Pre Test

Experimental Study on the Public Display of Lists of Harmful and Potential Harmful Tobacco Constituents

HPHC_Prototype1RollYourOwn10

Pre Test

OMB: 0910-0736

Document [pdf]
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U.S. Food and Drug Administration

Logo Sheet 1298.01

Tobacco Product: Brand X Roll Your Own Tobacco
All tobacco products contain chemicals.

KEY

The purpose of this list is to provide information about the chemicals in this tobacco product

Chemicals have been linked to:

that researchers have linked to health problems. Research is on going to find out which chemicals
in tobacco and tobacco smoke cause harm.

Cancer
Lung Disease

There may be other health problems and chemicals that have not been discovered yet.

Heart and Blood Vessel Problems

Tobacco companies test their tobacco for these chemicals and report the amounts to the FDA.
TOBACCO

Please note: There is no safe tobacco product. Based on what we currently know, you can not

Reproductive Problems

tell your chance of developing a health problem by the number of chemicals or the amount of a
chemical in a tobacco product.

Addiction

per gram

ND

SMOKE

TOBACCO

F
Amount
per gram
Per Gram

Acetaldehyde
F
FP L A N TAcetamide

per gram

n

FOUND IN

&

amount per
gram of
tobacco

Acetone

FOUND IN

SMOKE

F

F

Acrolein

F

Acrylamide

n

F

Acrylonitrile

n

PLANT

amount per
gram of
tobacco

&

F

amount per
cigarette

Aflatoxin B1
S4-Aminobiphenyl
MOKE
FOUND IN

amount per
cigarette

n

n

n

Where do these chemicals
come from?
per gram

n

amount per
gram of
tobacco

n
n

F

2-Aminonaphthalene

n

170 - 370 mg

F

Ammonia

F

F

Anabasine

F

F

o-Anisidine

n

40 - 120 ng

F

Arsenic

n

F

A-α-C (2-Amino-9H-pyrido[2,3-b]indole)

n

F

Benz[a]anthracene

n

F

Benz[j]aceanthrylene

n

F

F

Benzene

n

n

F

F

Benzo[b]fluoranthene

n

n

F

Benzo[k]fluoranthene

n

n

F

Benzo[b]furan

n

F

Benzo[a]pyrene

n

F

Benzo[c]phenanthrene

n

F

Beryllium

n

F

1,3-Butadiene

n

n

n

41 - 62ng

F

Cadmium

n

n

n

F

F

Caffeic acid

n

F

Carbon monoxide

F

Catechol

n

F

Chlorinated dioxins/furans

n

F

F

Chromium

n

F

F

Chrysene

n

n

F

F

Cobalt

n

n

F

F

per
cigarette

n

FOUND IN

n
n

n

n
n

n
n
n

n

Coumarin (banned in food)

F
F

F

Cresols (o-, m-, and p-cresol)

n

F

F

Crotonaldehyde

n

F

Cyclopenta[c,d]pyrene

n

F

Dibenz[a,h]anthracene

n

F

Dibenzo[a,e]pyrene

n

F

Dibenzo[a,h]pyrene

n

F

Dibenzo[a,i]pyrene

n

F

Dibenzo[a,l]pyrene

n

F

F

2,6-Dimethylaniline

n

F

F

Ethyl carbamate (urethane)

n

FOUND IN

P L Afrom
NT
Many of these chemicals come
the tobacco leaf and the smoke.
The rest come from the filter, glue, ink,
paper and additives.

1-Aminonaphthalene

F

per
cigarette

SMOKE

n

F

F

SMOKE

TOBACCO

n

F

FOUND IN

n

n

F
per
cigarette

TOBACCO

The information is not currently
available

Amount per
cigarette
Per Cigarette CHEMICAL

SMOKE

Not Detected

n

n

A machine is used to test for these chemicals. The amount of chemical that gets into the body may be
higher or lower depending on how a person uses the tobacco product. Companies may use different tests to
measure these chemicals. Results may vary.

