Pre Test

Experimental Study on the Public Display of Lists of Harmful and Potential Harmful Tobacco Constituents

HPHC_Prototype5Cigarette3

Pre Test

OMB: 0910-0736

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U.S. Food and Drug Administration

Logo Sheet 1298.01

Tobacco Product: Brand X Cigarette
KEY
Tobacco
Amount
Per Gram
F

Smoke
Amount
Per Cigarette CHEMICAL
770 - 864 µg

Acetaldehyde

60 – 240 µg

Acrolein

Chemicals have been linked to:
CA

LD

n

n
n

Acrylonitrile

n

4-Aminobiphenyl

n

3 - 4 ng

1-Aminonaphthalene

n

ND

2-Aminonaphthalene

n

3 - 15 µg
ND

HB

RP

n
n

n

n

Ammonia

170 - 370 mg

10 - 130 µg

40 - 120 ng

F

Arsenic

n

n

n

F

12 - 50 µg

Benzene

n

n

n

F

8.5 – 17.6 ng

Benzo[a]pyrene

n

F

1,3-Butadiene

n

n

n

F

Cadmium

n

n

n

41 - 62 ng

AD

Carbon monoxide

F

10 - 20 µg

Crotonaldehyde

n

F

10.3 -25 µg

Formaldehyde

n

450 - 1000 µg

Isoprene

n

0.1 – 1.6 µg

110 - 133 ng

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

n

11.3 – 26.7 mg

0.1-3.0 mg

Nicotine

0.9 – 6.9 µg

154 - 196 ng

N-Nitrosonornicotine (NNN)

F

ND

n

n
n

F

Smoke
Amount
Per Cigarette CHEMICAL

CA

F

Acetamide

n

F

Acetone

F

Acrylamide

n

Aflatoxin B1

n

n

LD

HB

F

Anabasine

F

o-Anisidine

n

F

A-α-C (2-Amino-9H-pyrido[2,3-b]indole)

n

F

Benz[a]anthracene

n

F

Benz[j]aceanthrylene

n

F

Benzo[b]fluoranthene

n

n

F

Benzo[k]fluoranthene

n

n

F

Benzo[b]furan

n

F

Benzo[c]phenanthrene

n

F

F

Beryllium

n

F

F

Caffeic acid

n

F

F

Catechol

n

F

Chlorinated dioxins/furans

n

F

Chromium

n

F

F

Chrysene

n

n

F

F

Cobalt

n

n

F

n

n
n

n

Coumarin (banned in food)

F
F

Cresols (o-, m-, and p-cresol)

n

F

Cyclopenta[c,d]pyrene

n

F

Dibenz[a,h]anthracene

n

F

Dibenzo[a,e]pyrene

n

F

Dibenzo[a,h]pyrene

n

F

Dibenzo[a,i]pyrene

n

F

Dibenzo[a,l]pyrene

n

F

F

2,6-Dimethylaniline

n

F

F

Ethyl carbamate (urethane)

n

F

F

Ethylbenzene

n

F

Ethylene oxide

n

F

Furan

n

F

AD

n

F

F

RP

n

F
F

Lung Disease

HB

Heart and Blood Vessel Problems

RP

Reproductive Problems

AD

Addiction

ND

Not Detected
The information is not currently
available

The information is not currently available on the following chemicals.
Tobacco
Amount
Per Gram

LD

n

n

Toluene

Cancer

F

n

14 - 23 mg

CA

n

n
n

n

A machine is used to test for these chemicals. The amount of chemical that gets into the body may be
higher or lower depending on how a person uses the tobacco product. Companies may use different tests to
measure these chemicals. Results may vary.

mg= milligram
µg = microgram
ng = nanogram
pg= picogram

U.S. Food and Drug Administration

Logo Sheet 1298.01

Tobacco Product: Brand X Cigarette
KEY
Tobacco
Amount
Per Gram

Smoke
Amount
Per Cigarette CHEMICAL

Chemicals have been linked to:
CA

F

Glu-P-1 (2-Amino-6-methyldipyrido[1,2-a:3',2'-d]
imidazole)

n

F

Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole)

n

F

F

Hydrazine

n

F

F

Hydrogen cyanide

F

Indeno[1,2,3-cd]pyrene

n

F

IQ (2-Amino-3-methylimidazo[4,5-f]quinoline)

n

F

Lead

n

F

LD

n

MeA-α-C (2-Amino-3-methyl)-9H-pyrido[2,3-b]indole)

n

F

Mercury

n

F

F

Methyl ethyl ketone

F

5-Methylchrysene

n

F

F

Naphthalene

n

n

F

F

Nickel

n

n

F

F

Nitrobenzene

n

n

F

Nitromethane

n

F

2-Nitropropane

n

F

F

N-Nitrosodiethanolamine (NDELA)

n

F

F

N-Nitrosodiethylamine (NDEA)

n

F

F

N-Nitrosodimethylamine (NDMA)

n

F

F

N-Nitrosomethylethylamine

n

N-Nitrosomorpholine (NMOR)

n

CA

Cancer

LD

Lung Disease

HB

Heart and Blood Vessel Problems

RP

Reproductive Problems

AD

Addiction

ND

Not Detected

n
n

n

F

F

N-Nitrosopiperidine (NPIP)

n

F

F

N-Nitrosopyrrolidine (NPYR)

n

F

N-Nitrososarcosine (NSAR)

n

F

Nornicotine

F

The information is not currently
available

n

mg= milligram
µg = microgram
ng = nanogram
pg= picogram

n
n

n

n

n

F

Phenol

F

PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b]
pyridine)

n

F

F

Polonium-210

n

F

F

Propionaldehyde

F

F

Propylene oxide

n

F

F

Quinoline

n

F

F

Selenium

F

F

Styrene

n

F

F

2-Toluidine

n

F

Trp-P-1 (3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole)

n

F

Trp-P-2 (1-Methyl-3-amino-5H-pyrido[4,3-b]indole )

n

F

Uranium-235

n

n

F

Uranium-238

n

n

F

Vinyl acetate

n

n

F

Vinyl chloride

n

F

AD

n

n

F

F

RP

n

F

F

HB

n
n

A machine is used to test for these chemicals. The amount of chemical that gets into the body may be
higher or lower depending on how a person uses the tobacco product. Companies may use different tests to
measure these chemicals. Results may vary.


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