Laboratory Assessment 2025-2026 and Earlier

Attachment_8_Lab_Assessments_2025-2026 and earlier_2024JULY16.docx

[NCHS] National Health and Nutrition Examination Survey (NHANES)

Laboratory Assessment 2025-2026 and Earlier

OMB: 0920-0950

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Attachment 8



Laboratory Assessment 2025-2026 and Earlier



Attachment 8: Laboratory Assessment 2025-2026 and Earlier

NCEH MASTER LIST OF ANALYTES TABLE LEGEND

 

Empty cell indicates that the analyte was not measured or reported to NCHS during that cycle

●

Measured during cycle and reported to NCHS via data file submission, or measurement is planned for future NHANES survey

P

Sample was pooled during cycle

Surplus

Measurement of analyte originally planned for regular NHANES but later converted to surplus sample request during cycle, per NCHS

& Surplus

Table data published in exposure report as regular sample and as surplus sample (updated data, children only data, etc.)

NO PRBC

No Packed Red Blood Cells (PRBC) available during cycle

C

Measuring is contingent upon funding and other resources during cycle

X1

Measured but not reported, as MECs were contaminated with those analytes

WD

Analyte/chemical originally intended to be measured and withdrawn during cycle; please follow up with branch for description

D

Dropped during cycle/cycled out; unless otherwise stated, most common reason is no detection

DEV

Method in development during cycle

Strikethrough

Analyte methodology discontinued/dropped for methods issues; included in table for archival purposes

x

Was not approved by NCHS

♀

Female

♂

Male

{Analyte} Isomer

Refer to one of the isomer associated with specified analyte

Analyte/Chemical/Metabolite

Measured Matrix

Sample Cycle
< 21-23

Sample Cycle

> 25-26

11-12

13-14

15-16

17-18

19-20

21-23

25-26

Formaldehyde

PRBC

Full set, then 1/3

Full set, then 1/2

 

●

●

D

D

D

 

Acrylamide

NO PRBC

●

●

D

D

D

 

Glycidamide

●

●

D

D

D

 

Ethylene Oxide

 

●

●

●

●

D

 

Acrylonitrile

1/3 of 6+

1/2 of 5+

 

 

 

 

 

●

 

Sex Steroid Hormones (Reproductive Hormones)

 

 

 

 

 

 

 

 

 

Estradiol, Total (E2)

Serum

Proposed 6+, only this Analyte 2–4

Proposed: 5+ , only this Analyte 2-4

 

●

●

Surplus

●

●

 

Steroid Hormone–Binding Globulin (SHBG)

 

●

●

Surplus

●

●

 

Testosterone, Total (TT)

●

●

●

x

●

●

 

17α-Hydroxyprogesterone (17-OHP) / Hydroxyprogesterone

 

 

 

Surplus

●

●

 

Progesterone (P4)

 

 

 

Surplus

●

●

 

Estrone (E1)

 

 

 

Surplus

●

●

 

Estrone sulfate (E1S)

 

 

 

Surplus

●

●

 

Androstenedione (AD)

 

 

 

Surplus

●

●

 

Dehydroepiandrosterone sulfate (DHEAS)

 

 

 

x

●

●

 

Anti-Müllerian hormone (AMH)

♀ 6+

,♀ 5+

 

 

 

Surplus

●

●

 

Follicle-stimulating hormone (FSH)

6+

5+

 

 

 

Surplus

●

●

 

Luteinizing hormone (LH)

 

 

 

Surplus

●

●

 

Trans Fatty Acids

 

 

 

 

 

 

 

 

 

 

 

trans-9-Hexadecenoic acid

Plasma

1/3 of 3+

1/2 of 3+

D

 

 

 

 

●

 

trans-9-Octadecenoic acid

D

 

 

 

 

●

 

trans,trans-9,12-Octadecadienoic acid

D

 

 

 

 

●

 

trans-11-Octadecanoic acid

D

 

 

 

 

●

 

Thyroid Function

 

 

 

 

 

 

 

 

 

 

 

Free thyroxine (FT4)

Serum

N/A

TBA

 

 

 

 

 

 

●

Total thyroxine (TF4)

 

 

 

 

 

 

●

Thyroid peroxidase antibodies







●

Thyroglobulin antibodies

 

 

 

 

 

 

●

Thyroid-stimulating hormone (TSH)

 

 

 

 

 

 

●

(TSH) receptor antibodies

 

 

 

 

 

 

●

Thyroglobulin *

 

 

 

 

 

 

C

Free T3 * -Triiodothyronine

 

 

 

 

 

 

C

Total T3 * -Triiodothyronine

 

 

 

 

 

 

●

Fructose (CT)

 

 

 

 

 

 

●

Cholinesterase Assays in Blood and Serum

 

 

 

 

 

 

 

RBC Acetylcholinesterase activity (AChE activity)

Whole Blood

Full Set, 6+

Full Set, 5+

 

 

 

 

x

●

 

Butyrylcholinesterase activity (BChE activity)

Serum

 

 

 

 

 

●

●

Butyrylcholinesterase concentration (BChE)

 

 

 

 

 

●

●

Chlorinated Tyrosines

 

 

 

 

 

 

 

Serum 3-chlorotyrosine

Serum

6+

5+

 

 

●

 

x

 

 

Serum 3,5-dichlorotyrosine

 

 

●

 

 

 

 

Metals and Metalloids

 

 

 

 

 

 

 

Antimony

 

Urine

3–5 & 1/3 of 6+

3–4 & 1/2 of 5+

●

●

●

●

●

●

●

Arsenic (total)

 

●

●

●

●

●

●

●

Arsenic (V) acid

 

●

●

●

●

●

●

●

Arsenobetaine

 

●

●

●

●

●

●

●

Arsenocholine

 

●

●

●

●

●

●

●

Arsenous (III) acid

 

●

●

●

●

●

●

●

Dimethylarsinic acid

 

●

●

●

●

●

●

●

Monomethylarsonic acid

 

●

●

●

●

●

●

●

Trimethylarsine oxide

 

●

D

 

 

 

 

 

Barium

 

●

●

●

●

●

●

●

Beryllium

 

D

 

 

 

 

 

 

Cadmium

 

Whole Blood

Full; 1/2 (13–14)

1+

●

●

●

●

●

●

 

Cadmium

 

Urine

3–5 & 1/3 of 6+

3-4 & 1/2 of 5+

●

●

●

●

●

●

●

Cesium

 

●

●

●

●

●

●

●

Chromium

 

 

 

 

●

●

●

●

Chromium

 

Whole Blood

40+

1+

 

 

●

●

D

 

 

Cobalt

 

 

 

 

 

●

●

D

 

 

Cobalt

 

Urine

3–5 & 1/3 of 6+

3–4 & 1/2 of 5+

●

●

●

●

●

●

●

Copper

 

Serum

1/3 of 12+

1/2 of 12+

●

●

●

D

 

 

 

Lead

 

Urine

3–5 & 1/3 of 6+

3–4 & 1/2 of 5+

●

●

●

●

●

●

●

Lead

 

Whole Blood

Full; 1/2 (13–14)

Full; 1+

●

●

●

●

●

●

●

Manganese

 

Full; 1/2 (13–14)

1+

●

●

●

●

●

●

●

Manganese

 

Urine

3–5 & 1/3 of 6+

3-4 & 1/2 5+

●

●

●

●

●

●

 

Mercury (total)

 

Whole Blood

Full; 1/2 (13–14)

1+

●

●

●

●

●

●

●

Mercury (inorganic)

Urine

 

 

●

●

●

●

●

●

●

Mercury (ethyl)

 


 

 

●

●

●

●

●

●

●

Mercury (methyl)

 

 

 

●

●

●

●

●

●

●

Mercury

 

3–5 & 1/3 of 6+

3-4 & 1/2 of 5+

●

●

●

●

●

●

●

Molybdenum

 

 

 

●

●

●

●

●

●

●

Nickel

 

 

 

 

 

 

●

●

●

●

Platinum

 

 

 

D

 

 

 

 

 

 

Selenium

 

Whole Blood

Full; 1/2 (13–14)

Full; 1/2 (13-14)

●

●

●

●

●

●

●

Selenium

 

Serum

1/3 of 12+

1/2 of 12+

●

●

●

D

 

 

 

Strontium

 

Urine

3–5 & 1/3 of 6+

3–4 & 1/2 of 5+

●

●

●

●

●

●

●

Thallium

 

 

 

