[NCEZID] National Wastewater Surveillance System for Infectious Disease to Inform Public Health Action

Forms and Documents

Forms and supporting documents for this ICR

Document	Type	Status	Availability
16_Attachment15_60_Day_FRN_Summary_Comments.docx	Public Comments	Uploaded 2026-09-28	Available
15_Attachment_14_60_Day_Comments_CDC_2026_0266.csv	Public Comments	Uploaded 2026-09-28	Available
17_Attachment 16 - 1CDP PIA.pdf	Supplementary Document	Uploaded 2026-09-28	Available
14a_Attachment_13_Human_Subjects_Determination_2026.pdf	Supplementary Document	Uploaded 2026-09-28	Available
04_Attachment_02_Published_60_Day_FRN.pdf	Supplementary Document	Uploaded 2026-09-28	Available
03_Attachment_01_Authorizing Legislation_Section 301 of the Public Health Service Act (42 USC 241).pdf	Supplementary Document	Uploaded 2026-09-28	Available
02_Supporting Statement B.docx	Supporting Statement B	Uploaded 2026-09-28	Available
01_Supporting Statement A_NWSS_09_14_2026_final.docx	Supporting Statement A	Uploaded 2026-10-05	Available

IC Document Collections

Information collection document groups

IC ID	Collection	Type	Status	Form
263102	Component 3 - STLT Health Dept Case Data	Other-Template	Removed
263101	Component 2 - STLT and Wastewater Utility Staff	Other-Template	Modified
263100	Component 2 - STLT Health Dept Sewershed	Other-Web Upload Screenshot	Removed
263099	Component 1 - Private Laboratory	Other-Template	Modified
263098	Component 1 - Wastewaters Utilities Staff	Other-Template	Removed
263097	Component 1 - STLT Health Depts	Other-Template	Modified

ICR Details

OMB Control No: 0920-1422	ICR Reference No: 202609-0920-006
Status: Received in OIRA	Previous ICR Reference No: 202310-0920-009
Agency/Subagency: HHS/CDC	Agency Tracking No: 0920-26-0113
Title: [NCEZID] National Wastewater Surveillance System for Infectious Disease to Inform Public Health Action
Type of Information Collection: Revision of a currently approved collection	Common Form ICR:  No
Type of Review Request: Regular	Date Submitted to OIRA: 10/06/2026

table that charts list comparision

	Requested	Previously Approved
Expiration Date	36 Months From Approved	12/31/2026
Responses	195,733	3,947,595
Time Burden (Hours)	453,505	695,941
Cost Burden (Dollars)	0	0

---

Abstract: The National Wastewater Surveillance System collects community-level wastewater samples to detect and track respiratory viruses and other emerging infectious diseases, with the goal of informing timely public health action. Participating health departments, utilities, and laboratories collect and test grab or composite wastewater samples (at least weekly) for pathogen RNA/DNA, submit concentration and sequencing data to CDC platforms (1CDP and AMD), and may upload sewershed spatial files and de-identified clinical crosswalks. Data from wastewater surveillance will be used to track infection trends or disease presence in communities where samples are collected and serve to inform the general public of disease risks, and as an independent data source to alert public health officials and professionals. This Revision includes adjustments to the instruments and the burden.

---

Authorizing Statute(s): US Code: 42 USC 241 Name of Law: PHSA
  

Citations for New Statutory Requirements: None

---

Associated Rulemaking Information
RIN:	Stage of Rulemaking:	Federal Register Citation:	Date:
	Not associated with rulemaking

---

Federal Register Notices & Comments
60-day Notice:	Federal Register Citation:	Citation Date:
	91 FR 8884	02/24/2026
30-day Notice:	Federal Register Citation:	Citation Date:
	91 FR 63284	10/05/2026
Did the Agency receive public comments on this ICR? Yes

---

Number of Information Collection (IC) in this ICR: 3

table that charts list of burden

IC Title	Form No.	Form Name
Component 1 - Private Laboratory
Component 1 - STLT Health Depts
Component 1 - Wastewaters Utilities Staff
Component 2 - STLT Health Dept Sewershed
Component 2 - STLT and Wastewater Utility Staff
Component 3 - STLT Health Dept Case Data

---

ICR Summary of Burden

table that charts list of burden

	Total Request	Previously Approved	Change Due to New Statute	Change Due to Agency Discretion	Change Due to Adjustment in Estimate	Change Due to Potential Violation of the PRA
Annual Number of Responses	195,733	3,947,595	0	-3,636,362	-115,500	0
Annual Time Burden (Hours)	453,505	695,941	0	-89,811	-152,625	0
Annual Cost Burden (Dollars)	0	0	0	0	0	0

Burden increases because of Program Change due to Agency Discretion: Yes

Burden Increase Due to: Miscellaneous Actions

Burden decreases because of Program Change due to Agency Discretion: Yes

Burden Reduction Due to: Miscellaneous Actions

Short Statement: Burden was adjusted based on additional respondents, burden time adjustments, and instrument removal.

---

Annual Cost to Federal Government: $33,166,520

Does this IC contain surveys, censuses, or employ statistical methods? No

Does this ICR request any personally identifiable information (see OMB Circular No. A-130 for an explanation of this term)? Please consult with your agency's privacy program when making this determination.     No

Does this ICR include a form that requires a Privacy Act Statement (see 5 U.S.C. §552a(e)(3))? Please consult with your agency's privacy program when making this determination.     No

Is this ICR related to the Affordable Care Act [Pub. L. 111-148 & 111-152]? No

Is this ICR related to the Dodd-Frank Wall Street Reform and Consumer Protection Act, [Pub. L. 111-203]? No

Is this ICR related to the American Recovery and Reinvestment Act of 2009 (ARRA)? No

Is this ICR related to the Pandemic Response? Yes

---

Common Form ICR:  No

---

On behalf of this Federal agency, I certify that the collection of information encompassed by this request complies with 5 CFR 1320.9 and the related provisions of 5 CFR 1320.8(b)(3).

The following is a summary of the topics, regarding the proposed collection of information, that the certification covers:

(a) It is necessary for the proper performance of agency functions;

(b) It avoids unnecessary duplication;

(c) It reduces burden on small entities;

(d) It uses plain, coherent, and unambiguous language that is understandable to respondents;

(e) Its implementation will be consistent and compatible with current reporting and recordkeeping practices;

(f) It indicates the retention periods for recordkeeping requirements;

(g) It informs respondents of the information called for under 5 CFR 1320.8 (b)(3) about:

(i) Why the information is being collected;

(ii) Use of information;

(iii) Burden estimate;

(iv) Nature of response (voluntary, required for a benefit, or mandatory);

(v) Nature and extent of confidentiality; and

(vi) Need to display currently valid OMB control number;

(h) It was developed by an office that has planned and allocated resources for the efficient and effective management and use of the information to be collected.

(i) It uses effective and efficient statistical survey methodology (if applicable); and

(j) It makes appropriate use of information technology.

If you are unable to certify compliance with any of these provisions, identify the item by leaving the box unchecked and explain the reason in the Supporting Statement.

Certification Date: 10/06/2026

---