Data Methods Guide

Attachment 26_Data Methods Guide.pdf

Evaluation of the Enhancing Diversity of the NIH-funded Workforce Program (NIGMS)

Data Methods Guide

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Attachment 26:
Data Methods
Guide

NIH Diversity Program Consortium (DPC) Methods Guide for Research
Publications Using Consortium-Wide Data
OVERVIEW
This document serves as an introduction to common social science statistical methods used for analyzing
large sample, cross-sectional and longitudinal survey data. It is not meant to be all-inclusive or
methodologically prescriptive; rather, it is intended to provide basic information and resources on
methods that can be used to address questions based on Consortium-Wide Evaluation Plan data and the
DPC Hallmarks of Success. It may also assist in completing the required sections of the DPC Manuscript
Proposal form to request consortium data.
The following section of this document lists potential empirical research questions aimed at examining
Student- and Faculty-level outcomes that correspond to the DPC Hallmarks of Success. These questions
are framed broadly to capture the experiences of students and faculty at BUILD and non-BUILD
institutions. They leave room for developing more specific research questions. For each question, the
corresponding Hallmarks of Success and surveys are identified. These surveys are:
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TFS= HERI‐ The Freshman Survey
CSS = HERI‐ College Senior Survey
FAC = HERI‐ Faculty Survey
FAC‐STEM = HERI‐ Faculty Survey STEM Module
FAC‐MENTOR = HERI‐ Faculty Survey Mentoring Module
D‐SAFS = DPC Student Annual Follow‐up Survey
D‐FAFS = DPC Faculty Annual Follow‐up Survey
NRMN FUP = NRMN Annual Follow-up Survey

Based on the measured outcomes, possible models for analyzing the data are also identified. The final
section of this document provides a description and resources for each statistical method. These methods
include:
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Multiple Linear Regression
Hierarchical Linear Modeling
Binomial Logistic Regression
Ordinal Logistic Regression
Multinomial Logistic Regression
Sequential Logistic Regression
Structural Equation Modeling
Difference in Difference Estimation

The information provided on these methods serves as a general overview; the statistical models used will
depend on the nature of the question and the fit to the data, such as how the explanatory variables and
outcome are measured or constructed (for guidance, see “Choosing the Correct Statistical Test” under the
Other Resources section). A variety of data issues will also need to be considered, including but not
limited to linearity and non-linearity, sample size and power, non-independence or clustering of
observations, and missingness.
POTENTIAL EMPIRICAL RESEARCH QUESTIONS
STUDENTS
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What factors are associated with pursuing a biomedical science degree (versus a non-biomedical
science degree) for BUILD students as compared to non-BUILD students?
o Relevant Hallmarks of Success: STU-7, STU-8, STU-9

Survey Sources of Measures: TFS, CSS, D-SAFS
Possible Method(s) Based on Data: Multinomial Logistic Regression, Ordinal Logistic
Regression, Binomial Logistic Regression, Sequential Logistic Regression
What factors are associated with students’ high levels of participation in research training?
o Relevant Hallmarks of Success: STU-11, STU-14
o Survey Sources of Measures: CSS, D-SAFS
o Possible Method(s) Based on Data: Ordinal Logistic Regression, Binomial Logistic
Regression, Hierarchical Linear Modeling
What factors are associated with students’ high levels of satisfaction with faculty mentorship?
o Relevant Hallmarks of Success: STU-4
o Survey Sources of Measures: CSS, D-SAFS
o Possible Method(s) Based on Data: Ordinal Logistic Regression, Hierarchical Linear
Modeling
How do BUILD students perceive themselves as socially integrating or fitting in on campus, and
how does it affect their academic performance or research engagement?
o Relevant Hallmarks of Success: STU-1, STU-2, STU-3, STU-5, STU-6
o Survey Sources of Measures: TFS, CSS, D-SAFS
o Possible Method(s) Based on Data: Structural Equation Modeling, Ordinal Logistic
Regression
To what extent are interventions associated with BUILD students’ intent to pursue a career in
biomedical research as compared to non-BUILD students?
o Relevant Hallmarks of Success: STU-7, STU-9, STU-10, STU-16, STU-17, STU-18
o Survey Sources of Measures: CSS, D-SAFS
o Possible Method(s) Based on Data: Multinomial Logistic Regression, Binomial Logistic
Regression, Sequential Logistic Regression, Difference in Difference Estimation
What factors are associated with students’ biomedical education and career trajectories?
o Relevant Hallmarks of Success: STU-7, STU-8, STU-9, STU-16, STU-17, STU-18
o Survey Sources of Measures: CSS, D-SAFS
o Possible Method(s) Based on Data: Multinomial Logistic Regression, Binomial Logistic
Regression, Sequential Logistic Regression
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FACULTY
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What factors are associated with BUILD faculty members’ mentoring self-efficacy as compared
to non-BUILD faculty members?
o Relevant Hallmarks of Success: FAC-1, FAC-2, FAC-3, FAC-4, FAC-16
o Survey Sources of Measures: FAC, FAC-STEM, FAC-MENTOR, D-FAFS
o Possible Method(s) Based on Data: Ordinal Logistic Regression, Multiple Linear
Regression, Binomial Logistic Regression, Structural Equation Modeling
What factors are associated with faculty members’ increased mentorship of diverse students and
early career researchers?
o Relevant Hallmarks of Success: FAC-3, FAC-4, FAC-5
o Survey Sources of Measures: FAC, FAC-MENTOR, D-FAFS
o Possible Method(s) Based on Data: Ordinal Logistic Regression, Multiple Linear
Regression, Binomial Logistic Regression, Structural Equation Modeling
What factors or interventions are associated with high-quality faculty mentorship?
o Relevant Hallmarks of Success: FAC-3, FAC-4, FAC-5, FAC-17

