidonic acid (20:4n-6)
Eicosapentaenoic acid (20:5n-3)
Docosatetraenoic acid (22:4n-6)
Docosapentaenoic acid (22:5n-3)
Docosapentaenoic acid (22:5n-6)
Docosahexaenoic acid (22:6n-3)

Matrix
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum
plasma
/serum

Lab

09-10

11-12

13-14

15-16

54

●

●

54

●

●

54

●

54
54

17-18

19-20

Branch

Lab Contact

d

NBB

Schleicher

d

NBB

Schleicher

●

d

NBB

Schleicher

●

●

d

NBB

Schleicher

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

54

●

●

d

NBB

Schleicher

Fat-Soluble Vitamins and Micronutrients
Vitamin A

serum

54

●

●

NBB

Schleicher

Vitamin E

serum

54

●

●

NBB

Schleicher

Retinyl palmitate

serum

54

●

●

NBB

Schleicher

Retinyl stearate

serum

54

●

●

NBB

Schleicher

gamma- Tocopherol

serum

54

●

●

NBB

Schleicher

delta- Tocopherol

serum

54

●

NBB

Schleicher

alpha -carotene

serum

54

●

●

NBB

Schleicher

trans-beta- Carotene

serum

54

●

●

NBB

Schleicher

cis-beta- Carotene

serum

54

●

●

NBB

Schleicher

alpha- Cryptoxanthin

serum

54

●

●

NBB

Schleicher

beta- Cryptoxanthin

serum

54

●

●

NBB

Schleicher

Lutein/zeaxanthin combined or measured and reported
as separate analytes

serum

54

●

●

NBB

Schleicher

trans- Lycopene

serum

54

●

●

NBB

Schleicher

Total lycopene

serum

54

●

●

NBB

Schleicher

25-OH Vitamin D (D2 + D3)

serum

54

●

●

NBB

Schleicher

●

●

Page 13 of 18

●

●

Chemical / Metabolite Name

Matrix

Lab

09-10

11-12

13-14

15-16

17-18

19-20

Branch

Lab Contact

25-OH Vitamin D2

serum

54

●

●

●

●

●

●

NBB

Schleicher

25-OH Vitamin D3

serum

54

●

●

●

●

●

●

NBB

Schleicher

epimer-25-OH Vitamin D3

serum

54

●

●

●

●

●

●

NBB

Schleicher

Ferritin

serum

54

●

d

●

●

●

NBB

Pfeiffer

Transferrin receptor

serum

54

●

d

●

●

●

NBB

Pfeiffer

Iron

serum

NBB

Pfeiffer

TIBC

serum

NBB

Pfeiffer

Transferrin saturation

serum

NBB

Pfeiffer

Protoporphyrin

serum

NBB

Pfeiffer

Iron-Status and Inflammation Indicators

Phytoestrogens
Daidzein

urine

54

●

d

NBB

Ryback

Enterodiol

urine

54

●

d

NBB

Ryback

Enterolactone

urine

54

●

d

NBB

Ryback

Equol

urine

54

●

d

NBB

Ryback

Genistein

urine

54

●

d

NBB

Ryback

O-Desmethylangolensin

urine

54

●

d

NBB

Ryback

serum

54

●

d

NBB

Pfeiffer

RBC

54

●

●

●

●

●

●

NBB

Pfeiffer

●

●

●

●

●

NBB

Pfeiffer

Water Soluble Vitamins and Related Compounds
Folate (serum)
Folate (RBC)
Folate forms by LC-MS/MS (serum)
Total folate (calculated)
5-Methyltetrahydrofolate

serum

54

●

●

●

●

●

NBB

Pfeiffer

Folic acid

serum

54

●

●

●

●

●

NBB

Pfeiffer

5-Formyltetrahydrofolate

serum

54

●

●

●

●

●

NBB

Pfeiffer

Tetrahydrofolate

serum

54

●

●

●

●

●

NBB

Pfeiffer

5,10-Methenyltetrahydrofolate

serum

54

●

●

●

●

●

NBB

Pfeiffer

MeFox oxidation product

serum

54

●

●

●

●

●

NBB

Pfeiffer

Folate forms by LC-MS/MS (RBC)
Total folate (calculated)