●

●

●

●

●

●

●

Tin

 

 

 

●

●

●

●

●

●

●

Tungsten

 

 

 

●

●

●

●

●

●

●

Uranium

 

 

 

●

●

●

●

●

●

 

Zinc

 

Serum

1/3 of 12+

1/2 of 12+

●

●

●

D

 

 

 

Iodine

 

Urine

3–5 & 1/3 of 6+

3–4 & 1/2 of 5+

●

●

●

●

●

●

●

Iodine

 

Salt

 

 

 

 

 

 

●

D

 

Iodine

 

Salt

 

 

 

 

 

 

●

D

 

Fluoride

 

Water

0–19 & MEC examined

0–17 & MEC examined

 

 

 

 

●

D

 

Fluoride

 

Urine

6-19

5-19

 

●

●

D

 

 

 

Caffeine and Metabolites

 

 

 

 

 

 

 

 

 

 

 

5-acetylamino-6-amino-3-methyluracil

Urine

6+

N/A

●

●

D

 

 

 

 

1-methyluric acid

●

●

D

 

 

 

 

3-methyluric acid

●

●

D

 

 

 

 

7-methyluric acid

●

●

D

 

 

 

 

1,3-dimethyluric acid

●

●

D

 

 

 

 

1,7-dimethyluric acid

●

●

D

 

 

 

 

3,7-dimethyluric acid

●

●

D

 

 

 

 

1,3,7-trimethyluric acid

 


●

●

D

 

 

 

 

1-methylxanthine

 

●

●

D

 

 

 

 

3-methylxanthine


●

●

D

 

 

 

 

7-methylxanthine

●

●

D

 

 

 

 

1,3-dimethylxanthine (theophylline)

●

●

D

 

 

 

 

1,7-dimethylxanthine (paraxanthine)

●

●

D

 

 

 

 

3,7-dimethylxanthine (theobromine)

●

●

D

 

 

 

 

1,3,7-trimethylxanthine (caffeine)

 


●

●

D

 

 

 

 

Fatty acids (30)

 

 

 

 

 

 

 

 

 

 

 

Capric acid (C10:0)

 

Plasma /Serum

NH11–14 3+ & 12+ fasting

N/A

●

●

D

 

 

 

 

Lauric acid (C12:0)

 

●

●

D

 

 

 

 

Myristic acid (14:0)

 

●

●

D

 

 

 

 

Pentadecanoic acid (C15:0)

 

●

●

D

 

 

 

 

Palmitic acid (16:0)

 

●

●

D

 

 

 

 

Margaric acid (C17:0)

 

●

●

D

 

 

 

 

Stearic acid (18:0)

 

●

●

D

 

 

 

 

Arachidic acid (20:0)

 

●

●

D

 

 

 

 

Docosanoic acid (22:0)

 

●

●

D

 

 

 

 

Tricosanoic acid (C23:0)

 

●

●

D

 

 

 

 

Lignoceric acid (24:0)

 

●

●

D

 

 

 

 

Myristoleic acid (14:1n-5)

 

●

●

D

 

 

 

 

Palmitoleic acid (16:1n-7)

 

●

●

D

 

 

 

 

cis-Vaccenic acid (18:1n-7)

 

●

●

D

 

 

 

 

Oleic acid (18:1n-9)

 

●

●

D

 

 

 

 

Eicosenoic acid (20:1n-9)

 

●

●

D

 

 

 

 

Docosenoic acid (22:1n-9)

 

D

 

 

 

 

 

 

Nervonic acid (24:1n-9)

 

●

●

D

 

 

 

 

Linoleic acid (18:2n-6)

 

●

●

D

 

 

 

 

alpha-Linolenic acid (18:3n-3)

 

●

●

D

 

 

 

 

gamma-Linolenic acid (18:3n-6)

 

●

●

D

 

 

 

 

Stearidonic acid (C18:4n-3)

 

●

●

D

 

 

 

 

Eicosadienoic acid (20:2n-6)


●

●

D

 

 

 

 

homo-gamma-Linolenic acid (20:3n-6)

●

●

D

 

 

 

 

Eicosatrienoic acid (C20:3n-9)

●

●

D

 

 

 

 

Arachidonic acid (20:4n-6)

●

●

D

 

 

 

 

Eicosapentaenoic acid (20:5n-3)

●

●

D

 

 

 

 

Docosatetraenoic acid (22:4n-6)

●

●

D

 

 

 

 

Docosapentaenoic acid (22:5n-3)

●

●

D

 

 

 

 

Docosapentaenoic acid (22:5n-6)

●

●

D

 

 

 

 

Docosahexaenoic acid (22:6n-3)

●

●

D

 

 

 

 

Fatty acids in RBCs (NBB)

 

 

 

 

 

 

 

 

% alpha-Linolenic acid (C18:3n3)

RBC

6+

5+





●

●


% Arachidic acid (C20:0)




 

 

 

 

●

●

 

% Arachidonic acid (C20:4n6)








●

●


% Docosanoic acid (C22:0)




 

 

 

 

●

●

 

% Docosahexaenoic acid (C22:6n3)




 

 

 

 

●

●

 

% Docosapentaenoic acid 3 (C22:5n3)








●

●


% Docosapentaenoic acid 6 (C22:5n6)








●

●


% Docosatetraenoic acid (C22:4n6)








●

●


% Docosatetraenoic acid (C22:4n6)








●

●


% 11-Eicosenoic acid (C20:1n9)




 

 

 

 

●

●

 

% Eicosapentaenoic acid (C20:5n3)








●

●


% gamma-Linolenic acid (C18:3n6)




 

 

 

 

●

●

 

% homo-gamma-Linolenic acid (C20:3n6)

 




 

 

 

 

●

●

 

% Tetracosanoic acid (C24:0)

 




 

 

 

 

●

●

 

% Linoleic acid (C18:2n6)

 




 

 

 

 

●

●

 

% Myristic acid (C14:0)

 




 

 

 

 

●

●

 

% 15-Tetracosenoic acid (C24:1n9)




 

 

 

 

●

●

 

% Oleic acid (C18:1n9)

 




 

 

 

 

●

●

 

% Palmitoleic acid (C16:1n7)




 

 

 

 

●

●

 

% Palmitic acid (C16:0)

 




 

 

 

 

●

●

 

% Stearic acid (C18:0)




 

 

 

 

●

●

 

Fat-Soluble Vitamins and Micronutrients

 

 

 

 

 

 

 

Vitamin A

 

Serum

NH17–18: 6+

5+

 

 

 

●

D

C

 

Vitamin E

 

N/A

 

 

 

●

D

 

 

Retinyl palmitate

 

 

 

 

●

D

 

 

Retinyl stearate

 

 

 

 

●

D

 

 

Gamma-Tocopherol


 

 

 

●

D

 

 

delta-Tocopherol

 

 

 

 

 

 

 

alpha-carotene

 

 

 

●

D

 

 

Trans-beta-carotene

 


 

 

 

●

D

 

 

Cis-beta-carotene

 

 

 

 

●

D

 

 

alpha-Cryptoxanthin


 

 

 

●

D

 

 

beta-Cryptoxanthin

 

 

 

●

D

 

 

Lutein/zeaxanthin combined or measured and reported as separate analytes

 

 

 

●

D

 

 

trans-Lycopene

 


 

 

 

●

D

 

 

Total lycopene


 

 

 

●

D

 

 

25-OH Vitamin D (D2 + D3)

 


5+

●

●

●

●

D

C

 

25-OH Vitamin D2

 

●

●

●

●

D

C

 

25-OH Vitamin D3

 

●

●

●

●

D

C

 

epimer-25-OH Vitamin D3

 

●

●

●

●

D

C

 

Iron-Status and Inflammation Indicators

 

 

 

 

 

 

Ferritin

 

Serum

NH03–16: 1–5 & ♀ 12–49 NH17–20: 1–5 & 12+

1-5 & 12+

D

 

Surplus

Surplus

●

C

 

Transferrin receptor


NH03–16: 1–5 & ♀ 12–49 NH17–18: 1–5 & 12+ NH19–20: 1–5y & ♀ 12–49

1-5 & ♀ 12-49

D

 

●

●

●

C

 

Alpha-acid-1-glycoprotein

NH15–18: 1–5 & ♀ 12–49

 

 

●

●

 

C

 

Iron

 


1/3

1/2

 

 

 

 

 

 

 

TIBC

 

 

 

 

 

 

 

 

Transferrin saturation


 

