GARLRN Performance Measure Tool

Thank you for completing the Global Antimicrobial Resistance (AR) Laboratory and Response Network (Global AR Lab & Response Network) Performance Measurement (PM) tool. This tool is intended to establish and collect standardized process and outcome metrics for recipients implementing Global AR Lab & Response Network projects. Recipients will be asked to complete this tool annually, in addition to the required Cooperative Agreement annual performance and progress reporting.

Please complete the tool using information that will be included in your organization's Year 3 performance narrative submission. Please answer as many questions as possible.

If you need any assistance, please contact [email protected].

Shape3

Public reporting burden of this collection of information is estimated to average 5 hours per response per year, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the collection of information. An agency may not conduct or sponsor, and a person is not required to respond to a collection of information unless it displays a currently valid OMB control number. Send comments regarding this burden estimate or any other aspect of this collection of information, including suggestions for reducing this burden to CDC/ATSDR Reports Clearance Officer; 1600 Clifton Road NE, MS D-74, Atlanta, Georgia 30333; Attn: OMB-PRA (0920-1282).

****Please complete the following forms based on project activities implemented during budget period 3 (BP3).

FORM 1: RECIPIENT INFORMATION

This form is to be completed at recipient level. Please complete based on project activities during the current budget period BP4. If any recipients are implementing multiple projects, they will be asked to kindly complete Sections 1-3 of this form for each additional Strategy 2-5 projects.
For any questions where recipient is not aware or unsure of response, please enter ‘N/A’ or ‘Unknown’ where applicable

Name of Recipient Organization:

Recipient HQ location:

Please select the the option that best describes this organization (select all that apply):

Non-governmental Organization (NGO)
Government Organization
Academic Institution
Other (Please specify):

Funded Strategy(s): (Select all that apply)

Strategy 2: Assess Antimicrobial Resistance in Enteric Pathogens
Strategy 3: Assess Antimicrobial Resistance in Fungal Pathogens
Strategy 4: Assess Antimicrobial Resistance in Invasive Bacterial and Respiratory Pathogens
Strategy 5: Assess Antimicrobial Resistance in N. gonorrhoeae

Please select the pathogen(s) of interest for this project: (select all that apply)

Carbapenem-resistant Acinetobacter
Candida auris
Clostridioides difficile
Carbapenem-resistant Enterobacterales
Drug-resistant Neisseria gonorrhoeae
Drug-resistant Campylobacter
Drug-resistant Candida
ESBL-producing Enterobacteriaceae
Haemophilus influenzae
Vancomycin-resistant Enterococci
Multidrug-resistant Pseudomonas aeruginosa
Drug-resistant nontyphoidal Salmonella
Drug-resistant Salmonella serotype Typhi
Drug-resistant Shigella
Methicillin-resistant Staphylococcus aureus
Neisseria meningitidis
Drug-resistant Streptococcus pneumoniae
Drug-resistant Tuberculosis
Erythromycin-resistant group A Streptococcus
Clindamycin-resistant group B Streptococcus
Azole-resistant Aspergillus fumigatus
Drug-resistant Bordetella pertussis
Other (please specify as many as needed):

SECTION 1: PROJECT IMPLEMENTATION

Please answer the following questions about this organization’s experiences with project implementation¹. Please use information that will be included in this organization's Year 3 performance narrative submission.

PROJECT IMPLEMENTATION
Q ID	Question	Answer options	Notes
1.	How many countries is this project being implemented in during BP4?	Integer


1.a.	Please select the countries in which this project was implemented during BP3. (select all that apply)	Check boxes for all CK 2104 Strategies 2-5 countries
1.i.	What is the number of sites (laboratories, hospitals, healthcare facilities, etc.) that were supported as part of the project? Please answer for each country.	Integer	Follow up question for each country selected in 1.a.
1.i.
1.ii.	How many sites received direct material support (i.e., lab reagents/diagnostics, other lab equipment, IT material, printed SOPs, etc.) from this organization during this budget period as part of the project? Please answer for each country.	Integer	Follow up question for each country selected in 1.a.