RBC

●

NBB

Pfeiffer

5-Methyltetrahydrofolate

RBC

54

●

NBB

Pfeiffer

Folic acid

RBC

54

●

NBB

Pfeiffer

5-Formyltetrahydrofolate

RBC

54

●

NBB

Pfeiffer

Tetrahydrofolate

RBC

54

●

NBB

Pfeiffer

5,10-Methenyltetrahydrofolate

RBC

54

●

NBB

Pfeiffer

MeFox oxidation product

RBC

54

●

NBB

Pfeiffer

Homocysteine

NBB

Pfeiffer

●

●

d

NBB

Pfeiffer

●

●

d

NBB

Pfeiffer

NBB

Pfeiffer

NBB

Pfeiffer

plasma
plasma/seru
m

54

Vitamin B12

serum

54

Vitamin B6 (pyridoxal-5'-phosphate)

serum

●

d

Vitamin B6 (4-pyridoxic acid)

serum

●

d

Vitamin C (ascorbic acid)

serum

54

urine

59

Anatabine

urine

59

Cotinine

serum

59

Cotinine

urine

59

Methylmalonic acid

●

●

NBB

Pfeiffer

Tobacco Biomarkers: Cotinine and Nicotine Analogs
Anabasine

●

●

Page 14 of 18

●

●

●

●

TVB

Feng/Wang

●

●

●

●

TVB

Feng/Wang

●

●

●

●

TVB

Sosnoff

●

●

●

●

TVB

Feng/Wang

Chemical / Metabolite Name

Matrix

Lab

Cotinine-n-oxide

urine

Hydroxycotinine

serum

Hydroxycotinine

09-10

11-12

13-14

15-16

17-18

19-20

Branch

Lab Contact

59

●

●

●

●

TVB

Feng/Wang

59

●

●

●

●

TVB

Sosnoff

urine

59

●

●

●

●

TVB

Feng/Wang

Norcotinine

urine

59

●

●

WD

TVB

Feng/Wang

Nicotine-1'N-oxide

urine

59

●

●

●

●

TVB

Feng/Wang

Nornicotine

urine

59

●

●

●

●

TVB

Feng/Wang

Nicotine

urine

59

●

●

●

●

TVB

Feng/Wang

4-Hydroxy-4-(3-pyridyl) butanoic acid

urine

59

●

●

TVB

Feng/Wang

1-Aminonaphthalene

urine

59

●

TVB

Seyler/Wang

2-Aminonaphthalene

urine

59

●

WD

●

●

TVB

Seyler/Wang

4-Aminobiphenyl

urine

59

●

WD

●

●

TVB

Seyler/Wang

Anisidine

urine

59

●

WD

●

●

TVB

Seyler/Wang

2,6-Dimethylaniline

urine

59

●

WD

●

●

TVB

Seyler/Wang

Quinoline

urine

59

WD

WD

WD

WD

TVB

Seyler/Wang

o -Toluidine

urine

59

●

WD

●

●

TVB

Seyler/Wang

3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1)

urine

59

●

d

WD

●

TVB

Wang

2-Amino-3-methyl-9H-pyriodo[2,3-b]indole (MeA-α-C)

urine

59

●

d

WD

●

TVB

Wang

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
(Ph1P)

urine

59

●

d

WD

●

TVB

Wang

2-Amino-9H-pyrido[2,3-b]indole (A-α-C)

urine

59

●

d

WD

●

TVB

Wang

2-Amino-3-methylimidazo[4,5-f]quinoline (IQ)

urine

59

●

d

WD

●

TVB

Wang

2-Amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole (GluP1)

urine

59

●

d

WD

●

TVB

Wang

2-Aminodipyrido[1,2-a:3',2'-d] imidazole (GLU-P2)

urine

59

●

d

WD

●

TVB

Wang

Harman

urine

59

●

d

WD

●

TVB

Wang

1-Methyl-3-amino-5H-pyrido[4,3-b]indole (Trp-P-2)

urine

59

●

d

WD

●

TVB

Wang

Norharman

urine

59

●

d

WD

●

TVB

Wang

●

●

WD

●

TVB

Wang

Tobacco Biomarkers: Aromatic Amines
WD

Tobacco Biomarkers: Heterocyclic Amines

Tobacco Biomarkers: Tobacco-specific Nitrosamines (TSNAs)
●

●

4-(Methylnitrosamino)-1-(3-pyridyl)-1-Butanol (NNAL)

urine

59

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

urine

59

WD

WD

WD

TVB

Wang

N'-Nitrosanabasine (NAB)