 

 

 

 

 

 

Protoporphyrin

 


 

 

 

 

 

 

 

Phytoestrogens and Metabolites

 

 

 

 

 

 

 

Daidzein

 

Urine

6+

N/A

D

 

 

 

 

 

 

Enterodiol

 

D

 

 

 

 

 

 

Enterolactone


D

 

 

 

 

 

 

Equol

 


D

 

 

 

 

 

 

Genistein

 

D

 

 

 

 

 

 

O-Desmethylangolensin


D

 

 

 

 

 

 

Water-Soluble Vitamins and Related Compounds

 

 

 

 

 

 

 

 

Folate (Serum)

Serum

1+

N/A

D

 

 

 

 

 

 

Folate (RBC)

RBC

NH11–16: 1+ NH17–20: ♀ 12–49; 1/2 (♂ 1+, ♀ 1–11 & 50+)

♀ 12–49 ; 1/2 (♂ 1+, ♀ 1–11 & 50+)

●

●

●

●

●

C

 

Total folate (calculated)

●

●

●

●

●

C

 

5-Methyltetrahydrofolate

 

●

●

●

●

●

C

 

Folic acid

 

●

●

●

●

●

C

 

5-Formyltetrahydrofolate

 

●

●

●

●

●

C

 

Tetrahydrofolate

 

●

●

●

●

●

C

 

5,10-Methenyltetrahydrofolate

 

●

●

●

●

●

C

 

MeFox oxidation product

 

●

●

●

●

●

C

 

Folate forms by LC-MS/MS

Serum

1/3

1/2

 

 

 

 

 

 

 

Folate forms by LC-MS/MS (RBC)

 

1/3

 

 

 

 

 

 

 

Total folate (calculated)

RBC

NH19–20: 6+

5+

 

 

 

 

●

C

 

5-Methyltetrahydrofolate

 

 

 

 

●

C

 

Folic acid

 

 

 

 

●

C

 

5-Formyltetrahydrofolate

 

 

 

 

●

C

 

Ttrahydrofolate

 

 

 

 

●

C

 

5,10-Methenyltetrahydrofolate

 

 

 

 

●

C

 

MeFox oxidation product

 

 

 

 

●

C

 

Homocysteine

Plasma

20+

N/A

 

 

 

 

 

 

 

Methylmalonic acid

Plasma/ Serum

3+

5+

●

●

D

 

 

 

 ●

Vitamin B12

Serum

20+

●

●

D

 

 

 

 ●

Vitamin B6 (pyridoxal-5'-phosphate)

1+

D

 

 

 

 

 

 ●

Vitamin B6 (4-pyridoxic acid)


D

 

 

 

 

 

 ●

Vitamin C (ascorbic acid)

NH17–18: 6+


 

 

 

●

D

C

 

Vitamin D


 

 

 

 

 

 

 

Personal Care and Consumer Product Chemicals and Metabolites

 

 

 

 

 

 

 

Benzophenone-3

Urine

1/3

3–4 & 1/2 of 5+

●

●

●

●

●

●

 

Bisphenol A

●

●

●

●

●

●

 

Bisphenol F

 

●

●

●

●

●

 

Bisphenol S

 

●

●

●

●

●

 

Triclocarban

 

●

●

●

●

●

 

4-tert-Octyl phenol

D

 

 

 

 

 

 

Triclosan

●

●

●

●

●

●

 

Butyl paraben

●

●

●

●

●

●

 

Hydroxy Butyl paraben

 

 

 

Surplus

●

●

 

Ethyl paraben

●

●

●

●

●

●

 

Methyl paraben

●

●

●

●

●

●

 

n-Propyl paraben

●

●

●

●

●

●

 

Di-hydroxy avobenzone

 

 

 

Surplus

●

●

 

2,4-Dichlorophenol

●

●

●

●

●

●

 

2,5-Dichlorophenol

●

●

●

●

●

●

 

Flame-Retardant Metabolites

 

 

 

 

 

 

 

 

 

 

 

Bis(1-chloro-2-propyl) phosphate (BCPP)

Urine

1/3

3–4 & 1/2 of 5+

Surplus

Surplus

 

Surplus

●

●

 

Bis(2-chloroethyl) phosphate (BCEtP)

 

 

 

Surplus

●

●

 

Bis(1,3-dichloro-2-propyl) phosphate (BDCPP)

 

 

 

Surplus

●

●

 

Dibenzyl phosphate (DBzP)

 

 

 

Surplus

D

 

 

Dibutyl phosphate (DBuP)

 

 

 

Surplus

●

●

 

Di-o-cresylphosphate (DoCP)

 

 

 

 

 

 

 

Di-p-cresylphosphate (DpCP)

 

 

 

 

 

 

 

Di-cresyl phosphate (DCP)

Surplus

 

Surplus

D

D

 

 

Diphenyl phosphate (DPhP)

 

Surplus

Surplus

Surplus

●

●

 

2,3,4,5-Tetrabromobenzoic acid (TBBA)

 

Surplus

Surplus

Surplus

●

●

 

2-((isopropyl)phenyl) phenyl phosphate (iPPPP)

 

 

Surplus

Surplus

 

●

 

4-((tert-butyl)phenyl)phenyl phosphate (tBPPP)

 

 

Surplus

Surplus

 

●

 

Bis(2-butoxyethyl) phosphate (BBOEP)

1/2

 

 

 

 

 

 

●

Bis(2-butoxyethyl) 2-hydroxyethyl phosphate (BBOEHEP)

 

 

 

 

 

 

●

Bis(2-butoxyethyl) [(3-hydroxybutyl)oxy]ethyl phosphate (3HO-TBOEP)

 

 

 

 

 

 

●

2-ethylhexyl phenyl phosphate (EHPHP)

 

 

 

 

 

 

●

2-ethyl-5-hydroxyhexyl diphenyl phosphate (5HO-EHDPP)

 

 

 

 

 

 

●

1-hydroxy-2-propyl bis(1-chloro-2-propyl) phosphate (BCIPHIPP)

 

 

 

 

 

 

●

Tris(2-chloroethyl)phosphate (TCEtP)

 

 

 

 

 

 

●

Dibutyl 3-Hydroxybutyl Phosphate (3HO-TBuP)

 

 

 

 

 

 

●

Di isobutyl phosphate (DiBuP)

 

 

 

 

 

 

●

4-Hydroxyphenyl diphenyl phosphate (4HO-DPhP)

 

 

 

 

 

 

●

2-(2-Methylphenoxy)-4H-1,3,2-benzodioxaphosphorin 2-oxide (CBDP)

 

 

 

 

 

 

●

Fungicides and Metabolites (OAT)

 

 

 

 

 

 

 

 

ortho-Phenylphenol

 

Urine

 

 

D

 

 

 

 

 

 

Ethylenethio Urea (ETU)

 

 

 

 

 

 

 

 

 

 

Pentachlorophenol

 

 

 

 

 

 

 

 

 

 

Propylenethio Urea (PTU)

 

 

 

 

 

 

 

 

 

 

Herbicides and Metabolites

Atrazine

 

Urine

1/3

1/2

 

 

 

 

 

 

 

Atrazine mercapturate

 

 

 

 

 

 

 

 

Desethyl atrazine

 

 

 

 

 

 

 

 

Desisopropyl atrazine


 

 

 

 

 

 

 

Desisopropyl atrazine mercapturate

 


 

 

 

 

 

 

 

Diaminochloroatrazine

 

 

 

 

 

 

 

 

2,4-Dichlorophenoxyacetic acid

 

●

●

●

●

●

●

 

2,4,5-Trichlorophenoxyacetic acid


D

 

 

 

 

 

 

Desethyl atrazine mercapturate

 


 

 

 

 

 

 

 

N-(phosphonomethyl)glycine (Glyphosate)

 

 

& Surplus

Surplus

  Surplus

 

●

 

N-Acetyl-AMPA

 

 

 

 

Surplus

 

●

 

N-Acetyl-glyphosate

 

 

 

 

 

 

●

 

Aminomethlphosphonic acid (AMPA)

 

 

Surplus

Surplus

 

 

D

 

Dicamba (3,6-dichloro-2-methoxybenzoic acid)

 

 

 

 

 

 

●

 

3,6 Dichlorosalicylic acid (dicamba metabolite)

 

 

 

 

 

 

●

 

Glufosinate (Phosphinothricin; (RS)-2-Amino-4-(hydroxy(methyl)phosphonoyl)butanoic acid)