Survey Sources of Measures: FAC, FAC-MENTOR, D-FAFS
Possible Method(s) Based on Data: Ordinal Logistic Regression, Multiple Linear
Regression, Binomial Logistic Regression, Structural Equation Modeling, Difference in
Difference Estimation
What factors or interventions are associated with high research productivity for BUILD faculty as
compared to non-BUILD faculty?
o Relevant Hallmarks of Success: FAC-8, FAC-9, FAC-10, FAC-12
o Survey Sources of Measures: FAC, D-FAFS
o Possible Method(s) Based on Data: Binomial Logistic Regression, Ordinal Logistic
Regression, Multiple Linear Regression, Difference in Difference Estimation
To what extent are professional development activities associated with faculty members’
increased research productivity?
o Relevant Hallmarks of Success: FAC-8, FAC-9, FAC-11, FAC-12
o Survey Sources of Measures: FAC, D-FAFS
o Possible Method(s) Based on Data: Binomial Logistic Regression, Ordinal Logistic
Regression, Difference in Difference Estimation
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DESCRIPTIONS AND RESOURCES ABOUT STATISTICAL METHODS
Multiple Linear Regression: can be used to model the relationship between multiple explanatory
variables and an outcome variable, when several assumptions and conditions are met, including: linearity,
homoscedasticity, uncorrelated residuals, absence of multicollinearity, normality of residuals. For
censored dependent variables, a related method is tobit regression.
• Gujarati, Damodar N. 2018. Linear Regression: A Mathematical Introduction. Vol. 177.
Thousand Oaks, CA: Sage Publications. https://us.sagepub.com/en-us/nam/linearregression/book262447
• Lewis-Beck, Colin and Michael Lewis-Beck. 2015. Applied Regression: An Introduction. Vol.
22. Thousand Oaks, CA: Sage Publications. https://us.sagepub.com/en-us/nam/appliedregression/book244616
• Berry, William D. and Stanley Feldman. 1985. Multiple Regression in Practice. No. 50.
Thousand Oaks, CA: Sage Publications. https://us.sagepub.com/en-us/nam/multiple-regressionin-practice/book471
Hierarchical Linear Modeling (HLM)/Multi-Level Modeling (MLM): a form of ordinary least squares
(OLS) regression for analyzing data when the explanatory variables vary at more than one level (e.g.,
hierarchical or nested data), such as students within classrooms within universities. Note: this method
applies to analysis that merges CWEP and Institutional Record data.
• Raudenbush, Stephen W. and Anthony S. Bryk. 2002. Hierarchical Linear Models: Applications
and Data Analysis Methods. 2nd ed. Thousand Oaks, CA: Sage Publications.
• Snijders, Tom A.B. and Roel J. Bosker. 1999. Multilevel Analysis: An Introduction to Basic and
Advanced Multilevel Modeling. Thousand Oaks, CA: Sage Publications.
• Multi-Level Modeling: https://www.mailman.columbia.edu/research/population-healthmethods/multi-level-modeling
Logistic Regression (Binomial, Ordinal, and Multinomial Logistic Regression): for analyzing
outcomes that are measured as binary, ordered (i.e., Likert scale), or categorical variables. Assumptions of
this method include: appropriate outcome structure, independent observations, absence of
multicollinearity, linearity of independent variables and log odds. A related method is probit regression.