urine

59

●

WD

WD

TVB

Wang

N'-Nitrosanatabine (NAT)

urine

59

●

WD

WD

TVB

Wang

N'-Nitrosonornicotine (NNN)

urine

59

●

WD

WD

TVB

Wang

urine

59

surplus

●

WD

d

TVB

Seyler/Wang

WD

WD

d

Tobacco Biomarkers: Volatile N-Nitrosamines
N-Nitrosodiethylamine (NDEA)
N-nitrosodimethylamine (NDMA)

urine

59

surplus

TVB

Seyler/Wang

N-Nitrosoethylmethylamine (NMEA)

urine

59

surplus

●

WD

d

TVB

Seyler/Wang

N-nitrosomorpholine (NMOR)

urine

59

surplus

●

WD

d

TVB

Seyler/Wang

N-Nitrosopiperidine (NPIP)

urine

59

surplus

●

WD

d

TVB

Seyler/Wang

N-Nitrosopyrrolidine (NPYR)

urine

59

surplus

●

WD

d

TVB

Seyler/Wang

Acrylamide

packed rbcs

60

d

no prbc

●

●

●

●

CCB

Vesper

Glycidamide

packed rbcs

60

d

no prbc

●

●

●

●

CCB

Vesper

Adducts of Hemoglobin

Page 15 of 18

Chemical / Metabolite Name

Matrix

Lab

Ethylene Oxide

packed rbcs

Formaldehyde

09-10

11-12

13-14

15-16

17-18

19-20

Branch

Lab Contact

60

●

●

●

●

CCB

Vesper

packed rbcs

60

●

●

●

●

CCB

Vesper

Estradiol (E2)

serum

60

●

●

d

●

CCB

Vesper

Testosterone (TT)

serum

60

●

●

d

●

CCB

Vesper

17α-Hydroxyprogesterone (17-OHP)

serum

60

●

CCB

Vesper

Progesterone (P4)

serum

60

●

CCB

Vesper

Estrone (E1)

serum

60

●

CCB

Vesper

Estrone sulfate (E1S)

serum

60

●

CCB

Vesper

Androstenedione (AD)

serum

60

●

CCB

Vesper

Dehydroepiandrosterone sulfate (DHEAS)

serum

60

●

CCB

Vesper

Steroid Hormone Binding Globulin

serum

60

●

CCB

Vesper

Anti-Mullerian hormone (AMH)

serum

60

●

CCB

Vesper

Follicle stimulating hormone (FSH)

serum

60

●

CCB

Vesper

Luteinizing hormone (LH)

serum

60

●

CCB

Vesper

trans -9-Hexadecenoic acid

plasma

60

●

d

CCB

Vesper

trans -9-Octadecenoic acid

plasma

60

●

d

CCB

Vesper

trans,trans -9,12-Octadecadienoic acid

plasma

60

●

d

CCB

Vesper

trans- 11-Octadecanoic acid

plasma

60

●

d

CCB

Vesper

Antimony

urine

61

●

●

●

●

●

●

IRAT

Caldwell

Arsenic (total)