 

 

 

 

 

 

●

 

N-Acetyl-glufosinate (N-acetylphosphinothricin)

 

 

 

 

 

 

●

 

3-(Methylphosphinico)propionic acid (glufosinate metabolite)

 

 

 

 

 

 

●

 

Sulfonyl Urea Herbicides (Herbicides: Substituted Ureas)

 

 

 

 

 

 

 

Bensulfuron-methyl

 

Urine

1/3

1/2

 

 

 

 

 

 

 

Chlorsulfuron

 

 

 

 

 

 

 

 

Ethametsulfuron-methyl

 

 

 

 

 

 

 

 

Foramsulfuron

 

 

 

 

 

 

 

 

Halosulfuron

 

 

 

 

 

 

 

 

Mesosulfuron-methyl

 

 

 

 

 

 

 

 

Metsulfuron-methyl

 

 

 

 

 

 

 

 

Nicosulfuron

 

 

 

 

 

 

 

 

Oxasulfuron

 

 

 

 

 

 

 

 

Primisulfuron-methyl

 

 

 

 

 

 

 

 

Prosulfuron

 

 

 

 

 

 

 

 

Rimsulfuron

 

 

 

 

 

 

 

 

Sulfometuron-methyl

 

 

 

 

 

 

 

 

Sulfosulfuron

 

 

 

 

 

 

 

 

Thifensulfuron-methyl

 

 

 

 

 

 

 

 

Triasulfuron

 

 

 

 

 

 

 

 

Triflusulfuron-methyl

 

 

 

 

 

 

 

 

Insect Repellent and Metabolites

 

 

 

 

 

 

 

 

N,N-Diethyl-meta-toluamide (DEET)

 

Urine

1/3

1/2

●

●

D

 

 

 

 

3-(Diethylcarbamoyl) benzoic acid (DEET acid/DCBA)


●

●

●

●

●

●

 

3-(Ethylcarbamoyl) benzoic acid (MEA/ECBA)

 


 

 

Surplus

●

●

●

 

N,N-Diethyl-3-(hydroxymethyl) benzamide (Desethyl hydroxy DEET/DHMB)


●

●

D

 

 

 

 

Neonicotinoid Insecticides

 

 

 

 

 

 

 

 

 

 

Acetamiprid (ACET)

Urine

1/3

1/2

 

 

Surplus

Surplus

●

D

 

Clothianidin (CLOT)

 


 

 

 

 

●

●

 

N-Desmethylacetamiprid (AND)


 

 

 

 

●

●

 

5-Hydroxyimidacloprid (OHIM)

 


 

 

 

 

●

●

 

Imidacloprid (IMID)

 

 

 

 

 

●

D

 

Thiacloprid (THIA)

 

 

 

 

 

●

D

 

Clothianidin Desmethyl (CLOD)

 

 

 

 

 

 

●

 

Clothianidin Urea (CLOU)


 

 

 

 

 

●

 

Flupyradifurone (FLUP)

 


 

 

 

 

 

●

 

Imidacloprid Guanidine (IMIG)

 

 

 

 

 

 

●

 

Nitenpyram Desmethyl (NITD)

 

 

 

 

 

 

●

 

Thiamethoxam Desmethyl (TMXD)

 

 

 

 

 

 

●

 

Sulfoxaflor 1 (SLF1)

 

 

 

 

 

 

●

 

Sulfoxaflor 2 (SLF2)

 

 

 

 

 

 

 

 

●

 

Carbamate Pesticide Metabolites

 

 

 

 

 

 

 

Carbofuranphenol

Urine

1/3

1/2

 

 

 

 

 

 

 

2-Isopropoxyphenol

 

 

 

 

 

 

 

Organophosphorus Insecticides: Dialkyl Phosphate Metabolites

 

 

 

 

 

 

Diethylphosphate (DEP)

 

Urine

1/3

1/2

●

D

●

●

●

●

 

Dimethylphosphate (DMP)


●

D

●

●

●

●

 

Diethylthiophosphate (DETP)

●

D

●

●

●

●

 

Dimethylthiophosphate (DMTP)

 


●

D

●

●

●

●

 

Diethyldithiophosphate (DEDTP)

 

●

D

●

●

●

●

 

Dimethyldithiophosphate (DMDTP)

 

●

D

●

●

●

●

 

Organophosphorus Insecticides: Specific Metabolites

Acephate

 

Urine

1/3

1/2

 

 

 

 

 

 

 

Dimethoate

 

 

 

 

 

 

 

 

Methamidaphos

 

 

 

 

 

 

 

 

Omethoate

 

 

 

 

 

 

 

 

Malathion dicarboxylic acid

 

●

●

●

●

●

D

 

2-Isopropyl-4-methyl-6-hydroxypyrimidine (IMPY)


●

●

●

●

●

●

 

para-Nitrophenol

 


●

●

●

●

●

●

 

3,5,6-Trichloro-2-pyridinol (TCPy)

 

●

●

●

●

●

●

 

2-diethylamino-6-methyl pyrimidin-4-ol

 

 

 

 

 

 

 

 

Pyrethroid Metabolites

 

 

 

 

 

 

 

 

trans-3-(2,2-Dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid (trans-DCCA)

 

Urine

44929

44928

●

●

●

●

●

●

 

cis-3-(2,2-Dibromovinyl)-2,2-dimethylcyclopropane carboxylic acid (cis-DBCA)

 

 

 

●

●

●

●

●

D

 

4-Fluoro-3-phenoxybenzoic acid (4F3PBA)

 

 

 

●

●

●

●

●

D

 

3-Phenoxybenzoic acid (3PBA)

 

 

 

●

●

●

●

●

●

 

cis-3-(2,2-Dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid (cis-DCCA)

 

 

 

 

 

 

 

 

 

 

Organochlorine Pesticides and Metabolites

 

 

 

 

 

 

Aldrin

 

Serum

1/3

1/2

 

 

 

 

 

 

 

Dieldrin

 

 

 

 

 

 

 

 

Endrin

 

 

 

 

 

 

 

 

Heptachlor Epoxide


 

 

 

 

 

 

 

Oxychlordane

 


P

P

P

●

●

●

 

trans-Nonachlor

 

P

P

P

●

●

●

 

p,p'-DDT

 

P

P

P

●

●

●

 

p,p'-DDE

 

P

P

P

●

●

●

 

o,p'-DDT

 

 

 

 

 

 

 

 

Hexachlorobenzene


P

P

P

●

●

●

 

beta-Hexachlorocyclohexane

 


P

P

P

●

●

●

 

gamma-Hexachlorocyclohexane

 

P

D

 

 

 

 

 

Mirex

 

P

P

P

●

●

●

 

2,4,5-Trichlorophenol

 

Urine

D

 

 

 

 

 

 

2,4,6-Trichlorophenol

 

D

 

 

 

 

 

 

Polybrominated Diphenyl Ethers and Brominated Biphenyl 153

 

 

 

 

 

2,2',4’-Tribromodiphenyl ether (BDE 17)

 

Serum

1/3

1/2

P

P

P

●

●

●

 

2,4,4’-Tribromodiphenyl ether (BDE 28)


P

P

P

●

●

●

 

2,2’,4,4’-Tetrabromodiphenyl ether (BDE 47)

 


P

P

P

●

●

●

 

2,3',4,4'-Tetrabromodiphenyl ether (BDE 66)

 

P

P

P

 

 

 

 

2,2’,3,4,4’-Pentabromodiphenyl ether (BDE 85)

 

P

P

P

●

●

●

 

2,2’,4,4’,5-Pentabromodiphenyl ether (BDE 99)


P

P

P

●

●

●

 

2,2’,4,4’,6-Pentabromodiphenyl ether (BDE 100)

P

P

P

●

●

●

 

2,2’,4,4’,5,5’-Hexabromodiphenyl ether (BDE 153)

 


P

P

P

●

●

●

 

2,2’,4,4’,5,6’-Hexabromodiphenyl ether (BDE 154)

 

P

P

P

●

●

●

 

2,2’,3,4,4’,5’,6-Heptabromodiphenyl ether (BDE 183)

 

P

P

P

●

●

●

 

2,2',3,3',4,4',5,5',6,6'-Decabromodiphenyl ether (BDE 209)

 

P

P

P

●

●

●

 

2,2’,4,4’,5,5’-Hexabromobiphenyl (PBB 153)

 

P

P

P

●

●

●

 