2.	Is this project contributing to achieving the goals of a country’s national action plan (NAP) on antimicrobial resistance?	Yes, in all countries where project is implemented. ( 2.a/b.)
		Yes, in some countries ( 2.a/b.)
		c) No ( 2.c.)
		d) Don’t Know
		e) Does not apply/No NAP has been developed in any target country(s)
	2.a./b.	If yes, please list all countries and describe supporting activities of NAP (Open-ended) List as follows: 1. [Country A Name], [supporting activities of NAP]; 2. [Country B Name], [supporting activities of NAP]; 3. [Country C Name], [supporting activities of NAP]; etc
	2.c.	If no, please list barriers to participation and/or support of the NAP (Open-ended)
3.	List any major product(s) (e.g., SOPs, job aids, manuscripts, posters, trainings, etc.) developed within this budget period. If none, enter N/A	Open ended
4.	Have any CDC Subject Matter Experts (SMEs) reviewed² the major products listed in question #5?	Yes
		No ( 4.b.)
		Don’t Know
		Does not apply
	4.b.	If no, please explain (Open ended)
5.	What strategies or activities has [pilot_recipname] implemented to address sustainability of the efforts and progress made with this project beyond the current budget period?	Open ended
	Please use this space to include any additional information related to implementation of this project.	Open ended

SECTION 2: LABORATORY ACTIVITIES

Please answer the following questions based on this organization’s current laboratory enhancement activities for this Global AR Lab & Response Network project. Please use information that will be included in this organization’s Year 3 performance narrative submission and please be as thorough as possible.

LABORATORY ACTIVITIES
Q ID	Question	Answer options	Notes
1.	Is there a national or central laboratory³ which performs external quality assurance (EQA) to subnational labs for this project?	a) Yes ( 1.a.)
		No
		Don’t know
		Doesn’t apply
	1.a. If yes, please:	i. List the number of labs that External Quality Assessment (EQA) was provided to, by country (Open ended)
	1.a. If yes, please:	ii. Describe the EQA (pathogens included, number of isolates or samples submitted, and frequency), by country. (Open ended)
2.-6. During the current budget period, has this organization provided training or support to any laboratories in the following areas? (Yes/No)  If yes, section will expand with follow up questions
2.	CULTURING	a) What is the total number of labs where training or other activities for performing culturing were implemented. (Integer - Enter 999 if unknown)
3.	PHENOTYPIC TESTING	a) What is the total number of labs where training or other activities for performing phenotypic testing were implemented. (Integer - Enter 999 if unknown)
4.	GENOTYPIC TESTING	a) What is the total number of labs where training or other activities for performing genotypic testing were implemented. (Integer - Enter 999 if unknown)
5.	ANTIMICROBIAL SUSCEPTIBILITY TESTING (AST), INCLUDING ANTIFUNGAL SUSCEPTIBILITY TESTING (AFST)	What is the total number of labs where training or other activities for performing antimicrobial susceptibility testing (AST) were implemented?
		(Integer - Enter 999 if unknown)
6.	WHOLE GENOME SEQUENCING (WGS)	What is the total number of labs at which training or other activities for performing whole genome sequencing (WGS) were implemented?
	WHOLE GENOME SEQUENCING (WGS)	(Integer - Enter 999 if unknown)
	Please use this space to include any additional information related to this organization's laboratory activities.	Open ended

SECTION 3: WORKFORCE DEVELOPMENT ACTIVITIES

The following questions cover current education and training activities for different personnel targeted by this Global AR Lab & Response Network project. Do not answer questions based on future efforts, only established or current opportunities during budget period 3.