urine

61

●

●

●

●

●

●

IRAT

Caldwell

Arsenic (V) acid

urine

61

●

●

●

●

●

●

IRAT

Caldwell

Arsenobetaine

urine

61

●

●

●

●

●

●

IRAT

Caldwell

Arsenocholine

urine

61

●

●

●

●

●

●

IRAT

Caldwell

Arsenous (III) acid

urine

61

●

●

●

●

●

●

IRAT

Caldwell

Dimethylarsinic acid

urine

61

●

●

●

●

●

●

IRAT

Caldwell

Monomethylarsonic acid

urine

61

●

●

●

●

●

●

IRAT

Caldwell

Trimethylarsine oxide

urine

●

●

d

IRAT

Caldwell

Barium

urine

61

●

●

●

IRAT

Caldwell

Beryllium

urine

61

●

d

IRAT

Caldwell

Cadmium

whole blood

61

●

●

●

●

●

●

IRAT

Caldwell

Cadmium

urine

61

●

●

●

●

●

●

IRAT

Caldwell

Cesium

urine

61

●

●

●

●

●

●

IRAT

Caldwell

Chromium

urine

61

●

●

IRAT

Caldwell

Chromium

whole blood

61

●

●

●

IRAT

Caldwell

Cobalt

whole blood

61

●

●

●

IRAT

Caldwell

Cobalt

urine

61

●

IRAT

Caldwell

Hormones and Binding Protein

●

●

●

d

trans Fatty Acids

Metals and Metalloids

●

●

●

●

●

●

●

●

serum

61

●

●

●

d

IRAT

Caldwell

Lead

whole blood

61

●

●

●

●

●

●

IRAT

Caldwell

Lead

urine

61

●

●

●

●

●

●

IRAT

Caldwell

whole blood

61

●

●

●

●

●

IRAT

Caldwell

Copper

Manganese

urine

61

●

●

●

●

●

IRAT

Caldwell

Mercury (total)

whole blood

61

●

●

●

●

●

●

IRAT

Caldwell

Mercury (inorganic)

whole blood

61

●

●

●

●

●

●

IRAT

Caldwell

Manganese

Page 16 of 18

Chemical / Metabolite Name

Matrix

Lab

Mercury (ethyl)

whole blood

Mercury (methyl)

09-10

11-12

13-14

15-16

17-18

19-20

Branch

Lab Contact

61

●

●

●

●

●

IRAT

Caldwell

whole blood

61

●

●

●

●

●

IRAT

Caldwell

Mercury

urine

61

●

●

●

●

●

●

IRAT

Caldwell

Molybdenum

urine

61

●

●

●

●

●

●

IRAT

Caldwell

Nickel

urine

61

●

●

IRAT

Caldwell

Platinum

urine

61

●

d

IRAT

Caldwell

Selenium

whole blood

61

●

●

●

●

IRAT

Caldwell

Selenium

serum

61

●

●

●

d

IRAT

Caldwell

Strontium

urine

61

●

●

●

●

●

IRAT

Caldwell

Thallium

urine

61

●

●

●

●

●

IRAT

Caldwell

Tin

urine

61

●

●

●

●

●

IRAT

Caldwell

Tungsten

urine

61

●

●

●

●

●

●

IRAT

Caldwell

Uranium

urine

61

●

●

●

●

●

●

IRAT

Caldwell

Zinc

serum

61

●

●

●

d

IRAT

Caldwell

Iodine

urine

61

●

●

●

●

●

IRAT

Caldwell

Fluoride

urine

61

●

●

d

IRAT

Caldwell

Perchlorate

urine

62

TVB

Morel

Perchlorate

water

Thiocyanate

urine

62

Nitrate

urine

62

Nitrate

water

Fluoride

urine

Iodide

water

●

●

●

Perchlorate and Other Anions
●

●

●

●

●

●

TVB

Morel

●

●

●

●

●

●

TVB

Morel

●

●

●

●

●

●

TVB

Morel

TVB

Morel

TVB

Morel

TVB

Morel

d

d
62

WD

WD

d

d

Urinary Aromatic Diamines/Amines (formerly Diisocyanate metabolites and urinary amines)
2,4-Diaminotoluene (4TDA)

urine

62

●

●

●

TVB

2,6-Diaminotoluene (6TDA)

urine

62

●

●

●

TVB

4,4'-Diaminodiphenylmethane (4MDA)

urine

62

●

●

●

TVB

1,5-Diaminonaphthalene (5NDA)

urine

62

●

●

●

TVB

p -Phenylenediamine (PPDA)

urine

62

●

●

●

TVB

o- Phenylenediamine (OPDA)

urine

62

WD

d

TVB

Bhandari/
De Jesus
Bhandari/
De Jesus
Bhandari/
De Jesus
Bhandari/
De Jesus
Bhandari/
De Jesus
Bhandari/
De Jesus

Volatile Organic Compound Metabolites (VOC metabolites)
N-Acetyl-S-(2-carbamoylethyl)-L-cysteine (AAMA)

urine

62

●

●

●

●

●

TVB

DeJesus

N-Acetyl-S-(N-methylcarbamoyl)-L-cysteine (AMCA)

urine

62

●

●

●

●

●

TVB

DeJesus

2-Aminothiazoline-4-carboxylic acid (ATCA)

urine

62

●

●

●

●

●

TVB

DeJesus

N-Acetyl-S-(benzyl)-L-cysteine (BMA)

urine

62

●

●

●

d

TVB

DeJesus

N-Acetyl-S-(n-propyl)-L-cysteine (BPMA)