Polychlorinated Dibenzo-p-dioxins

 

 

 

 

 

 

1,2,3,4,6,7,8-Heptachlorodibenzo-p-dioxin (HpCDD)

Serum

1/3

1/2

P

P

P

●

●

●

 

1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin (HxCDD)

P

P

P

●

●

●

 

1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin (HxCDD)

P

P

P

●

●

●

 

1,2,3,7,8,9-Hexachlorodibenzo-p-dioxin (HxCDD)

P

P

P

●

●

●

 

1,2,3,4,6,7,8,9-Octachlorodibenzo-p-dioxin (OCDD)

P

P

P

●

●

●

 

1,2,3,7,8-Pentachlorodibenzo-p-dioxin (PeCDD)

P

P

P

●

●

●

 

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) 

 


P

P

P

●

●

●

 

Polychlorinated Dibenzofurans

 

 

 

 

 

 

 

 

1,2,3,4,6,7,8-Heptachlorodibenzofuran (HpCDF) 

Serum

1/3

1/2

P

P

P

●

●

●

 

1,2,3,4,7,8,9-Heptachlorodibenzofuran (HpCDF)

P

P

P

●

●

●

 

1,2,3,4,7,8-Hexachlorodibenzofuran (HxCDF)

 

P

P

P

●

●

●

 

1,2,3,6,7,8-Hexachlorodibenzofuran (HxCDF)

P

P

P

●

●

●

 

1,2,3,7,8,9-Hexachlorodibenzofuran (HxCDF)

 

P

P

P

●

●

●

 

2,3,4,6,7,8-Hexachlorodibenzofuran (HxCDF)

 

P

P

P

●

●

●

 

1,2,3,4,6,7,8,9-Octachlorodibenzofuran (OCDF)

 

P

P

P

●

●

●

 

1,2,3,7,8-Pentachlorodibenzofuran (PeCDF)

 

P

P

P

●

●

●

 

2,3,4,7,8-Pentachlorodibenzofuran (PeCDF)

 

P

P

P

●

●

●

 

2,3,7,8-Tetrachlorodibenzofuran (TCDF)

P

P

P

●

●

●

 

Dioxin-like Polychlorinated Biphenyls: Coplanar PCBs

 

 

 

 

 

 

 

 

3,4,4',5-Tetrachlorobiphenyl (PCB 81)

Serum

1/3

1/2

P

P

P

●

●

●

 

3,3',4,4',5-Pentachlorobiphenyl (PCB 126)

P

P

P

●

●

●

 

3,3',4,4',5,5'-Hexachlorobiphenyl (PCB 169)

P

P

P

●

●

●

 

Dioxin-like Polychlorinated Biphenyls: Mono-ortho-Substituted PCBs

2,3,3',4,4'-Pentachlorobiphenyl (PCB 105)

 

Serum

1/3

1/2

P

P

P

●

●

●

 

2,3,3',4,4'-Pentachlorobiphenyl (PCB 114)

P

P

P

●

●

●

 

2,3',4,4',5-Pentachlorobiphenyl (PCB 118)

 

P

P

P

●

●

●

 

2',3,4,4',5-Pentachlorobiphenyl (PCB 123)

 

 

 

 

 

 

 

 

2,3,3',4,4',5-Hexachlorobiphenyl (PCB 156)

 

P

P

P

●

●

●

 

2,3,3',4,4',5'-Hexachlorobiphenyl (PCB 157)

P

P

P

●

●

●

 

2,3',4,4',5,5'-Hexachlorobiphenyl (PCB 167)

 

P

P

P

●

●

●

 

2,3,3’,4,4’,5,5’-Heptachlorobiphenyl (PCB 189)

 

P

P

P

●

●

●

 

Polychlorinated Biphenyls: Non-Dioxin-Like

 

 

 

 

 

 

 

2,4,4'-Trichlorobiphenyl (PCB 28)

 

Serum

1/3

1/2

P

P

P

●

●

●

 

2,2'3,5'-Tetrachloro biphenyl (PCB 44)

 

 

 

 

 

 

 

2,2',4,5'-Tetrachloro biphenyl (PCB 49)

 

 

 

 

 

 

 

 

2,2',5,5'-Tetrachlorobiphenyl (PCB 52)

 

 

 

 

 

 

 

 

2,3',4,4'-Tetrachlorobiphenyl (PCB 66)

P

P

P

●

●

●

 

2,4,4',5-Tetrachlorobiphenyl (PCB 74)

 

P

P

P

●

●

●

 

2,2’,3,4,5’-Pentachlorobiphenyl (PCB 87)

 

 

 

 

 

 

 

2,2',4,4',5-Pentachlorobiphenyl (PCB 99)

 

P

P

P

●

●

●

 

2,2',4,5,5'-Pentachlorobiphenyl (PCB 101)

 

 

 

 

 

 

 

 

2,3,3’,4’,6-Pentachlorobiphenyl (PCB 110)

 

 

 

 

 

 

 

2,2',3,3',4,4'-Hexachlorobiphenyl (PCB 128)

 

 

 

 

 

 

 

2,2',3,4,4',5' and 2,3,3’,4,4’,6-Hexachlorobiphenyl (PCB 138 & 158)

P

P

P

●

●

●

 

2,2',3,4',5,5'-Hexachlorobiphenyl (PCB 146)

 

P

P

P

●

●

●

 

2,2’,3,4’,5’,6-Hexachlorobiphenyl (PCB 149)

 

 

 

 

 

 

 

2,2’,3,5,5’,6-Hexachlorobiphenyl (PCB 151)

 

 

 

 

 

 

 

 

2,2',4,4',5,5'-Hexachlorobiphenyl (PCB 153)

 

P

P

P

●

●

●

 

2,2',3,3',4,4',5-Heptachlorobiphenyl (PCB 170)

 

P

P

P

●

●

●

 

2,2',3,3',4,5,5'-Heptachlorobiphenyl (PCB 172)

 

 

 

 

 

 

 

2,2',3,3',4,5',6'-Heptachlorobiphenyl (PCB 177)

 

 

 

 

 

 

 

 

2,2',3,3',5,5',6-Heptachlorobiphenyl (PCB 178)

P

P

P

●

●

●

 

2,2',3,4,4',5,5'-Heptachlorobiphenyl (PCB 180)

P

P

P

●

●

●

 

2,2',3,4,4',5',6-Heptachlorobiphenyl (PCB 183)

P

P

P

●

●

●

 

2,2',3,4',5,5',6-Heptachlorobiphenyl (PCB 187)

 

P

P

P

●

●

●

 

2,2’,3,3’,4,4’,5,5’-Octachlorobiphenyl (PCB 194)

 

P

P

P

●

●

●

 

2,2’,3,3’,4,4’,5,6-Octachlorobiphenyl (PCB 195)

 

 

 

 

 

 

●

 

2,2’,3,3’,4,4’,5,6’ and 2,2’,3,4,4’,5,5’,6-Octachlorobiphenyl (PCB 196 & 203)

P

P

P

●

●

●

 

2,2’,3,3’,4,5,5’,6-Octachlorobiphenyl (PCB 199)

P

P

P

●

●

●

 

2,2’,3,3’,4,4’,5,5’,6-Nonachlorobiphenyl (PCB 206)

 


P

P

P

●

●

●

 

2,2',3,3',4,4',5,5',6,6'-Decachloro biphenyl (PCB 209)

 

P

P

P

●

●

●

 

Perfluoroalkyl and Polyfluoroalkyl Substances: Surfactants

Perfluorobutane sulfonic acid (PFBS)

 

Serum

1/3

1/2

●

& Surplus

D

 

 

 

 

Pefluorodecanoic acid (PFDA)


●

& Surplus

●

●

●

●

 

Perflurododecanoic acid (PFDoA)

●

& Surplus

●

D

 

 

 

Perfluoroheptanoic acid (PFHpA)

 


●

& Surplus

D

 

 

 

 

Perfluorohexane sulfonic acid (PFHxS)


●

& Surplus

●

●

●

●

 

Perfluorononanoic acid (PFNA)

 


●

& Surplus

●

●

●

●

 

Perfluorooctanoic acid (PFOA)


●

& Surplus

 

 

 

 

 

n-Perfluorooctanoic acid (n-PFOA)

 

& Surplus

●

●

●

●

 

Branched Perfluorooctanoic acid isomers (Sb-PFOA)*

 

Surplus

●

●

●

●

 

Perfluorooctane sulfonic acid (PFOS)