WORKFORCE DEVELOPMENT ACTIVITIES
Q ID	Question	Answer options	Notes
Personnel Types	Please select the type of personnel that received training from this organization (can be in collaboration with partners): (select all that apply)	Laboratory
Personnel Types		Epidemiologist/Data Manager
		Healthcare Worker
		Field-based personnel (community interviewer)
		MOH/NPHL leadership
		Other (please specify): _________________ Trainings that were performed did not document types of personnel in attendance (please provide disaggregated number of personnel) No personnel received training during this budget period ( end of form)
1.-5. For each personnel type selected above, please answer the following:
1.	How many CDC-supported⁴ education and training opportunities have targeted [insert personnel type] personnel?	(Open ended)


2.	Are there any other partnerships (e.g., universities, hospitals, etc.) that provide mentorship for [insert personnel type] personnel targeted by this project?	a) Yes ( 2.a.)
		No
		Don’t Know
	2.a.	If yes, please list these partnerships. (Open ended)
3.	How many [insert personnel type] personnel received training?	(Open ended)
4.	Has a training curriculum been established for training [insert personnel type] personnel?	a) Yes ( 4.a.)
		No
	4.a. If yes,	i. Does the curriculum leverage a Train-the-Trainer model? (Yes/No)
		ii. What entity is responsible for facilitating the curriculum? (Open ended)
		iii. What assessments were conducted to ensure trainings addressed knowledge gaps? (Open ended)
	Please use this space to include any additional information about this organization’s workforce development activities related to this project.

-----------------------------------------------END OF FORM 1 ---------------------------------------------------------------

FORM 2: PROJECT IMPLEMENTATION AND REFERRAL NETWORK/SURVEILLANCE ACTIVITIES

The following questions are related to project implementation with partners as well as referral network and surveillance practices at EACH hospital, health care facility (HCF) and/or laboratory that is participating in [name of organization autofill]'s Global AR Lab & Response Network project.

Please complete FORM 2 for EACH partner, HCF/hospital, anor laboratory. Recipients with projects in multiple countries or engaged with multiple partners or HCFS/hospitals/laboratories will be asked to specify country and partner/facility name on each form.

Partner or Laboratory Site Information

Partner Name*:

We are defining the term “partners” broadly to include partners that this organization regularly collaborates with or engages as part of the activities for this project. This can include national and sub-national level government ministries; individual healthcare facilities, hospitals and/or individual laboratories; academic partners; other non-governmental organizations (NGOs); etc.).

Examples: Country X MoH; Local hospital or HCF; Private laboratory; etc.

Is this partner a laboratory or healthcare facility with lab?

i. Yes ( Complete entire form for this site)

ii. No ( Respond to “**Alternative 2” & STOP once Section 1 is complete)

Select the option that best describes the level of the health system that the laboratory or healthcare facility site supports:
1. National level
2. Regional, state or provincial level
3. District or local level
4. Other (Please specify): ________________________

2.a. Is this lab or healthcare site part of an academic institution? Y/N

2.b. Is this lab or healthcare site part of a private organization? Y/N

**Alternative 2. Select the option that best describes this partner: (If No selected above)

Government ministry (national or sub-national)
Private Industry
Academic Institution
NGO
Other (Please specify): ________________________

Name of partner’s location:

Name of country: – country drop down menu

Project contribution(s) made by this partner⁵ (e.g., equipment and supplies procured, trainings provided, isolates collected and submitted, etc.):

SECTION 1: PROJECT IMPLEMENTATION PHASE

Q ID	Question	Answer options	Notes
6.	Select the phase that best describes this partner’s and/or site’s implementation, for the current reporting period:	Exploration – Engaging stakeholders to identify 1. need(s); and 2. appropriate steps to address gaps or enhance activities
		Initiation – Project planning; consensus reached with stakeholders regarding project sites, objectives, and activities, as well as timeline for implementation
		Initial Implementation – Beginning stages of project implementation at selected sites including: 1. collection of baseline data; 2. establishing new practices/protocols; 3. supply/equipment procurement; 4. recruitment/hiring of locally based staff; etc.
		Full Implementation and Maintenance – Majority of project activities have been rolled out and routinely monitored
		Expansion/Scale-Up – Increasing the number of sites targeted for project activities
		Reduction/Scale Down – Decreasing the number of sites targeted for project activities or scaling down scope of activities
	Please use this space to provide any additional context or information about project implementation phase with this partner.	Open ended

SECTION 2: LABORATORY NETWORK ACTIVITIES

The following questions cover current laboratory and/or referral network activities at the project site. This section is only completed for laboratories or HCFs with lab. Recipients will complete this section for each individual laboratory or HCF with lab site where project is being implemented. Do not answer questions based on future efforts, only established or current activities. Only answer questions based on project’s pathogen of interest.