urine

62

●

●

●

●

●

TVB

DeJesus

N-Acetyl-S- (2-carboxyethyl)-L-cysteine (CEMA)

urine

62

●

●

●

●

●

TVB

DeJesus

N-acetyl-S-(1-cyano-2-hydroxyethyl)-L-cysteine (CYHA)

urine

62

●

●

●

TVB

DeJesus

N-Acetyl-S-(2-cyanoethyl)-L-cysteine (CYMA)

urine

62

●

●

●

TVB

DeJesus

●

Page 17 of 18

●

Chemical / Metabolite Name

Matrix

Lab

N-Acetyl-S-(1,2-dichlorovinyl)-L-cysteine (1DCV)

urine

N-Acetyl-S-(2,2-dichlorovinyl)-L-cysteine (2DCV)

11-12

13-14

15-16

17-18

Branch

Lab Contact

62

●

●

●

d

TVB

DeJesus

urine

62

●

●

●

d

TVB

DeJesus

N-Acetyl-S- (3,4-dihydroxybutyl)-L-cysteine (DHBM)

urine

62

●

●

●

●

TVB

DeJesus

N-Acetyl-S-(dimethylphenyl)-L-cysteine (DPMA)

urine

62

N-Acetyl-S-(2-carbamoyl-2-hydroxyethyl)-L-cysteine
(GAMA)

●

●

●

WD

TVB

DeJesus

urine

62

●

●

●

●

●

TVB

DeJesus

N-Acetyl-S- (2-hydroxyethyl)-L-cysteine (HEMA)

urine

62

●

●

●

●

●

TVB

DeJesus

N-Acetyl-S- (3-hydroxypropyl)-L-cysteine (HPMA)

urine

62

●

●

●

●

●

TVB

DeJesus

N-Acetyl-S- (2-hydroxypropyl)-L-cysteine (HPM2)

urine

62

●

●

●

●

●

TVB

DeJesus

urine

62

●

●

●

●

●

TVB

DeJesus

urine

62

●

●

●

d

TVB

DeJesus

N-Acetyl-S- (2-hydroxy-3-butenyl)-L-cysteine (MHB2)

urine

62

●

●

●

d

TVB

DeJesus

N-Acetyl-S- (4-hydroxy-2-butenyl)-L-cysteine (MHB3)

urine

62

●

●

●

●

●

TVB

DeJesus

N-Acetyl-S-(phenyl-2-hydroxyethyl)-L-cysteine (PHEM)

urine

62

●

●

●

●

●

TVB

DeJesus

N-Acetyl-S-(phenyl)-L-cysteine (PMA)

urine

62

●

●

●

●

●

TVB

DeJesus

N-Acetyl-S-(trichlorovinyl)-L-cysteine (TCVM)

urine

62

●

●

●

d

TVB

DeJesus

Mandelic acid (MADA)

urine

62

●

●

●

●

●

TVB

DeJesus

2-Methylhippuric acid (2MHA)

urine

62

●

●

●

●

●

TVB

DeJesus

3- & 4-Methylhippuric acid (34MH)

urine

62

●

●

●

●

●

TVB

DeJesus

t,t-Muconic acid (MUCA)

urine

62

WD

WD

WD

●

●

TVB

DeJesus

Phenylglyoxylic acid (PHGA)

urine

62

●

●

●

●

●

TVB

DeJesus

2-Thioxothiazolidine-4-carboxylic acid (TTCA)

urine

62

●

●

WD

WD

●

TVB

DeJesus

N -Acetyl-S-(2-hydroxy-2-methyl-3-buten-1-yl)-Lcysteine (IPM2) + N-Acetyl-S-(2-hydroxy-3-methyl-3buten-1-yl)-L-cysteine (IPM1)

urine

62

WD

●

WD

d

TVB

DeJesus

urine

62

●

●

●

TVB

DeJesus

urine

62

TVB

DeJesus

N-Acetyl-S-(3-hydroxypropyl-1-methyl)-L-cysteine
(HPMM)
N-Acetyl-S- (1-hydroxymethyl-2-propenyl)-L-cysteine
(MHB1)

N-Acetyl-S-(4-hydroxy-2-methyl-2-buten-1-yl)-Lcysteine (IPMA3)
N-Acetyl-S(((4-[Methylsulfinyl]butyl)
amino)thioxomethyl)-L-cysteine (SUMA)

09-10

WD

Page 18 of 18

19-20

●