●

●

 

 

 

 

 

n-Perfluorooctane sulfonic (n-PFOS)

 


 

● Surplus

●

●

●

●

 

Perfluoromethylheptane sulfonic acid isomers (Sm-PFOS)*


 

 

●

●

●

●

 

Perfluorooctane sulfonamide (PFOSA or FOSA)

 


●

 

 

 

 

 

 

Perfluoroheptanesulfooic acid (PFHpS)

 

 

 

 

& Surplus

D

 

 

Perfluorohexanoic acid (PFHxA)

 

 

 

 

Surplus

D

 

 

9-Chlorohexadecafluoro-3-oxanonane-1-sulfonic acid (9Cl-PF3ONS)


 

 

 

 

D

 

 

Adona (4,8-dioxa-3H-perfluorononanoic acid) (ADONA)

 

 

 

 

D

 

 

GenX ( 2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)-propanoic acid (HFPO-DA))

 

 

 

 

D

 

 

2-(N-Ethyl-perfluorooctane sulfonamido) acetic acid (EtFOSAA)

●

Surplus

 

 

 

 

 

2-(N-Methyl-perfluorooctane sulfonamido) acetic acid (MeFOSAA)

●

 

●

●

●

●

 

Perfluoroundecanoic acid (PFUA or PFUnDA)

●

 

●

●

●

●

 

Perfluoroalkyl and Polyfluoroalkyl Substances: Urine

Perfluorobutanoic acid (PFBA)

Urine

1/3

1/2

 

& Surplus

 

Surplus

D

 

 

PFBS

 

 

 

 

 

 

 

 

 

 

PFDA

 

 

 

 

 

 

 

 

 

 

Perfluoroheptane sulfonic acid (PFHpS)

1/3

1/2

 

 

 

Surplus

D

●

 

PFHpA

 

 

 

 

 

 

 

 

 

 

PFHxS

 

 

 

 

 

 

 

 

 

 

Perfluorohexanoic acid (PFHxA)

1/3

1/2

 

 

 

Surplus

D

●

 

PFNA

 

 

 

 

 

 

 

 

 

 

n-PFOA

 

 

 

 

 

 

 

 

 

 

Sb-PFOA

 

 

 

 

 

 

 

 

 

 

n-PFOS

 

 

 

 

 

 

 

 

 

 

Sm-PFOS

 

 

 

 

 

 

 

 

 

 

Perfluoropentanoic acid (PFPeA)

1/3

1/2

 

 

 

Surplus

D

 

 

PFUnDA

 

 

 

 

 

 

 

 

 

 

9-Chlorohexadecafluoro-3-oxanonane-1-sulfonic acid (9Cl-PF3ONS)

1/3

1/2

 

 

 

Surplus

D

 

 

Adona (4,8-dioxa-3H-perfluorononanoic acid) (ADONA)

 

 

 

 

 

Surplus

D

 

 

GenX ( 2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)-propanoic acid (HFPO-DA))

 

 

 

 

 

Surplus

D

 

 

Phthalate and Phthalate Alternative Metabolites

Mono-benzyl phthalate (MBzP)

 

Urine

1/3

1/2

●

●

●

●

●

●

 

Mono-2-hydroxybutyl phthalate (MHBP)

 

Surplus

●

●

●

●

 

Mono-n-butyl phthalate (MnBP)

 

●

●

●

●

●

●

 

Mono-iso-butyl phthalate (MiBP)

●

●

●

●

●

●

 

Mono-2-hydroxyisobutyl phthalate (MHiBP)

 

Urine

 

& Surplus

& Surplus

& Surplus

●

●

 

Mono-cyclohexyl phthalate (MCHP)

 

D

 

 

 

 

 

 

Mono-ethyl phthalate (MEP)

 

●

●

●

●

●

●

 

Mono-2-ethylhexyl phthalate (MEHP)

●

●

●

●

●

●

 

Mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP)

 

●

●

●

●

●

●

 

Mono-(2-ethyl-5-oxohexyl) phthalate (MEOHP)

●

●

●

●

●

●

 

Mono-(2-ethyl-5-carboxypentyl) phthalate (MECPP)

 

●

●

●

●

●

●

 

Mono-carboxyisononyl phthalate (MCNP)

 

●

●

●

●

●

●

 

Mono-oxoisodecyl phthalate (MODP)

 

 

WD

WD

D

 

 

Mono-isononyl phthalate (MiNP)

●

●

●

●

D

 

 

Mono-oxoisononyl phthalate (MONP)

 

 

 

& Surplus

& Surplus

●

●

 

Mono-carboxyisoctyl phthalate (MCOP)

●

●

●

●

●

●

 

Mono-methyl phthalate (MMP)

 

●

D

 

 

 

 

 

Mono-(3-carboxypropyl) phthalate (MCPP)

●

●

●

●

●

●

 

Mono-n-octyl phthalate (MOP)

 

D

 

 

 

 

 

 

Cyclohexane 1,2-dicarboxylic acid mono hydroxy isononyl ester (MHNCH®)

●

●

●

●

●

●

 

Cyclohexane-1,2-dicarboxylic acid-mono(carboxyoctyl) ester (MCOCH)

 

 

WD

●

●

●

●

 

Mono (2-ethyl-5-carboxypentyl) terephthalate (MECPTP)

 

 

& Surplus

& Surplus

●

●

 

Mono (2-ethyl-5-hydroxyhexyl) terephthalate (MEHHTP)

 

 

& Surplus

& Surplus

●

●

 

Polycyclic Aromatic Hydrocarbon Metabolites

 

 

 

 

 

2-Hydroxyfluorene

Urine

1/3

1/2

●

●

●

●

●

●

 

3-Hydroxyfluorene

●

●

●

●

●

●

 

9-Hydroxyfluorene

●

D

 

 

 

 

 

1-Hydroxyphenanthrene 

●

●

●

●

●

●

 

2-Hydroxyphenanthrene

●

D

 

 

 

 

 

3-Hydroxyphenanthrene

●

D

 

 

 

 

 

2- & 3-Hydroxyphenanthrene

 

●

●

●

●

●

 

4-Hydroxyphenanthrene

●

D

 

 

 

 

 

1-Hydroxypyrene

●

●

●

●

●

●

 

1-Hydroxynapthalene (1-Naphthol)

●

●

●

●

●

●

 

2-Hydroxynapthalene (2-Naphthol)

●

●

●

●

●

●

 

Phenylpyrazole insecticides (fipronil)

Fipronil ((RS)-5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl)pyrazole-3-carbonitrile)

Urine

1/3

1/2

 

 

Surplus

Surplus

 

●

 

Fipronil desulfinyl

 

 

Surplus

Surplus

 

●

 

Fipronil Sulfone

 

 

Surplus

Surplus

 

●

 

Fipronil Carboxamide

 

 

Surplus

Surplus

 

●

 

Fipronil Sulfide

 

 

Surplus

Surplus

 

●

 

Hydroxy Fipronil

 


 

 

Surplus

Surplus

 

●

 

Tobacco Alkaloids and Metabolites (Cotinine and Nicotine Analogs)

 

 

 

 

 

 

 

Anabasine, Total

 

Urine

3–5 & 1/3 of 6+

3–4 & 1/2 of 5+

 

●

●

●

●

●

 

Anatabine, Total


 

●

●

●

●

●

 

Cotinine

Serum

3+

2+

●

●

●

●

●

●

 

Cotinine, Total

 

Urine

3–5 & 1/3 of 6+

3–4 & 1/2 of 5+

 

●

●

●

●

●

 

Cotinine N-Oxide, Total


 

●

●

●

●

●

 

trans-3'-Hydroxycotinine, Total

Serum

3+

2+

 

●

●

●

●

●

 

trans-3'-Hydroxycotinine, Total

Urine

3–5 & 1/3 of 6+

3–4 & 1/2 of 5+

 

●

●

●

●

●

 

Norcotinine

 


 

●

●

WD

WD

D

 

1-(3-Pyridyl)-1-butanol-4-carboxylic acid


 

WD

●

●

●

●

 

Nicotine

 


 

●

●

●

●

●

 

Nicotine 1'-Oxide, Total


 

●

●

●

●

●

 

Nornicotine

 


 

●

●

●

●

●

 

Tobacco Biomarkers: Tobacco-specific Nitrosamines (TSNAs)

 

 

 

 

 

 

 

N'-Nitrosoanabasine (NAB)