LABORATORY NETWORK ACTIVITIES
Q ID	Question	Answer options	Notes
7.	Does this site participate in a laboratory network or referral network? (Only asked of laboratories or HCFs with lab)	Yes
7.		No
		Don’t know
		Does not apply
8.	Has this site agreed to (or is it required to) submit or forward isolates? (Only asked of laboratories or HCFs with lab)	Yes
		No (end of form)
		Don’t know (end of form)
		Other (Please specify): __________________
9.	Which of the following testing methods are routinely performed at this site/laboratory? Select all that apply.	Culturing
		Antimicrobial Susceptibility Testing (AST and ASFT) (e.g., e test, disk diffusion, broth microdilution)
		Phenotypic Testing (e.g., MALDI-TOF, Vitek2, API, etc.)
		Genotypic Testing/ Polymerase chain reaction (PCR) -
		Sequencing (e.g., WGS, short-read Illumina, long-read ONT, direct amplicon sequencing, NGS, etc.)
		Other (Please specify):_______________
		Unknown
For each test type selected above, please answer the following:
	Testing methods performed on project pathogen of interest (select all that apply)	Culturing – only in context of project pathogen(s) of interest Enteric bacteria culture Invasive bacteria culture N. gonorrhoeae culture Candida sp. Culture Other fungal culture Other bacterial culture Other (please specify): ; Unknown AST – only in context of project pathogen(s) of interest Broth microdilution (e.g. sinsititre); Disk diffusion; Gradient test/E test; Agar dilution; Vitek 2 Other automated device (e.g. Phoenix, Microscan) Other (please specify):; Unknown Phenotypic – only in context of project pathogen(s) of interest API (manual) MALDI-TOF (e.g. Bruker, Vitek MS) Vitek 2 Chromogenic Media (e.g. CHROMagar) Colormetric Tests (e.g. Carba NP, Blue-Carba) Lateral Flow Assay (e.g. Carba 5) mCIM Serotyping Other biochemical tests Other (please specify): ; Unknown Genotypic – only in context of project pathogen(s) of interest PCR RT-PCR/qPCR Cepheid Xpert (e.g. Carba-R) LAMP Hologic Panther Other (specify):; Unknown WGS – only in context of project pathogen(s) of interest What type of sequencing are you doing? Whole Genome Sequencing Short-read Long-read Direct Amplicon Sequencing Next Generation Sequencing Sanger Sequencing Other, please specify What instrument(s) are you using? Illumina Please specify machine: MiSeq NextSeq MiniSeq Other, please specify: Pacific Bio (PacBio) Please specify machine: Revio Vega Onso Other, please specify: Oxford Nanopore Technologies Please specify machine: MinION GridION PromethION Other, please specify: Other, please specify
	ii. Total testing volume (during budget period)	Open ended
	iii. Total number of personnel that received training in testing method	Integer
***e) Sequencing only	iv. Total number of personnel trained to perform bioinformatics⁶ analysis of WGS data	Integer
***e) Sequencing only	v. Describe the bioinformatics pipelines being utilized to analyze data	Open ended
10.	Does this site have a program or any activities that focus on retaining staff⁷ with institutional and technical knowledge once they are trained on any of the testing methods listed previously?	a) Yes ( 10.a.)
		No
		Don’t know
		Does not apply
	10.a.	If yes, please describe:
11.	Describe how laboratory data and results are managed and what platform (e.g., Laboratory Information Management System (LIMS), etc.) is used for data management at this laboratory/facility.	a) Data is managed manually
		b) Laboratory Information Management System (LIMS)
		Sample Management System
		N/A for this reporting period
		Unknown
		Other (please specify):
12.	If applicable, describe data management in the field or at point of collection (e.g., environmental surveillance sites, etc.) as well as in the lab.	Open ended
13.	Is regular external quality assessment performed for AR testing at this project’s participant laboratories?	a) Yes ( 13.a.)
		b) No
		c) Don’t Know
		d) Does not apply
	13.a. Please describe the type and frequency of these EQA activities (e.g., PulseNet EQA, 2 bacterial specimens/ year for identification and AST, etc)	Open ended
	Please use this space to include any additional information about this partner/ laboratory/ healthcare facility	Open ended

SECTION 3: SURVEILLANCE ACTIVITIES

Please answer the following questions based on current surveillance efforts for this organization's Global AR Lab & Response Network project. Do not answer questions based on future efforts.

