Pre Test

Experimental Study on the Public Display of Lists of Harmful and Potential Harmful Tobacco Constituents

HPHC_Prototype4CigaretteNoGraphs05

Pre Test

OMB: 0910-0736

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U.S. Food and Drug Administration

Logo Sheet 1298.01

Tobacco Product: Brand X Cigarette
KEY
Tobacco
Amount
Per Gram

Smoke
Amount
Per Cigarette CHEMICAL

Chemicals have been linked to:
CA

LD

Acetaldehyde

n

n

F

Acetamide

n

F

F

Acetone

n

F

60 – 240 µg

Acrolein

n

770 - 864 µg

F

Acrylamide

n

3 - 15 µg

Acrylonitrile

n

Aflatoxin B1

n

4-Aminobiphenyl

n

3 - 4 ng

1-Aminonaphthalene

n

ND

2-Aminonaphthalene

n

ND

HB

n

n

Ammonia

F

F

Anabasine

F

F

o-Anisidine

n

40 - 120 ng

F

Arsenic

n

F

A-α-C (2-Amino-9H-pyrido[2,3-b]indole)

n

F

Benz[a]anthracene

n

F

Benz[j]aceanthrylene

n

Benzene

n

n

n
n

n

F

Benzo[b]fluoranthene

n

n

F

Benzo[k]fluoranthene

n

n

F

Benzo[b]furan

n

8.5 – 17.6 ng

Benzo[a]pyrene

n

F

Benzo[c]phenanthrene

n

F

Beryllium

n

F

1,3-Butadiene

n

n

n

41 - 62 ng

F

Cadmium

n

n

n

F

F

Caffeic acid

n
n

Carbon monoxide

F

Catechol

n
n

n

F

Chlorinated dioxins/furans

F

F

Chromium

n

F

F

Chrysene

n

n

F

F

Cobalt

n

n

n

F

F

Cresols (o-, m-, and p-cresol)

n

F

ND

Crotonaldehyde

n

F

Cyclopenta[c,d]pyrene

n

F

Dibenz[a,h]anthracene

n

F

Dibenzo[a,e]pyrene

n

F

Dibenzo[a,h]pyrene

n

F

Dibenzo[a,i]pyrene

n

F

Dibenzo[a,l]pyrene

n

F

2,6-Dimethylaniline

n

F

F

Ethyl carbamate (urethane)

n

F

F

Ethylbenzene

n

F

Ethylene oxide

n

n

10.3 -25 µg

Formaldehyde

n

n

F

Furan

n

F

Glu-P-1 (2-Amino-6-methyldipyrido[1,2-a:3',2'-d]
imidazole)

n

F

Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole)

n

F

F

Hydrazine

n

F

F

Hydrogen cyanide

F

Indeno[1,2,3-cd]pyrene

n

F

IQ (2-Amino-3-methylimidazo[4,5-f]quinoline)

n

Isoprene

n

F

Lead

n

F

MeA-α-C (2-Amino-3-methyl)-9H-pyrido[2,3-b]indole)

n

F

Mercury

n

F

F

450 - 1000 µg
F
F

n

Coumarin (banned in food)

F

Lung Disease

HB

Heart and Blood Vessel Problems

RP

Reproductive Problems

AD

Addiction

ND

Not Detected

F

The information is not currently

n

F

F

LD

n

12 - 50 µg

14 - 23 mg

Cancer

available

F

F

CA

n

10 - 130 µg

F

AD
n

170 - 370 mg

F

RP

n

n
n

n
n

n

n

n
n

A machine is used to test for these chemicals. The amount of chemical that gets into the body may be
higher or lower depending on how a person uses the tobacco product. Companies may use different tests to
measure these chemicals. Results may vary.

mg= milligram
µg = microgram
ng = nanogram
pg= picogram

U.S. Food and Drug Administration

Logo Sheet 1298.01

Tobacco Product: Brand X Cigarette
KEY
Tobacco
Amount
Per Gram
F

Smoke
Amount
Per Cigarette CHEMICAL

Chemicals have been linked to:
CA

LD

Methyl ethyl ketone

F

5-Methylchrysene

n

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

n

0.1 – 1.6 µg

110 - 133 ng

F

F

Naphthalene

n

n

F

F

Nickel

n

n

11.3 – 26.7 mg

0.1-3.0 mg

ND

F

Nitrobenzene

n

F

Nitromethane

n

F

2-Nitropropane

n

F

F

N-Nitrosodiethanolamine (NDELA)

n

F

F

N-Nitrosodiethylamine (NDEA)

n

F

F

N-Nitrosodimethylamine (NDMA)

n

F

F

N-Nitrosomethylethylamine

n

N-Nitrosomorpholine (NMOR)

n

n

Nicotine

0.9 – 6.9 µg

154 - 196 ng

N-Nitrosonornicotine (NNN)

n

F

F

N-Nitrosopiperidine (NPIP)

n

F

F

N-Nitrosopyrrolidine (NPYR)

n

F

N-Nitrososarcosine (NSAR)

n

F

Nornicotine

n

n

n

CA

Cancer

LD

Lung Disease

HB

Heart and Blood Vessel Problems

RP

Reproductive Problems

AD

Addiction

ND

Not Detected
The information is not currently
available

n
n

n

n

n

Phenol

F

PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b]
pyridine)

n

F

F

Polonium-210

n

F

F

Propionaldehyde

F

F

Propylene oxide

n

F

F

Quinoline

n

F

F

Selenium

F

F

Styrene

n

F

F

2-Toluidine

n

F

ND

Toluene

F

Trp-P-1 (3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole)

n

F

Trp-P-2 (1-Methyl-3-amino-5H-pyrido[4,3-b]indole )

n

F

Uranium-235

n

n

F

Uranium-238

n

n

F

Vinyl acetate

n

n

F

Vinyl chloride

n

F

AD

F

F

F

RP

n

F

F

HB

n
n

n

n

A machine is used to test for these chemicals. The amount of chemical that gets into the body may be
higher or lower depending on how a person uses the tobacco product. Companies may use different tests to
measure these chemicals. Results may vary.

mg= milligram
µg = microgram
ng = nanogram
pg= picogram


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