Urine

3–5 & 1/3 of 6+

3–4 & 1/2 of 5+

 

●

WD

WD

WD

WD

 

N'-Nitrosoanatabine (NAT)

 

●

WD

WD

WD

WD

 

N'-Nitrosonornicotine (NNN)

 

●

WD

WD

WD

WD

 

4-(Methylnitrosamino)-1-(3-pyridyl)-1-Butanol (NNAL)

●

●

●

●

●

●

 

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

 

WD

WD

WD

WD

WD

 

Tobacco Biomarkers: Volatile N-Nitrosamines

 

 

 

 

 

 

N-Nitrosodiethylamine (NDEA)

Urine

1/3

1/2

 

●

WD

D

D

D

 

N-nitrosodimethylamine (NDMA)

 

WD

WD

D

D

D

 

N-Nitrosoethylmethylamine (NMEA)

 

●

WD

D

D

D

 

N-nitrosomorpholine (NMOR)

 

●

WD

D

D

D

 

N-Nitrosopiperidine (NPIP)

 

●

WD

D

D

D

 

N-Nitrosopyrrolidine (NPYR)

 

●

WD

D

D

D

 

Disinfection Byproducts - Volatile Organic Compounds (VOCs) - Trihalomethanes & MTBE (IN WATER)

 

 

 

 

Bromodichloromethane

Water

1/3

1/2

D

 

 

 

 

 

 

Dibromochloromethane (Chlorodibromomethane)

D

 

 

 

 

 

 

Tribromomethane (Bromoform)

D

 

 

 

 

 

 

Trichloromethane (Chloroform)

D

 

 

 

 

 

 

Methyl tert-butyl ether (MTBE)

D

 

 

 

 

 

 

Disinfection Byproducts - Volatile Organic Compounds (VOCs) - Trihalomethanes & MTBE

 

Bromodichloromethane

Whole Blood

1/2 of 12+

1/2 of 12+

●

●

●

●

●

●

 

Dibromochloromethane (Chlorodibromomethane)

●

●

●

●

●

●

 

Tribromomethane (Bromoform)

●

●

●

●

●

●

 

Trichloromethane (Chloroform)

●

●

●

●

●

●

 

Perchlorate and Other Anions

 

Nitrate

 

Urine

1/3

1/2

●

●

●

●

●

●

 

Perchlorate

 

 

 

●

●

●

●

●

●

 

Thiocyanate

 

 

 

●

●

●

●

●

●

 

Perchlorate

 

Water

1/3

1/2

 

 

 

 

 

 

 

Nitrate

 

 

 

 

 

 

 

 

 

 

Fluoride

 

Urine

 

 

 

 

WD

WD

D

 

 

Iodide

 

Water

 

 

 

 

 

 

 

 

 

Tobacco Biomarkers: Heterocyclic Amines

 

 

 

 

3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1)

Urine

1/3

1/2

 

●

D

WD

WD

D

 

2-Amino-3-methyl-9H-pyriodo[2,3-b]indole (MeA-α-C)

 

●

D

WD

WD

D

 

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

 

●

D

WD

WD

D

 

2-Amino-9H-pyrido[2,3-b]indole (A-α-C)

 

●

D

WD

WD

D

 

2-Amino-3-methyl-3H-imidazo[4,5-f]quinolone (IQ)


●

D

WD

WD

D


2-Amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole (Glu-P1)

 

●

D

WD

WD

D

 

2-Aminodipyrido[1,2-a:3',2'-d] imidazole (Glu-P2)


●

D

WD

WD

D


1-Methyl-9H-pyrido[3,4-]indole (Harman)

 

 

●

D

WD

WD

D

 

1-Methyl-3-amino-5H-pyrido[4,3-b]indole (Trp-P-2)

 

●

D

WD

WD

D

 

9H-Pyrido[3,4-]indole (Norharman)

 

 

●

D

WD

WD

D

 

Volatile Organic Compounds (VOCs)

 

 

 

 

 

 

 

1,1,1-Trichloroethane (Methyl chloroform)

Whole Blood

1/2 of 12+

1/2 of 12+

●

●

●

●

●

●

●

1,1,1,2-Tetrachloroethane

●

●

●

●

●

D

 

1,1,2,2-Tetrachloroethane

●

D

 

 

 

 

 

1,1,2-Trichloroethane

●

D

 

 

 

 

 

1,2,3-Trichloropropane

●

●

●

●

●

●

●

1,1-Dichloroethane

●

D

 

 

 

 

 

1,1-Dichloroethene (Vinylidene chloride)

●

D

 

 

 

 

 

1,2-Dibromo-3-chloropropane (DBCP)

D

 

 

 

 

 

 

1,2-Dibromoethane

 


●

●

●

●

●

D

 

1,2-Dichlorobenzene

 

●

●

●

●

●

●

●

1,2-Dichloroethane (Ethylene dichloride)

 

●

●

●

●

●

●

●

cis-1,2-Dichloroethene

 

●

D

 

 

 

 

 

trans--1,2-Dichloroethylene

 

●

D

 

 

 

 

 

1,2-Dichloropropane

Whole Blood

●

D

 

 

 

 

 

1,3-Dichlorobenzene

 

●

●

●

●

●

●

●

1,4-Dichlorobenzene (p-Dichlorobenzene)

 

●

●

●

●

●

●

●

1,4-Dioxane

 

●

●

●

WD

D

 

 

1-Bromopropane/Propyl bromide

 

WD

D

 

 

 

 

2,5-Dimethylfuran

 

●

●

●

●

●

●

●

2-Hexanone

 

 

 

 

 

WD

●

●

Benzene

 

●

●

●

●

●

●

●

Benzonitrile

 

 

WD

●

●

●

●

●

Chlorobenzene (Monochlorobenzene)

●

●

●

●

●

●

●

Chloroethane

 

 

●

●

●

●

●

●

Cyclohexane

 

 

●

●

●

●

●

●

Dibromomethane

 

●

D

 

 

 

 

 

Dichloromethane (Methylene chloride)

●

●

●

●

●

●

●

Diethyl ether

 

●

●

●

●

●

●

Ethyl acetate

 

 

●

●

●

●

●

●

Ethylbenzene

 

●

●

●

●

●

●

●

Furan

 

●

●

●

●

●

●

●

n-Heptane

 

 

●

●

●

●

●

●

Hexachloroethane

 

●

D

 

 

 

 

 

n-Hexane

 

●

●

●

●

●

●

●

Isobutyronitrile

 

 

WD

●

●

●

●

●

Isopropylbenzene (Cumene)

 

●

●

●

●

●

●

●

Methyl tert-butyl ether (MTBE)

●

●

●

●

●

●

●

Methylcyclopentane

 


 

●

●

●

●

●

●

Methyl isobutyl ketone

 

 

WD

WD

●

●

●

●

Nitrobenzene

 

●

●

●

●

●

D

 

Nitromethane

 

●

D

 

 

 

 

 

n-Octane

 

 

●

●

●

●

●

●

Styrene

Whole Blood

X1

X1

X1

X1

X1

●

●

Tetrachloroethene (Perchloroethylene)

●

●

●

●

●

●

●

Tetrachloromethane (Carbon tetrachloride)

●

●

●

●

●

●

●

Tetrahydrofuran

 

 

●

●

●

●

●

●

Toluene

X1

●

●

X1

X1

●

●

Trichloroethene (Trichloroethylene)

●

●

●

●

●

●

●

α,α,α-Trifluorotoluene

 

●

●

●

●

D

 

Vinyl bromide

 

 

●

●

●

●

D

 

m-/p-Xylene

 

●

●

●

●

●

●

●

o-Xylene

●

●

●

●

●

●

●

α-Pinene

 

 

 

 

●

●

●

Volatile Organic Compound Metabolites (VOC metabolites)

N-Acetyl-S- (2-carboxyethyl)-L-cysteine (CEMA)

Urine

1/3

3–4 & 1/2 of 5+

●

●

●

●

●

●

●

N-Acetyl-S- (3-hydroxypropyl)-L-cysteine (HPMA)

 

●

●

●

●

●

●

●

N-Acetyl-S-(2-carbamoylethyl)-L-cysteine (AAMA)

 

●

●

●

●

●

●

●

N-Acetyl-S-(2-carbamoyl-2-hydroxyethyl)-L-cysteine (GAMA)

●

●

●

●

●

●

●

N-Acetyl-S-(1-cyano-2-hydroxyethyl)-L-cysteine

 

 