PLANT

amount per
gram of
tobacco

mg= milligram
µg = microgram
ng = nanogram
pg= picogram

&

FOUND IN

SMOKE

amount per
cigarette

&

S

U.S. Food and Drug Administration

Logo Sheet 1298.01

TOBACCO

Tobacco Product: Brand X Roll Your Own Tobacco
per gram

KEY
SMOKE

TOBACCO

Chemicals have been linked to:
Cancer

Amount
per gram
Per Gram

Amount per
cigarette
Per Cigarette
CHEMICAL

F

Lung Disease
n

Ethylbenzene

F

TEthylene oxide
FP L A N
amount per

F

F

gram of
tobacco

&

Formaldehyde

FOUND IN

SMOKE

amount per
cigarette

n

n

n

n

Furan

per
cigarette

F

Glu-P-1 (2-Amino-6-methyldipyrido[1,2-a:3',2'-d ]
imidazole)

n

FOUND IN

F

Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole)

n

PLANT

amount per
gram of
tobacco

&

F

SHydrazine
MOKE
FOUND IN

n

amount per
cigarette

n
n

Hydrogen cyanide

F

Indeno[1,2,3-cd]pyrene

n

F

IQ (2-Amino-3-methylimidazo[4,5-f]quinoline)

n

F

Isoprene

n

F

Lead

n

F

MeA-α-C (2-Amino-3-methyl)-9H-pyrido[2,3-b]indole)

n

F

F

Mercury

n

F

F

Methyl ethyl ketone

F

5-Methylchrysene

n

0.1 – 1.6 µg

F

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

n

F

F

Naphthalene

n

n

F

F

Nickel

n

n

11.3 – 26.7 mg

F

Nicotine

F

Nitrobenzene

n

F

Nitromethane

n

F

2-Nitropropane

n

F

F

N-Nitrosodiethanolamine (NDELA)

n

F

F

N-Nitrosodiethylamine (NDEA)

n

F

F

N-Nitrosodimethylamine (NDMA)

n

F

F

N-Nitrosomethylethylamine

n

N-Nitrosomorpholine (NMOR)

n

F

F

F

Not Detected
TOBACCO

The information is not currently
available
per gram

n

n
SMOKE

TOBACCO

n

Where do these chemicals
come from?
per gram

N-Nitrosonornicotine (NNN)

n

F

F

N-Nitrosopiperidine (NPIP)

n

F

F

N-Nitrosopyrrolidine (NPYR)

n

F

N-Nitrososarcosine (NSAR)

n

F

Nornicotine

per
cigarette

FOUND IN

SMOKE

P L Afrom
NT
Many of these chemicals come
the tobacco leaf and the smoke.
The rest come from the filter, glue, ink,
paper and additives.
amount per
gram of
tobacco

n

F

n

n

per
cigarette

n

FOUND IN

PLANT

amount per
gram of
tobacco

mg= milligram
µg = microgram
ng = nanogram
pg= picogram

n
n

n

n

n

F

Phenol

F

PhIP (2-Amino-1-methyl-6-phenylimidazo [4,5-b]
pyridine)

n

F

F

Polonium-210

n

F

F

Propionaldehyde

F

F

Propylene oxide

n

F

F

Quinoline

n

F

F

Selenium

F

F

Styrene

n

F

F

2-Toluidine

n

F

F

Toluene

F

Trp-P-1 (3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole)

n

F

Trp-P-2 (1-Methyl-3-amino-5H-pyrido[4,3-b]indole )

n

F

Uranium-235

n

n

F

Uranium-238

n

n

F

Vinyl acetate

n

n

F

Vinyl chloride

n

F

ND

n

n

0.9 – 6.9 µg

F

Reproductive Problems
Addiction

F

F

n

n

F

F

Heart and Blood Vessel Problems

FOUND IN

SMOKE

n
n

n

n

A machine is used to test for these chemicals. The amount of chemical that gets into the body may be
higher or lower depending on how a person uses the tobacco product. Companies may use different tests to
measure these chemicals. Results may vary.

&

FOUND IN

SMOKE

amount per
cigarette

&

S


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