SURVEILLANCE ACTIVITIES
Q ID	Question	Answer options	Notes
1.	Are epidemiological data elements collected with samples tested under this project?	Yes ( 1.a.)
1.		No ( 1.b.)
		Don’t know
	1.a. If yes, please	Describe what data elements are being collected. (Open ended)
		List each of the sites collecting these elements within the project and indicate if the information is shared with public health for decision making. (Open ended)
	1.b. If no, please	i. List the barriers to collecting epidemiological data elements at sites throughout the referral network? (Open ended)
2.	Are the collected data for this project (e.g., phenotypic, genotypic, and NGS) integrated into subnational, national, or global databases?	Yes (à 2.a.)
		b) No ( 2.b.)
		c) Don’t Know
	2.a. If yes, please	i. Describe what database(s) the data were reported to. Please list all. (Open ended)
		ii. Indicate the frequency of data sharing with national-level decision makers (e.g., MoHs, NPHIs, etc.)? (Open ended)	a) Daily b) Weekly c) Bi-weekly d) Quarterly e) Annually f) Other (please specify):
	2.b.	If no, please list any barriers to data integration. (Open ended)
3.	Have any alerts⁸ or findings from the lab or facility required a local response (e.g., within facility or local area, data sharing, PPS, etc.)?	a) Yes ( 3.a.)
3.		b) No
		c) Don’t Know
	3.a.	If yes, please list the entities involved, response activities, and how data was shared. (Open ended)
4.	Have any alerts or findings from the lab or facility been detected which required a sub-national or national response (e.g., new organism/type of resistance or large outbreak)?	a) Yes ( 4.a.)
		b) No
	4.a.	If yes, please list the entities involved, response activities, and how data was shared. (Open ended)
	Please use this space to include any additional information related to this organization's surveillance activities.	Open ended

-----------------------------------------------END OF FORM 2------------------------------------------------------------------

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1 Implementation: The execution or practice of a plan, a method, or any design, idea, model, specification, standard or policy for doing something. As such, implementation is the action that must follow any preliminary thinking for something to happen.

2 Reviewed: have any SMEs looked over and provided feedback or help on major products developed through this project? This question aims to understand collaborative between CDC SMEs and recipients

3 National or central: quality assurance performed by national or central level government laboratory(s)

4 CDC-supported: any training activities or opportunities related to the implementation of the Global AR Lab and Response Network where CDC provided financial or technical support.

5 This can apply to the partner as a whole or contributions made at the individual lab site level

6 Bioinformatics: the science of collecting and analyzing complex biological data.

7 Refers to any efforts undertaken by the local/national government or other partners to ensure that institutional knowledge remains at the laboratory site

8 Alert: Any newly detected** antimicrobial resistance findings that may influence surveillance and control practices.

** Examples of newly detected antimicrobial resistance include:

Exceptional phenotypes that have not previously been reported or are very rare; and
Novel resistance genotypes that are associated with mechanisms of resistance that have a high public health impact (i.e., high potential for spread and health impact) or pose serious challenges in laboratory detection and surveillance

Source: GLASS Emerging antimicrobial resistance reporting framework (GLASS-EAR)

File Type	application/vnd.openxmlformats-officedocument.wordprocessingml.document
Author	Form Approved
File Modified	0000-00-00
File Created	2025-05-29

GARLRN Performance Measure Tool

[OADPS] The Performance Measures Project: Improving Performance Measurement and Monitoring by CDC Programs

GARLRN PM Tool_Y4Final_Apr2025

[OPPE] The Global Antimicrobial Resistance (AR) Laboratory and Response Network (Global AR Lab and Response Network) [2024-2026] NCEZID GARLRN

OMB: 0920-1282

Contents

INTRODUCTION