●

●

●

●

●

N-Acetyl-S-(2-cyanoethyl)-L-cysteine (CYMA)

●

●

●

●

●

●

●

N-Acetyl-S- (2-hydroxyethyl)-L-cysteine (HEMA)

●

●

●

●

●

●

●

N-Acetyl-S-(phenyl)-L-cysteine (PMA)

●

●

●

D

 

N-Acetyl-S-(n-propyl)-L-cysteine (BPMA)

●

●

●

●

●

●

●

N-Acetyl-S- (3,4-dihydroxybutyl)-L-cysteine (DHBM)

●

●

●

●

●

●

●

N-Acetyl-S- (1-hydroxymethyl-2-propenyl)-L-cysteine (MHB1)

●

●

●

D

 

 

 

N-Acetyl-S- (2-hydroxy-3-butenyl)-L-cysteine (MHB2)

●

●

●

D

 

 

 

N-Acetyl-S-(2-hydroxy-3-methyl-3-buten-1-yl)-L-cysteine + N-Acetyl-S-[1-(hydroxymethyl)-2-methyl-2-propen-1-yl]-L-cysteine

 

WD

●

D

 

 

 

N-Acetyl-S- (4-hydroxy-2-butenyl)-L-cysteine (MHB3)

●

●

●

●

●

●

●

N-Acetyl-S-(4-hydroxy-2-methyl-2 buten-1-yl)-L-cysteine

 

 

●

●

●

●

●

2-Thioxothiazolidine-4-carboxylic acid (TTCA)

●

●

WD

●

●

●

●

N-Acetyl-S-(3-hydroxypropyl-1-methyl)-L-cysteine (HPMM)

 

Urine

●

●

●

●

●

●

●

2-Aminothiazoline-4-carboxylic acid (ATCA)

 

●

●

●

●

●

●

●

N-Acetyl-S-(N-methylcarbamoyl)-L-cysteine (AMCA)

 

●

●

●

●

●

●

●

Phenylglyoxylic acid (PHGA)

 

●

●

●

●

●

●

●

N-Acetyl-S- (2-hydroxypropyl)-L-cysteine (HPM2)

●

●

●

●

●

●

●

N-Acetyl-S-(1-phenyl-2-hydroxyethyl)-L-cysteine + N-Acetyl-S-(2-phenyl-2-hydroxyethyl)-L-cysteine (PHEM)

●

●

●

●

●

●

●

Mandelic acid (MADA)

 

●

●

●

●

●

●

●

N-Acetyl-S-(trichlorovinyl)-L-cysteine (TCVM)

 

●

●

●

D

 

 

 

N-Acetyl-S-(benzyl)-L-cysteine (BMA)

●

●

●

●

●

●

●

N-Acetyl-S-(1,2-dichlorovinyl)-L-cysteine (1DCV)

 

●

●

●

D

 

 

 

N-Acetyl-S-(2,2-dichlorovinyl)-L-cysteine (2DCV)

●

●

●

D

 

 

 

N-Acetyl-S-(dimethylphenyl)-L-cysteine (DPMA)

●

●

●

D

 

 

 

2-Methylhippuric acid (2MHA)

●

●

●

●

●

●

●

3- & 4-Methylhippuric acid (34MH)

●

●

●

●

●

●

●

MMA N-Acetyl-S-methyl-L-cysteine

3–4, 1/2 of 5+

 

 

 

 

 

 

●

PPMA N-Acetyl-S-(6-hydroxy-2,4-cyclohexadiene-1-yl)-L-cysteine)

 

 

 

 

 

 

●

t,t-Muconic acid (MUCA)

1/3

1/2

WD

WD

WD

D

N-Acetyl-S(((4-[Methylsulfinyl]butyl) amino)thioxomethyl)-L-cysteine (SUMA)

 

 

 

 

 

 

 

Aldehydes

 

 

 

 

 

 

 

 

 

 

 

Acetaldehyde

Serum

1/3 of smokers

1/2 of smokers

 

 

D

 

 

 

 

Acrolein

 

 

 

D

 

 

 

 

Benzaldehyde

 

 

●

D

 

 

 

 

Butyraldehyde

 

 

●

D

 

 

 

 

Crotonaldehyde

 

 

●

D

 

 

 

 

Decanaldehyde

 

 

●

D

 

 

 

 

Furaldehyde

 

 

 

D

 

 

 

 

Heptanaldehyde

 

 

●

D

 

 

 

 

Hexanaldehyde

 

 

●

D

 

 

 

 

Isobutyraldehyde

 

 

D

 

 

 

 

Isopentanaldehyde

 

●

D

 

 

 

 

Nonanaldehyde

 

 

●

D

 

 

 

 

Octanaldehyde

 

 

●

D

 

 

 

 

Pentanaldehyde

 

 

●

D

 

 

 

 

Propanaldehyde

 

 

●

D

 

 

 

 

o-Tolualdehyde

 

 

●

D

 

 

 

 

trans-Hexanal

 

 

 

D

 

 

 

 

trans-Octenal

 

 

 

D

 

 

 

 

trans-Nonenal

 

 

 

D

 

 

 

 

Tobacco Biomarkers: Aromatic Amines (TVB)

 

 

 

 

 

 

 

 

 

4-Aminobiphenyl

Urine

1/3

1/2

 

●

WD

WD

WD

D

 

1-Aminonaphthalene

 

 

WD

WD

WD

D

 

2-Aminonaphthalene

 

●

WD

WD

WD

D

 

o-Anisidine

 

●

WD

WD

WD

D

 

2,6-Dimethylaniline

 

●

WD

WD

WD

D

 

o-Toluidine

 

●

WD

WD

WD

D

 

Quinoline

Urine

1/3

1/2

 

WD

WD

WD

WD

D

 

Urinary Aromatic Diamines (formerly Diisocyanate metabolites and urinary amines)

4,4'-Diaminodiphenylmethane (4MDA)

Urine

 

 

Surplus

 

●

D

 

 

 

1,5-Diaminonaphthalene (5NDA)

 

 

 

 

●

D

 

 

 

2,4-Diaminotoluene (4TDA)

 

 

 

 

●

D

 

 

 

2,6-Diaminotoluene (6TDA)

 

 

 

 

●

D

 

 

 

p-Phenylenediamine (PPDA)

 

 

 

 

●

D

 

 

 

o-Phenylenediamine (OPDA)

 

 

Surplus

 

WD

D

 

 

 

5-Amino-1,3,3-trimethylcyclohexanemethylamine (IPDA)

 

 

 

 

WD

●

●

 

 

Hexamethylenediamine (HAD)

 

 

 

 

WD

●

●

 

 

β-N-Methylamino-L-alanine (BMAA)

 

 

 

 

WD

●

●

 

 

Trimethylamine N-oxide (TMAO)

 

 

 

 

WD

●

●

 

 

Benzene Metabolites (VOC metabolites II)

 

N-2-Furoylglycine (N2FG)

Urine

1/3

1/2

 

 

 

Surplus

 

●

 

5-Hydroxymethyl-2-furancarboxylic acid (HMFA)

 

 

 

Surplus

 

●

 

2,5-Furandicarboxylic acid (FDCA)

 

 

 

Surplus

 

 

 

5-Hydroxymethyl-2-furoylglycine (HMFG)

 

 

 

Surplus

 

●

 

N-Acetyl-S-(phenyl)-L-cysteine (PMA/PHMA)

3–4 & 1/2 of 5+

 

 

 

Surplus

●

●

●

t,t-Muconic acid (MUCA)/Muconic acid (MUCA)

 

 

 

Surplus

●

●

●

5-Hydroxy-N-methyl-2-pyrrolidone (5HMP)

 

 

 

WD

 

 

 

Terpenes in Serum (Terpenes)

α-Pinene (SAPN)

Serum

1/2 of 5+

1/2 of 5+

 

Surplus

 

 

 

●

●

β-Pinene (SBPN)

 

 

 

 

 

●

●

β-Myrcene (SBMY)

 

Surplus

 

 

 

●

 

Δ-3-Carene (SD3C)

 

 

 

 

 

●

 

d-Limonene (SLIM)

 

Surplus

 

 

 

●

●

β-Caryophyllene (SBCP)

 

Surplus

 

 

 

●

 

α-Humulene (SAHU)

 

WD

 

 

 

●

 




8-16


File Typeapplication/vnd.openxmlformats-officedocument.wordprocessingml.document
AuthorTouarti, Christina
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File Created2024-10-28
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