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Stoltzfus, Jill C. 2011. “Logistic Regression: A Brief Primer.” Academic Emergency Medicine
18(10): 1099-1104. https://onlinelibrary.wiley.com/doi/full/10.1111/j.1553-2712.2011.01185.x
Long, J. Scott. 1997. Regression Models for Categorical and Limited Dependent Variables.
Thousand Oaks, CA: Sage Publications.
Long, J. Scott and Jeremy Freese. 2006. Regression Models for Categorical and Limited
Dependent Variables Using Stata. College Station, TX: Stata Press.

Sequential Logistic Regression: estimates a series of logistic regression models simultaneously, taking
into account passing through a sequence of transitions. Unlike with multinomial logistic regression,
sequential logistic regression does not assume that the chance of falling into any outcome category is
equal.
• Buis, Maarten L. 2011. “The Consequences of Unobserved Heterogeneity in a Sequential Logit
Model.” Research in Social Stratification and Mobility 29(3): 247-262.
https://www.sciencedirect.com/science/article/pii/S0276562410000703?via%3Dihub
• Buis, Maarten L. 2017. “Not All Transitions Are Equal: The Relationship Between Effects on
Passing Steps in a Sequential Process and Effects on the Final Outcome.” Sociological Methods
& Research 46(3): 649-680. https://journals.sagepub.com/doi/abs/10.1177/0049124115591014
• seqlogit command in STATA: http://maartenbuis.nl/software/seqlogit.html
Structural Equation Modeling: for analysis of unobserved constructs (latent variables) derived from
observed variables (e.g., psychological and psychosocial measures). Structural Equation Modeling is a
confirmatory technique for determining and validating a proposed causal process or model. Related
methods involving latent variables include Factor Analysis and Path Analysis.
• Maruyama, Geoffrey. 1997. Basics of Structural Equation Modeling. Thousand Oaks, CA: Sage
Publications.
• Bollen, Kenneth A. 1989. Structural Equations with Latent Variables. New York, NY: John
Wiley.
• Loehlin, John C. 1998. Latent Variable Models: An Introduction to Factor, Path, and Structural
Analysis. 3rd ed. Mahwah, N.J.: Lawrence Erlbaum Associates.
• Duncan, Otis Dudley. 1966. “Path Analysis: Sociological Examples.” American Journal of
Sociology 72(1): 1-16. https://www.journals.uchicago.edu/doi/abs/10.1086/224256
• Alwin, Duane F., and Robert M. Hauser. 1975. “The Decomposition of Effects in Path Analysis.”
American Sociological Review 40(1): 37-47.
https://www.jstor.org/stable/2094445?seq=1#metadata_info_tab_contents
• Exploratory Factor Analysis: https://www.mailman.columbia.edu/research/population-healthmethods/exploratory-factor-analysis
• Path Analysis: https://www.mailman.columbia.edu/research/population-health-methods/pathanalysis
Difference in Difference Estimation: used to estimate the effect of an intervention when panel or
repeated cross-sectional data are available for both treatment and control groups.
• Difference in Difference Estimation: https://www.mailman.columbia.edu/research/populationhealth-methods/difference-difference-estimation
• Wing, Coady, Kosali Simon, and Ricardo A. Bello-Gomez. 2018. “Designing Difference in
Difference Studies: Best Practices for Public Health Policy Research.” Annual Review of Public
Health 39(1): 453-469. https://www.annualreviews.org/doi/full/10.1146/annurev-publhealth040617-013507

Other Resources
• Choosing the Correct Statistical Test: https://stats.idre.ucla.edu/other/mult-pkg/whatstat/
• General Modeling Techniques: https://www.mailman.columbia.edu/research/population-healthmethods/techniques
• Propensity Score Methods: addresses bias in observational studies; enables comparisons between
treatment and non-treatment groups.
o Propensity Score: https://www.mailman.columbia.edu/research/population-healthmethods/propensity-score
o Austin, Peter C. 2011. “An Introduction to Propensity Score Methods for Reducing the
Effects of Confounding in Observational Studies.” Multivariate Behavioral Research
46(3): 399-424. https://www.tandfonline.com/doi/full/10.1080/00273171.2011.568786
o Austin, Peter C. 2010. “Statistical Criteria for Selecting the Optimal Number of
Untreated Subjects Matched to Each Treated Subject When Using Many-to-One
Matching on the Propensity Score.” American Journal of Epidemiology 172(9): 10921097. https://academic.oup.com/aje/article/172/9/1092/147493
• Agresti, Alan. 1990. Categorical Data Analysis. New York, NY: John Wiley and Sons.
• Powers, Daniel and Yu Xie. 1999. Statistical Methods for Categorical Data Analysis. San Diego,
CA: Academic Press.


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